Boston Red Sox (40-38) vs. San Francisco Giants (43-34)
June 22, 2025 4:05 pm EDT
The Line: San Francisco Giants -164 / Boston Red Sox 134; Over/Under: 7.5
(Get latest betting odds)
In this article, we will formulate a Giants vs Red Sox prediction for this MLB game on Sunday, June 22, at Oracle Park in San Francisco, California. Let’s take a look at the prediction for this MLB matchup.
Boston Red Sox Betting Preview
The Boston Red Sox (40-38, 18-21 Away) won ten of their last 13 games, their most fruitful period of the campaign. Boston beat the Yankees and Rays, swept the Yankees, and then defeated the Mariners on the road. The Red Sox opened this series in San Francisco with a 7-5 win, but lost the following one, 3-2. Brayan Bello took the loss after allowing three runs on four hits with six strikeouts and one walk in 6,0 innings.
This year, the Red Sox average 4.71 runs per game (8th in the MLB) on a .248/.322/.415 triple-slash. When it comes to pitching, the Red Sox’s staff has a 3.90 ERA (15th) and 1.30 WHIP (20th). Trevor Story leads the Red Sox with a .234 batting average, ten home runs, and 38 RBI this season.
The projected starting pitcher for the Red Sox is Lucas Giolito, who is 3-1 in nine starts this season, with a 4.73 ERA and 1.42 WHIP in 45.2 innings.
San Francisco Giants Betting Preview
The San Francisco Giants (43-34, 24-14 Home) were on a four-game losing run but managed to avoid the fifth in a row with a win over the Guardians. The Giants responded to a Game 1 loss to the Red Sox with a narrow, 3-2 victory on Saturday. Rafael Devers led the offense with a two-run homer, only six days after being traded from Boston to San Francisco. Landen Roupp got the win after allowing no runs on three hits with seven strikeouts and three walks across 6.0 innings of work.
This season, the Giants average 4.19 runs per game (20th in the MLB) on a .231/.312/.371 triple-slash. When it comes to pitching, the Giants’ staff has a 3.25 ERA (3rd) and 1.21 WHIP (8th). Wilmer Flores leads the Giants with a .255 batting average, 11 home runs, and 54 RBI this season.
Robbie Ray will take the mound for the Giants on Sunday. The 33-year-old left-hander has an 8-2 record in 15 starts this year with a 2.68 ERA and 1.12 WHIP in 87.1 innings.
Total Runs Facts
- Eight of the Giants’ last nine games as home favorites have gone UNDER the total runs line.
- Five of the Red Sox’s last six day games after playing the previous day have gone UNDER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Giants’ last nine games as favorites against AL East opponents.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Red Sox’s last five road games against National League opponents.
Matchup/League Facts
- The Giants rank 3rd in the league for ERA this season (3.25).
- The Giants rank 5th in the league for runs allowed this season (281).
- The Red Sox are one of only three teams in the league to rank top 10 in both steals and home runs this season.
- The Red Sox rank 5th in the league for hits this season (668).
Giants vs Red Sox Prediction
The teams have traded victories in the past couple of years, each recording five in the previous ten H2H encounters. Although these are not the teams you’d rely on when it comes to betting on the Over, I am going with Over in this one because of the low total (7.5). Also, I know that Giolito is not performing well in day games, so I’ll ignore the fact that he allowed no earned runs in his last two starts. Robbie Ray, on the other hand, surrendered multiple runs in his previous three starts. Go with Over.
