Cubs vs Giants Prediction 5/6/25 MLB Picks Today

In this article, we will formulate a Cubs vs Giants prediction for this MLB game on Tuesday, May 6th at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Chicago Cubs Betting Preview

The Chicago Cubs are 22-14 this season after they won game one in this series by a score of 9-2 on Monday night. Chicago was tied at two in the fourth inning, but they scored the last seven runs in the game for the win. The Cubs recorded nine hits in the game, and they were led by Happ, who went 1-3 with one home run and three RBIs in the win. Chicago started Boyd, who allowed five hits and two earned runs over 6.0 innings in the win, while Thielbar and Hollowell finished the last three innings. 

Prior to this series, the Cubs won two out of three against the Brewers and two out of three against the Pirates. Chicago has won four of their last five games, and they are currently first in the NL Central standings. The Chicago pitching staff has a 3.77 ERA with a 1.28 WHIP and a .240 opponent batting average, while their offense has scored 217 runs with a .262 batting average and a .338 on-base percentage this season. Kyle Tucker has led Chicago with nine home runs, 30 RBIs, and nine stolen bases, while Seiya Suzuki has added nine home runs and 31 RBIs this year. The projected starting pitcher for Chicago is Colin Rea, who is 2-0 with a 1.46 ERA and a 1.05 WHIP over 24.2 innings pitched this season. 

San Francisco Giants Betting Preview

The San Francisco Giants are 22-14 this year after they dropped game one on Monday night. San Francisco tied the game at two in the fourth, but their pitching fell apart in the sixth inning for the loss. The Giants recorded seven hits and they committed four errors in the game, while they were led by Matos, who went 1-4 with one home run and two RBIs in the loss. SF started Roupp, who allowed five hits and two earned runs over 5.0 innings, while Birdsong allowed one earned run and two hits over 0.1 innings of relief. 

Prior to this series, the Giants won three out of four against the Rockies, but did lose both games against the Padres before that. San Francisco has won three of their last four games, and they are currently third in the NL West standings. The San Francisco pitching staff has a 3.44 ERA with a 1.23 WHIP, and a .233 opponent batting average, while the offense has scored 166 runs with a .231 batting average and a .308 on-base percentage this season. Wilmer Flores has led San Francisco with seven home runs and 31 RBIs, while Matt Chapman has added seven home runs and 21 RBIs this year. The projected starting pitcher for San Francisco is Justin Verlander, who is 0-2 with a 4.38 ERA and a 1.30 WHIP over 37.0 innings pitched this year. 

Chicago Cubs Player Prop Facts

• Ian Happ has hit a home run in three of the Cubs’ last four home games against the Giants.
• Ian Happ has recorded at least one RBI in each of the Cubs’ last six games as favorites against the Giants.
• Dansby Swanson has scored at least one run in eight of the Cubs’ last nine night games.
• Nico Hoerner has recorded at least one Single in each of the Cubs’ last nine Tuesday games against opponents that held a winning record.
• Justin Turner has recorded at least one hit in each of his last 11 appearances with his team as a favorite against the Giants.

San Francisco Giants Player Prop Facts

• Wilmer Flores has recorded at least one RBI in four of his last five appearances in night games against NL Central teams that held a winning record.
• Casey Schmitt has recorded a Double in three of his last four appearances against NL Central opponents that held a winning record.
• LaMonte Wade Jr has hit a home run in each of his three previous appearances with the Giants as underdogs against the Cubs.
• Jung Hoo Lee has recorded at least one hit in each of his last 11 appearances with the Giants as underdogs against NL opponents.
• Jung Hoo Lee has recorded at least one Single in each of his last 11 appearances with the Giants as underdogs against NL opponents.
• Heliot Ramos has scored at least one run in nine of the Giants’ last 10 road games against NL opponents.

Cubs vs Giants Prediction 

Chicago was able to erupt in the sixth inning on Monday night to seal the win, and they are now 10-7 at home this year. The Cubs continue to be the highest-scoring team in the MLB, and they have scored at least six runs in four of their last five games. The Giants are 10-9 on the road this season, and they are starting Verlander, who has allowed two earned runs or fewer in three straight starts. Chicago is turning to Rea, who has allowed two earned runs or fewer in five straight outings. Both pitchers have been very strong in recent starts, but I am not a believer in Rea. Take the Giants here.