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Cubs vs Brewers Prediction 9/8/26 MLB Picks Today

Chicago Cubs (81-64) vs. Milwaukee Brewers (89-56)
September 8, 2026 7:40 pm EDT
The Line: Milwaukee Brewers -219 / Chicago Cubs 179; Over/Under: 7.5
(Get latest betting odds)

In this article, we will formulate a Cubs vs Brewers Prediction for this MLB matchup on Tuesday, September 8th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Milwaukee Brewers Preview

The Milwaukee Brewers have an 89-56 record this season and are sitting in the 1st place of the NL Central. They have a 48-25 home record and are coming off a 4-3 home win against the Cubs. They will face the Reds and the Pirates next.

The Milwaukee Brewers have a .256 batting average this season, .339 OBP and .399 Slugging percentage. Milwaukee’s pitching staff has a 3.54 ERA and 1.19 WHIP. Jackson Chourio is the team’s best hitter with a .281 batting average. Brice Turang leads the team in RBI with 85, while Jake Bauers adds a team-high 24 home runs.

Jacob Misiorowski (R) is the projected starting pitcher for the Brewers, and he has a 14-5 record, 1.97 ERA and 0.79 WHIP.

Chicago Cubs Preview

The Chicago Cubs have an 81-64 record this season and are sitting in the 2nd place of the NL Central. They have a 40-33 away record and are coming off a 3-4 away loss against the Brewers. They will face the Pirates and the Braves next.

The Chicago Cubs have a .251 batting average this season, .339 OBP and .431 Slugging percentage. Chicago’s pitching staff has a 4.21 ERA and 1.26 WHIP. Pete Crow-Armstrong is the team’s best hitter with a .281 batting average, while leading the team in RBI with 97, adding a team-high 41 home runs.

David Peterson (L) is the projected starting pitcher for the Cubs, and he has a 7-8 record, 5.39 ERA and 1.56 WHIP.

The Chicago Cubs @ Milwaukee Brewers Betting Trends: September 8, 2026

 

  • Probable Starting Pitcher: Jacob Misiorowski      Record this season: 14-5      ERA: 1.97
  • Home Record: 7-1
  • Last 5 against Cubs: 4-0

Why the Milwaukee Brewers will win

  • The Brewers have won each of their last eight Tuesday games against NL Central opponents.
  • The Cubs have lost four of their last five road games following a loss.
  • The Brewers have covered the run line in each of their last seven Tuesday night games against NL Central opponents.
  • The Cubs have failed to cover the run line in seven of their last eight Tuesday night games against NL Central opponents that held a winning record.
  • The Brewers have won the first inning in five of their last six night games at American Family Field.
  • The Cubs have trailed after 3 innings in three of their last four games as road underdogs.
  • The Brewers have led after 5 innings in 15 of their last 16 Tuesday games as home favorites.

 

  • Probable Starting Pitcher: David Peterson      Record this season: 7-8      ERA: 5.39
  • Road Record: 5-3
  • Last 5 against Brewers: 3-1

Why the Chicago Cubs will win

  • The Cubs have won four of their last five games as road underdogs against NL Central opponents following a loss.
  • The Brewers have lost three of their last four games as favorites following a win.
  • The Cubs have covered the run line in each of their last 13 games as road underdogs.
  • The Brewers have failed to cover the run line in four of their last five games.
  • The Cubs have led after 3 innings in five of their last six night games.
  • The Cubs have led after 5 innings in six of their last seven night games against opponents that held a winning record.

Total Runs Facts

  • Nine of the Brewers’ last 10 home games against NL Central opponents have gone UNDER the total runs line.
  • Eight of the Cubs’ last 10 games against NL Central opponents have gone OVER the total runs line.
  • There has been no run scored during the first inning in each of the Cubs’ last nine road games against NL opponents.
  • There has been at least one run scored in the first inning in each of the Brewers’ last six night games at American Family Field.

Milwaukee Brewers Player Prop Facts

  • Jacob Misiorowski has recorded a win in each of his last four home appearances against opponents that held a winning record.
  • Jacob Misiorowski has recorded eight or more strikeouts in each of his last four home appearances against NL Central opponents.
  • Andrew Vaughn has recorded at least one hit in each of the Brewers’ last 10 games against opponents that held a winning record.
  • Gary Sanchez has hit a home run in three of his last five appearances with his team as a home favorite against the Cubs.
  • Jacob Misiorowski ranks 1st amongst qualified players for Earned Run Average (1.97) this season.

Chicago Cubs Player Prop Facts

  • Pete Crow-Armstrong has hit a home run in each of the Cubs’ last two games.
  • David Peterson has recorded a win in each of his last three road appearances against NL opponents.
  • Alex Bregman has recorded at least one hit in each of the Cubs’ last nine games as underdogs.
  • Pete Crow-Armstrong ranks 2nd in the league in Home Runs (41) this season.

Matchup/League Facts

  • The Brewers rank 1st in the league for hits this season (1259).
  • The Brewers rank 30th in the league for home runs this season (133).
  • The Cubs rank 1st in the league for runs scored this season (771).
  • The Cubs rank 1st in the league for home runs this season (203).

Cubs vs Brewers Prediction

The Brewers are 3-1 in their last 4 meetings against the Cubs but have lost two of their last three meetings in Milwaukee.

In this Cubs vs Brewers Prediction, the Brewers are coming as -210 home favorites. I like the Brewers in this one with Jacob Misiorowski on the mound, who is looking to bounce back off his worst start of the season against the same team a week ago. He has a 7-1 record and 1.62 ERA at home, while David Peterson has a 5.39 ERA and 1.56 WHIP this season and has given up 6 runs against the Brewers in the same matchup on September 2nd. The Brewers also have a better bullpen to relief the Mizz, so I expect them to win this one comfortably and cover the runline.

Nikos Lagouretos's Free Pick: Milwaukee Brewers -1.5

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