
Guardians vs Rangers Prediction 8/22/25 MLB Picks Today
Guardians vs Rangers
August 22, 2025 8:05 pm EDT
The Line: Guardians +142 / Rangers -158 / Over/Under: 7.5
(Get latest betting odds)
In this article, we will formulate a Guardians vs Rangers Prediction for this MLB game on Friday, August 22nd at the Globe Life Field in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.
Texas Rangers Preview
The Texas Rangers have a 63-66 record this season and are sitting on the third place of the AL West. The Rangers have a 37-26 home record and are 56-70 in over/under. They are coming off a 4-6 road defeat by the Royals, and are 2-7 in their last 9 games. Over is 6-2 in their last 8 games and are playing the Angels and the Athletics next.
The Rangers have a .233 batting average this season, .302 OBP and .377 slugging percentage. Texas’ pitching staff has a 3.48 ERA and 1.19 WHIP. Marcus Semien leads the Rangers with 108 hits, while Corey Seager is the team’s best hitter with a .269 batting average, adding a team-high 19 home runs. Adolis Garcia leads the team in RBI, with 64.
Nathan Eovaldi (R) is the projected starter for the Rangers, and he has a 11-3 record, 1.76 ERA and 0.87 WHIP.
Cleveland Guardians Preview
The Cleveland Guardians have a 64-62 record this season and are sitting on the third place of the AL Central. The Guardians have a 33-31 road record and are 59-63 in over/under. They are coming off a 2-3 road defeat by the Dbacks, and are 1-5 in their last 6 games. They are playing the Rays and the Mariners next.
The Guardians have a .227 batting average this season, .299 OBP and .374 Slugging percentage. Cleveland’s pitching staff has a 3.87 ERA and 1.31 WHIP. Jose Ramirez leads the Guardians with 135 hits, and he is the team’s best hitter with a .291 batting average. He also leads the team both in RBI, with 66, and in home runs with 26.
Slade Cecconi (R) is the projected starting pitcher for the Guardians, and he has a 5-6 record, 4.50 ERA and 1.32 WHIP.
Why the Texas Rangers will win
- The Rangers have won each of their last eight games as home favorites against American League opponents.
- The Guardians have lost five of their last six games.
- The Rangers have covered the run line each of their last six home games against American League opponents that held a winning record.
- The Rangers have led after 3 innings in three of their last four home games against American League opponents.
- The Rangers have led after 5 innings in each of their last four games as favorites.
Why the Cleveland Guardians will win
- The Guardians have won each of their last seven night games against American League opponents.
- The Rangers have lost each of their last four games as favorites.
- The Guardians have covered the run line in each of their last nine games against American League opponents following an extra innings loss.
- The Rangers have failed to cover the run line in each of their last six games at Globe Life Field.
- The Guardians have won the first inning in each of their last four night games against American League opponents that held a losing record.
- The Guardians have led after 3 innings in seven of their last eight games against AL West opponents.
- The Guardians have led after 5 innings in each of their last six night games against American League opponents that held a losing record.
Total Runs Facts
- Each of the Rangers’ last six games as favorites against AL Central opponents have gone UNDER the total runs line.
- Five of the Guardians’ last six games against AL West opponents have gone OVER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last six night games at Globe Life Field.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in 11 of the last 12 night games between the Guardians and Rangers.
Matchup/League Facts
- The Rangers rank 1st in the league for ERA this season (3.48).
- The Rangers rank 1st in the league for runs allowed this season (480).
- The Guardians rank 30th in the league for hits this season (938).
- The Guardians rank 30th in the league for batting average this season (.227).
Guardians vs Rangers Prediction
The Guardians are 7-2 in their last 9 meetings against the Rangers, but both teams are tied 2-2 wins in their last 4 meetings in Texas. Over is 6-4 in their last 10 meetings.
In this Guardians vs Rangers Prediction, the Rangers are coming as -170 home favorites. Eovaldi takes the mound for the Rangers, and he has been one of the best pitchers in baseball this season. On the flip side, Cecconi has been struggling for the Guardians lately, and has been torched in his last two starts, having given up 11 runs in 7.2 innings pitched. The Rangers also have a slightly better offense to offer Eovaldi run support, so this is a clear Rangers spot. Lay the juice and get the Texas Rangers to take care of business at home in this one.