Dodgers vs Guardians Prediction 4/1/26 MLB Picks Today

The Cleveland Guardians and Los Angeles Dodgers meet Wednesday in MLB action at Dodger Stadium. Here’s a Dodgers vs. Guardians Prediction. This article will include a Dodgers vs. Guardians Pick.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 3-3 on the year and play the Cubs and Royals next. The Cleveland Guardians are batting .188 on the season, have a .269 OBP, and have a .305 slugging percentage. The Cleveland Guardians pitching staff has a 4.50 ERA and a 1.35 WHIP. Steven Kwan leads the Cleveland Guardians with 7 hits and 2 RBI, while Chase DeLauter and Rhys Hoskins have combined for 10 hits and 6 RBI.

Gavin Williams gets the ball for the Cleveland Guardians, and he is 0-1 with a 5.40 ERA and 7 strikeouts this season. Williams is 0-3 with a 13.03 ERA and 8 strikeouts in his career against the Los Angeles Dodgers.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers are 4-1 on the year and play the Nationals and Blue Jays next. The Los Angeles Dodgers are batting .248 on the season and have a .318 OBP, and a .395 slugging percentage. The Los Angeles Dodgers pitching staff has a 2.60 ERA and a 0.96 WHIP. Andy Pages leads the Los Angeles Dodgers with 6 hits and 5 RBI while Miguel Rojas and Max Muncy have combined for 8 hits and 1 RBI.

Yoshinobu Yamamoto gets the ball for the Los Angeles Dodgers, and he is 1-0 with a 3.00 ERA and 6 strikeouts this season. This will be Yamamoto’s second career game against the Cleveland Guardians.

Why the Los Angeles Dodgers will win

• The Dodgers have won each of their last 15 night games after playing the previous day.
• The Guardians have lost six of their last eight games against National League opponents.
• The Guardians have failed to cover the run line in four of their last five night games against teams that held a winning record.
• The Dodgers have covered the run line in three of their last four home games against the Guardians.
• The Dodgers have led after 5 innings in six of their last seven games against the Guardians.

Why the Cleveland Guardians will win

• The Guardians have won each of their last six games as underdogs following a loss.
• The Dodgers have lost each of their last four games as favorites against American League opponents following a home win.
• The Guardians have covered the run line in each of their last 15 Wednesday games as underdogs.
• The Dodgers have failed to cover the run line in seven of their last eight games following a win.
• The Guardians have led after 5 innings in eight of their last nine Wednesday night games against opponents that hold a winning record.
• The Guardians have led after 3 innings in each of their last eight Wednesday road games.

Total Runs Facts

• Nine of the Guardians’ last 10 road games against NL West opponents have gone UNDER the total runs line.
• Five of the Dodgers’ last six games against AL Central opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Dodgers’ last nine Wednesday games against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last six night games against National League opponents.

Los Angeles Dodgers Player Prop Facts

• Shohei Ohtani has hit a home run in three of the Dodgers’ last five games against AL Central opponents.
• Kyle Tucker has recorded at least one hit in 16 of his last 17 appearances at UNIQLO Field at Dodger Stadium.

Cleveland Guardians Player Prop Facts

• Rhys Hoskins has hit a home run in three of his last six road appearances against the Dodgers after playing the previous day.
• Steven Kwan has recorded at least one hit in each of the Guardians’ last 12 Wednesday games.
• Jose Ramirez ranks T5th in the league in Steals (2) this season.

Matchup/League Facts

• The Dodgers rank 2nd in the league for strikeouts against this season (32).
• The Dodgers rank 2nd in the league for opponent batting average this season (.189).
• The Guardians rank T2nd in the league for doubles this season (11).
• The Guardians rank 28th in the league for batting average this season (.188).

Dodgers vs Guardians Prediction

I’ve been fading the Dodgers out of the gate and will continue to do so with these inflated lines. Long term the Dodgers will lose money. However, the Guardians aren’t hitting the ball right now and Williams didn’t look good in his season debut. Pitchers don’t find their footing against this Dodgers lineup. Yamamoto has become a trustworthy arm in the Dodgers’ rotation and looked solid in his first start. Yamamoto had a 3.04 ERA and a .205 allowed batting average at home last season. I’ll roll with the Dodgers and the RL in this spot.