
Guardians vs Athletics Prediction 7-18-25 MLB Picks
Athletics (41-57) vs. Cleveland Guardians (46-49)
July 18, 2025 7:10 pm EDT
The Line: Cleveland Guardians -137 / Athletics +112; Over/Under: 8.5
(Get latest betting odds)
The Athletics and Cleveland Guardians meet Friday in MLB action at Progressive Field. Here’s a Guardians vs Athletics Prediction. This article will include a Guardians vs Athletics Pick.
Athletics Betting Preview
The Athletics are 41-57 on the year and play the Rangers, Astros, and Mariners next. The Athletics are batting .249 on the season, have a .316 OBP, and a .417 slugging percentage. The Athletics pitching staff has a 5.20 ERA and a 1.45 WHIP. Jacob Wilson leads the Athletics with 113 hits and 42 RBI, while Brent Rooker and Tyler Soderstrom have combined for 198 hits and 110 RBI.
JP Sears gets the ball for the Athletics, and he is 7-7 with a 4.79 ERA and 79 strikeouts this season. Sears is 0-3 with a 5.48 ERA and 20 strikeouts in his career against the Cleveland Guardians.
Cleveland Guardians Betting Preview
The Cleveland Guardians are 46-49 on the year and play the Orioles, Royals, and Rockies next. The Cleveland Guardians are batting .222 on the season, have a .294 OBP, and a .366 slugging percentage. The Cleveland Guardians pitching staff has a 3.92 ERA and a 1.34 WHIP. Steven Kwan leads the Cleveland Guardians with 103 hits and 32 RBI while Jose Ramirez and Carlos Santana have combined for 174 hits and 91 RBI.
Slade Cecconi gets the ball for the Cleveland Guardians, and he is 4-4 with a 3.44 ERA and 56 strikeouts this season. Cecconi is 1-0 with a 2.45 ERA and 10 strikeouts in his career against the Athletics.
Why the Cleveland Guardians will win
- The Athletics have lost each of their last seven games at Progressive Field.
- The Guardians have won nine of their last 10 home games against the Athletics.
- The Guardians have covered the run line in each of their last five games against AL West opponents.
- The Athletics have failed to cover the run line in each of their last four games at Progressive Field.
- The Guardians have led after 5 innings in each of their last four games against the Athletics at Progressive Field.
- The Guardians have led after 3 innings in five of their last six games against the Athletics.
Why the Athletics will win
- The Guardians have lost each of their last seven games at Progressive Field.
- The Athletics have won each of their last six road games against AL Central opponents that held a losing record.
- The Guardians have failed to cover the run line in each of their last nine games as favorites following an extra innings win.
- The Athletics have covered the run line in each of their last six games against American League opponents.
- The Guardians have trailed after 5 innings in 10 of their last 11 home night games.
- The Athletics have led after 3 innings in three of their last four games at Progressive Field against AL Central opponents that held a losing record.
Cleveland Guardians Player Prop Facts
- Jose Ramirez has hit a home run in each of the Guardians’ last four night games.
- Carlos Santana has recorded at least one hit in each of his last 13 appearances with his team as a home favorite against AL West opponents.
- Brayan Rocchio has recorded a Double in four of the Guardians’ last five night games.
- Jose Ramirez ranks T2nd in the league in Steals (29) this season.
Athletics Player Prop Facts
- Shea Langeliers has hit a home run in three of his last four road appearances with the Athletics against AL opponents.
- JP Sears has recorded four or more strikeouts in each of his last four appearances.
- Brent Rooker has recorded at least one hit in each of the Athletics’ last eight games as underdogs.
- Shea Langeliers has recorded a Double in each of his last three appearances against AL Central opponents.
- Jacob Wilson ranks T2nd in the league in Hits (112) this season.
Guardians vs Athletics Prediction
The Guardians should be favored at home where they’re the better team and Cecconi has been solid this season with a 3.44 ERA and 1.27 WHIP. However, Cecconi has a 4.95 ERA and .272 allowed batting average in 20 home innings. Also, Sears has allowed just nine hits and three runs in his last 16.2 innings, and his numbers are better on the road than at home this season. The Athletics have won three straight games Sears has pitched. I’ll take a shot with the A’s and the plus money on Friday night.