Cubs vs Phillies Prediction 4/22/26 MLB Picks Today

The Philadelphia Phillies and Chicago Cubs meet Wednesday in MLB action at Wrigley Field. Here’s a Cubs vs. Phillies Prediction. This article will include a Cubs vs. Phillies Pick.

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 8-15 on the year and play the Braves and Giants next. The Philadelphia Phillies are batting .227 on the season and have a .312 OBP, and a .369 slugging percentage. The Philadelphia Phillies pitching staff has a 4.18 ERA and a 1.28 WHIP. Bryce Harper leads the Philadelphia Phillies with 23 hits and 13 RBI, while Trea Turner and Brandon Marsh have combined for 43 hits and 18 RBI.

Kyle Backhus gets the ball for the Philadelphia Phillies, and he is 0-0 with a 5.40 ERA and 9 strikeouts this season. Backhus is 0-0 with a 3.86 ERA and 4 strikeouts in his career against the Chicago Cubs.

Chicago Cubs Betting Preview

The Chicago Cubs are 14-9 on the year and play the Dodgers and Padres next. The Chicago Cubs are batting .255 on the season and have a .350 OBP, and a .404 slugging percentage. The Chicago Cubs pitching staff has a 3.45 ERA and a 1.15 WHIP. Nico Hoerner leads the Chicago Cubs with 30 hits and 22 RBI, while Alex Bregman and Ian Happ have combined for 43 hits and 20 RBI.

Matthew Boyd gets the ball for the Chicago Cubs, and he is 1-1 with a 6.75 ERA and 17 strikeouts this season. Boyd is 0-0 with a 2.25 ERA and 8 strikeouts in his career against the Philadelphia Phillies.

Why the Chicago Cubs will win

• The Cubs have won each of their last eight home games against National League opponents that held a losing record.
• The Phillies have lost each of their last seven games.
• The Phillies have failed to cover the run line each of their last 11 games against teams that held a winning record.
• The Cubs have covered the run line in seven of their last eight home games against National League opponents that held a losing record.
• The Cubs have led after 3 innings in each of their last five Wednesday games as home favorites.
• The Phillies have trailed after 5 innings in each of their last six games.

Why the Philadelphia Phillies will win

• The Phillies have won three of their last four games as underdogs following a road loss.
• The Cubs have lost three of their last four Wednesday night games as favorites against NL East opponents.
• The Phillies have covered the run line in 10 of their last 12 games as underdogs following a road loss.
• The Cubs have failed to cover the run line in 15 of their last 20 home games against NL East opponents following a home win.

Total Runs Facts

• Seven of the Cubs’ last eight night games against NL East opponents have gone OVER the total runs line.
• Four of the Phillies’ last five games have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Phillies’ last eight games at Wrigley Field.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last five games between the Phillies and Cubs at Wrigley Field.

Chicago Cubs Player Prop Facts

• Matthew Boyd has recorded six or more strikeouts in each of his last six Wednesday night appearances against teams that held a losing record.
• Matthew Boyd has recorded a win in six of his last eight home appearances against opponents that held a losing record.
• Ian Happ has recorded at least one hit in each of the Cubs’ last 12 home games against NL East opponents.
• Dansby Swanson has hit a home run in three of the Cubs’ last four night games against opponents that held a losing record.

Philadelphia Phillies Player Prop Facts

• Kyle Schwarber has hit a home run in two of the Phillies’ last three games.
• Bryson Stott has recorded a hit in each of his last seven appearances.
• Kyle Schwarber ranks T4th in the league in Home Runs (8) this season.

Matchup/League Facts

• The Cubs rank 3rd in the league for on-base percentage this season (.350).
• The Cubs rank 3rd in the league for walks allowed this season (69).
• The Phillies rank 30th in the league for opponent batting average this season (.278).
• The Phillies rank 29th in the league for hits allowed this season (226).

Cubs vs Phillies Prediction

The Phillies are having a rough week and are hard to get behind in their current form but they’re also still a talented team due for a victory. I’m looking at the over here. Both lineups are talented and both pitchers have small sample sizes. Backhus has just 6.2 innings under his belt, while Boyd has pitched just 9.1 innings. Both guys are still trying to find their footing and have been hit hard in limited sample sizes. These lineups aren’t what you want to see when trying to find a rhythm. I expect offense. Give me the over.