Guardians vs Orioles Prediction 7-23-25 MLB Picks

The Baltimore Orioles and Cleveland Guardians meet Wednesday in MLB action at Progressive Field. Here’s a Guardians vs Orioles Prediction. This article will include a Guardians vs Orioles Pick.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 44-56 on the year and play the Rockies, Blue Jays, and Cubs next. The Baltimore Orioles are batting .239 on the season, have a .303 OBP, and a .396 slugging percentage. The Baltimore Orioles pitching staff has a 5.02 ERA and a 1.43 WHIP. Gunnar Henderson leads the Baltimore Orioles with 98 hits and 35 RBI, while Jackson Holliday and Ryan O’Hearn have combined for 177 hits and 76 RBI.

Zach Eflin gets the ball for the Baltimore Orioles, and he is 6-5 with a 5.95 ERA and 42 strikeouts this season. Eflin is 1-1 with a 7.71 ERA and 6 strikeouts in his career against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 50-50 on the year and play the Royals, Rockies, and Twins next. The Cleveland Guardians are batting .225 on the season, have a .298 OBP, and a .373 slugging percentage. The Cleveland Guardians pitching staff has a 3.94 ERA and a 1.33 WHIP. Jose Ramirez leads the Cleveland Guardians with 107 hits and 56 RBI, while Steven Kwan and Carlos Santana have combined for 180 hits and 75 RBI.

Slade Cecconi gets the ball for the Cleveland Guardians, and he is 5-4 with a 3.84 ERA and 58 strikeouts this season. This will be Cecconi’s second career game against the Baltimore Orioles.

Why the Cleveland Guardians will win

• The Orioles have lost each of their last nine road games against AL Central opponents.
• The Guardians have won eight of their last nine games after playing the previous day.
• The Orioles have failed to cover the run line in each of their last seven games as underdogs against AL Central opponents.
• The home team has covered the run line in each of the last four games between the Orioles and Guardians.
• The Guardians have led after 3 innings in each of their last seven Wednesday games.
• The Guardians have led after 5 innings in 11 of their last 14 home games against AL East opponents that held a losing record.

Why the Baltimore Orioles will win

• The Guardians have failed to cover the run line in each of their last six Wednesday night games as favorites against American League opponents.
• The Orioles have covered the run line in eight of their last nine Wednesday games as road underdogs against AL Central opponents.
• The Guardians have trailed after 3 innings in four of their last five night games against AL East opponents that held a losing record.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit a home run in seven of the Guardians’ last eight night games.
• Jose Ramirez has recorded at least one hit in each of the Guardians’ last 11 home games against AL East opponents that held a losing record.
• Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites against AL opponents.
• Jose Ramirez ranks T3rd in the league in Steals (30) this season.

Baltimore Orioles Player Prop Facts

• Ramon Laureano has hit a home run in three of the Orioles’ last four games against the Guardians.
• Zach Eflin has recorded four or more strikeouts in three of his last four appearances with the Orioles as underdogs against AL opponents.
• Jorge Mateo has recorded a Double in four of his last five appearances against the Guardians.
• Ryan Mountcastle has recorded at least one hit in each of his last eight appearances against AL Central opponents.

Guardians vs Orioles Prediction

The Orioles look awful so far in the second half, and it’s highly unlikely Eflin turns things around. Eflin has a 5.95 ERA and 1.44 WHIP on the season, and he’s pitching for the first time in a month after dealing with a back issue. In 36 road innings, Eflin has a 6.25 ERA and .311 allowed batting average. The Guardians have won four of the last six games Cecconi has pitched, and they’re playing great ball this week overall. I want nothing to do with the O’s in this spot. Give me the Guardians and the more than reasonable price.