Cubs vs Brewers Prediction 8/20/25 MLB Picks Today

In this article we will formulate a Cubs vs Brewers prediction for this MLB game on Wednesday, August 20th at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Chicago Cubs Betting Preview

The Chicago Cubs are 72-54 this year after they won two of the first three games in this series by scores of 0-7, 6-4, and 4-1. In their game three win, Chicago trailed 1-0 early in the game, but they scored the final four runs to get the victory. The Cubs recorded nine hits in the game and they were led by Busch, who went 1-4 with two RBIs in the win. Chicago started Taillon, who allowed five hits and one earned run over 6.0 innings for the win, while Kittredge picked up the save. 

Prior to this series, the Cubs won two out of three against the Pirates, but did lose two out of three against the Blue Jays before that. Chicago has won four of their last five games and they are currently second in the NL Central standings. The Chicago pitching staff has a 3.81 ERA with a 1.21 WHIP and a .243 opponent batting average, while their offense has scored 624 runs with a .250 batting average and a .319 on base percentage this season. Seiya Suzuki has led Chicago with 27 home runs and 86 RBIs, while Pete Crow-Armstrong has added 27 home runs and 79 RBIs this year. The projected starting pitcher for Chicago is Colin Rea, who is 9-5 with a 3.99 ERA and a 1.28 WHIP over 121.2 innings pitched this year. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 79-47 this season after they lost both ends of the doubleheader on Tuesday. In their game three loss, Milwaukee jumped out to a lead in the first inning, but failed to score over the last eight innings for the loss. The Brewers recorded seven hits in the game and they were led by Vaughn, who went 1-4 with one RBI in the loss. Milwaukee started Woodruff, who allowed five hits and three earned runs over 4.1 innings for the loss, while Ashby finished the last 3.2 innings in relief. 

Prior to this series, the Brewers won two out of three against the Reds and all three against the Pirates. Milwaukee has won 15 of their last 18 games and they are currently first in the NL Central standings. The Milwaukee pitching staff has a 3.58 ERA with a 1.23 WHIP and a .230 opponent batting average, while the offense has scored 650 runs with a .258 batting average and a .332 on base percentage this season. Christian Yelich has led Milwaukee with 26 home runs and 87 RBIs, while William Contreras has added 13 home runs and 61 RBIs this year. The projected starting pitcher for Milwaukee is Jacob Misiorowski, who is 4-1 with a 3.89 ERA and a 1.13 WHIP over 34.2 innings pitched this year. 

Why the Cubs will beat the Brewers

• The Cubs have won each of their last eight Wednesday games as underdogs against NL Central opponents.
• The Brewers have lost four of their last five games as favorites against the Cubs following a road loss.
• The Cubs have covered the run line in each of their last 11 Wednesday games as underdogs against NL Central opponents.
• The Brewers have failed to cover the run line in four of their last five games as road favorites against NL Central opponents.
• The Cubs have led after 5 innings in seven of their last eight night games at Wrigley Field against National League opponents.
• The Cubs have led after 3 innings in six of their last seven home night games.

Total Runs Facts

• Five of the Cubs’ last six night games after playing the previous day have gone UNDER the total runs line.
• Eight of the Brewers’ last 10 games as favorites against NL Central opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Brewers’ last seven games as road favorites against NL Central opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Cubs’ last seven games as home underdogs against NL Central opponents.

Chicago Cubs Player Prop Facts

• Kyle Tucker has hit a home run in three of his last five appearances with the Cubs as home underdogs.
• Ian Happ has recorded at least one hit in each of his last nine appearances against the Brewers after playing the previous day.

Milwaukee Brewers Player Prop Facts

• Andrew Vaughn has hit a home run in three of the Brewers’ last five night games against NL Central opponents that held a winning record.
• Jackson Chourio has recorded at least one hit in each of his last 11 road appearances.
• Danny Jansen has recorded a Double in each of his last four appearances with his team as a road favorite against NL Central opponents.

Cubs vs Brewers Prediction 

Chicago was able to get a much needed sweep in the doubleheader on Tuesday, as they have a lot of ground to make up in the race for the Central. The Cubs are 40-24 at home this year, while the Brewers are 37-27 on the road. Milwaukee was the hottest team in the MLB, but they have dropped three of their last four. The Brewers are starting Misiorowski, who has been very good this year, but has allowed seven earned runs and seven hits over his last 5.1 innings. The Cubs are going with Rea, who has allowed two earned runs or fewer in three straight games. I am going to ride with the Cubs once again, as I like the momentum they have created for themselves.