Cubs vs Marlins Prediction 9/5/26 MLB Picks Today

In this article, we will formulate a Cubs vs Marlins Prediction for this MLB matchup on Saturday, September 5^th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Miami Marlins Preview

The Miami Marlins have a 71-71 record this season and are sitting in 3rd place in the NL East. They have a 42-28 home record and are coming off a 1-6 home loss against the Cubs. They will face the Mets and the Dodgers next.

The Miami Marlins have a .247 batting average this season, .325 OBP, and .398 slugging percentage. Miami’s pitching staff has a 3.97 ERA and 1.26 WHIP. Otto Lopez is the Marlins’ best hitter with a .300 batting average, while leading the team in RBI with 62, adding a team-high 23 home runs.

Ryan Gusto (R) is the projected starting pitcher for the Marlins, with a 1-3 record, 3.86 ERA, and 1.33 WHIP.

Chicago Cubs Preview

The Chicago Cubs have an 80-62 record this season and are sitting in 2nd place in the NL Central. They have a 39-31 road record and are coming off a 6-1 road win against the Marlins. They will face the Brewers and the Pirates next.

The Chicago Cubs have a .251 batting average this season, .339 OBP, and .431 slugging percentage. Chicago’s pitching staff has a 4.16 ERA and 1.26 WHIP. Pete Crow-Armstrong is the Cubs’ best hitter with a .280 batting average, while leading the team in RBI with 91, adding a team-high 38 home runs.

Javier Assad (R) is the projected starting pitcher for the Cubs, with a 6-1 record, 3.46 ERA, and 1.10 WHIP.

The Chicago Cubs @ Miami Marlins Betting Trends: September 5, 2026

• Probable Starting Pitcher: Ryan Gusto      Record this season: 1-3      ERA: 3.86
• Home Record: 1-1
• Last 5 against Cubs: 0-0

Why the Miami Marlins will win

• The underdogs have won seven of the Marlins’ last nine games.
• The Cubs have lost three of their last four games as favorites following a win.
• The Marlins have covered the run line in each of their last seven games as underdogs against NL Central opponents following a home loss.
• The Cubs have failed to cover the run line in five of their last six games against the Marlins following a win.
• The Marlins have won the first inning in three of their last four day games at LoanDepot Park.
• The Marlins have led after 5 innings in five of their last six day games against NL Central opponents that held a winning record.
• The Marlins have led after 3 innings in seven of their last eight day games against NL Central opponents that held a winning record.

• Probable Starting Pitcher: Javier Assad      Record this season: 6-1      ERA: 3.46
• Road Record: 4-1
• Last 5 against Marlins: 0-1

Why the Chicago Cubs will win

• The Marlins have lost each of their last seven games against NL opponents that held a winning record.
• The Cubs have won 14 of their last 15 games against NL East opponents following a win.
• The Marlins have failed to cover the run line in eight of their last nine home games against NL opponents following a loss.
• The favorites have covered the run line in five of the Marlins’ last six games at LoanDepot Park.
• The Marlins have trailed after 5 innings in seven of their last eight games against NL opponents that held a winning record.
• The Cubs have led after 3 innings in seven of their last eight games.

Total Runs Facts

• Four of the Cubs’ last five games as favorites have gone OVER the total runs line.
• Each of the Marlins’ last three games as underdogs against NL opponents have gone UNDER the total runs line.
• There has been no run scored during the first inning in each of the Marlins’ last 11 games against NL Central opponents.
• There has been no run scored during the first inning in each of the Cubs’ last six road games against NL opponents.

Miami Marlins Player Prop Facts

• Griffin Conine has hit a home run in three of the Marlins’ last four day games against opponents that held a winning record.
• Ryan Gusto has recorded four or more strikeouts in three of his last four appearances against NL opponents.
• Javier Sanoja has recorded at least one hit in each of the Marlins’ last eight games against NL opponents that held a winning record.
• Otto Lopez ranks 2nd in the league in Hits (166) this season.

Chicago Cubs Player Prop Facts

• Pete Crow-Armstrong has hit at least one home run in eight of the Cubs’ last 18 games.
• Alex Bregman has recorded at least one hit in each of the Cubs’ last eight games.
• Pete Crow-Armstrong ranks 2nd in the league in Home Runs (39) this season.

Matchup/League Facts

• The Marlins rank T2nd in the league for triples this season (30).
• The Marlins rank 2nd in the league for steals this season (146).
• The Cubs rank 1st in the league for runs scored this season (759).
• The Cubs rank 1st in the league for home runs this season (199).

Cubs vs Marlins Prediction

The Cubs are 7-3 in their last 10 meetings against the Marlins and are 5-2 in their last 7 visits in Miami.

In this Cubs vs Marlins Prediction, the Cubs are coming as -130 road favorites. I like the Marlins in a bounce-back spot today with the red-hot Ryan Gusto on the mound, who has been in excellent form, having given up two runs or less in 10 of his last 11 starts and has better numbers at home. On the flip side, Javier Assad has been weaker on the road with a 4.66 ERA and the Marlins have a better bullpen in their last 10 games, have been very strong at home and fighting for a wild card spot in the NL. Take the Marlins in this one for plus money.