Guardians vs Astros Prediction 6/8/25 MLB Picks Today

The Houston Astros and the Cleveland Guardians meet Sunday in MLB action from PNC Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Guardians vs Astros Prediction.

Starting Pitching Matchup

The Houston Astros did not have a starting pitcher announced at the time that this article was posted. The Cleveland Guardians will send out Tanner Bibee for the start here, and Bibee is 4-6 with a 3.89 ERA and 56 strikeouts this season. This will be Bibee’s second career start against the Astros.

Houston Astros Recap

The Houston Astros come into this game looking to build on their 5-3 win over the Guardians from Saturday’s matchup to improve to 36-28 on the year. After this series, the Astros will head home for a series against the Chicago White Sox.

Astros Looking For Series Sweep After Third Straight Win

Jose Altuve has 64 hits, including 9 home runs and 24 RBIs. Jeremy Pena also has 79 hits with 12 homers and 32 RBIs with 13 stolen bases, while Yordan Alvarez has 4 doubles and 18 RBIs with 21 strikeouts as well. Jake Meyers has 11 doubles as well, and Christian Walker has also accrued a team-high 72 strikeouts so far this season. Altuve also has 5 stolen bases, while Jake Meyers has 8 stolen bases this season. Isaac Paredes also has a team-high 14 home runs with 38 RBIs of his own, and Cam Smith has contributed 3 homers and 18 RBIs.

Why the Houston Astros will win

• The Astros have won each of their last four games as underdogs.
• The Guardians have lost each of their last three games as favorites after going to extra innings.
• The Guardians have failed to cover the run line in each of their last 10 games as favorites after going to extra innings.
• The Astros have covered the run line in each of their last six games as underdogs.

Houston Astros Player Prop Facts

• Christian Walker has hit a home run in three of his four previous appearances with his team as an underdog against the Guardians.
• Jose Altuve has scored at least one run in each of his last seven appearances with the Astros as underdogs against the Guardians.
• Jose Altuve has recorded two or more hits in each of his last six appearances with the Astros as underdogs against the Guardians.
• Yordan Alvarez has recorded at least one RBI in each of his last six road appearances against AL opponents that held a winning record.
• Jose Altuve has recorded at least one Double in each of his last four appearances with the Astros as road underdogs against the Guardians.
• Jeremy Pena has recorded at least one Single in each of the Astros’ last 13 games against AL Central opponents.
• Jeremy Pena ranks 3rd in the league in Hits (79) this season.

Cleveland Guardians Recap

The Cleveland Guardians come into this game looking to rebound from their loss at the hands of the Astros on Saturday to slip to 33-30 on the year. After this series, the Guardians will square off against the Cincinnati Reds at home.

Guardians Drop Three In A Row

Steven Kwan leads the Guardians with 75 hits as part of a .314 batting average and 5 home runs, 14 doubles, and 21 RBIs. Kyle Manzardo has 39 hits with 6 doubles, 2 triples, 11 home runs, and 29 RBIs as well this year. Gabriel Arias has 12 doubles but also 66 strikeouts, and Manzardo has 59 strikeouts so far this season. Arias has also added 4 home runs and 25 RBIs, and Jose Ramirez has chipped in 12 home runs and 31 RBIs. Carlos Santana has also added 52 hits with 7 home runs and 29 RBIs this season.

Why the Cleveland Guardians will win

• The Astros have lost each of their last six games after going to extra innings.
• The Guardians have won each of their last eight Sunday home games against AL West opponents.
• The Guardians have covered the run line in each of their last eight Sunday day games against the Astros.
• The Astros have failed to cover the run line in six of their last seven day games following a road win.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit a home run in four of the Guardians’ last five games as home favorites.
• Jose Ramirez has recorded at least one RBI in each of the Guardians’ last four day games.
• Jose Ramirez has scored at least one run in each of the Guardians’ last four day games.
• Carlos Santana has recorded at least one hit in each of his last 12 appearances with his team as a home favorite against AL West opponents.
• Steven Kwan has recorded at least one Double in four of his last five appearances in day games against AL teams that held a winning record.
• Carlos Santana has recorded a Single in each of his last eight appearances with his team as a home favorite against AL West opponents.
• Jose Ramirez ranks T4th in the league in Hits (77) this season.

Total Runs Facts

• Each of the Astros’ last six day games against AL Central opponents have gone OVER the total runs line.
• Five of the Guardians’ last six games have gone UNDER the total runs line.

Guardians vs Astros Prediction

I’m on the Astros here. I get the case to be made for the Guardians at home, but Bibee hasn’t been pitching like a staff ace as of late and for much of the year. The Astros have been finding ways to get it done in this series. Cleveland’s got a solid lineup, but they haven’t been consistent with the offense, and I think the Astros can find a way to get the job done and complete the sweep here. Give me Houston in this one.