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Diamondbacks vs Padres Pick – MLB Predictions & Odds 4/21/23

San Diego Padres (10-11) vs. Arizona Diamondbacks (11-9)
April 21, 2023 9:40 pm EDT
The Line: Arizona Diamondbacks -105 / San Diego Padres -116; Over/Under: +9
(Get latest betting odds)

The San Diego Padres and Arizona Diamondbacks meet Friday in MLB action at Chase Field. Let’s preview this game and give out a pick and prediction.

The San Diego Padres have scored 9 runs in their last 3 games and 3 or fewer runs in 7 of their last 9 games. The Padres are 2-9 this season when scoring 3 or fewer runs. Xander Bogaerts leads the Padres with 28 hits and 12 RBI, while Manny Machado and Trent Grisham have combined for 36 hits and 16 RBI. Seth Lugo gets the ball, and he is 2-0 with a 2.70 ERA and 17 strikeouts this season. Lugo is 0-1 with a 4.34 ERA and 23 strikeouts in his career against the Diamondbacks.

The Arizona Diamondbacks have scored 18 runs in their last 3 games and 4 or more runs in 5 straight games. The Diamondbacks are 8-3 this season when scoring 4 or more runs. Josh Rojas leads the Diamondbacks with 21 hits and 9 RBI, while Lourdes Gurriel Jr. and Ketel Marte have combined for 37 hits and 13 RBI. Zac Gallen gets the ball, and he is 2-1 with a 3.33 ERA and 28 strikeouts this season. Gallen is 1-3 with a 4.22 ERA and 46 strikeouts in his career against the Padres.

The Padres are 20-9 in their last 29 Friday games and 2-6 in their last 8 overall. The Diamondbacks are 5-2 in their last 7 home games and 18-38 in their last 56 Friday games. The under is 7-3 in Padres last 10 overall. The over is 4-0 in Diamondbacks last 4 overall. The Padres are 19-7 in the last 26 meetings.

This should be a hell of a pitching battle as Seth Lugo and Zac Gallen have been dealing so far this season and they both have good stuff to miss bats. With that said, the Padres’ offense is going to come along sooner than later, we saw flashes of that last night and the return of Fernando Tatís Jr. should help the confidence of the club overall. Give me the Padres and the cheap price.

Randy Chambers's Free Pick: San Diego Padres -116

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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