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Guardians vs Twins Prediction 8-2-25 MLB Picks

Minnesota Twins (51-58) vs. Cleveland Guardians (55-54)
August 2, 2025 4:10 pm EDT
The Line: Cleveland Guardians / Minnesota Twins; Over/Under:
(Get latest betting odds)

The Minnesota Twins and Cleveland Guardians meet Saturday in MLB action at Progressive Field. Here’s a Guardians vs Twins Prediction. This article will include a Guardians vs Twins Pick.

Minnesota Twins Betting Preview

The Minnesota Twins are 51-58 on the year and play the Tigers, Royals, and Yankees next. The Minnesota Twins are batting .241 on the season, have a .312 OBP, and a .396 slugging percentage. The Minnesota Twins pitching staff has a 4.27 ERA and a 1.27 WHIP. Byron Buxton leads the Minnesota Twins with 92 hits and 59 RBI, while Carlos Correa and Ty France have combined for 178 hits and 75 RBI.

Bailey Ober gets the ball for the Minnesota Twins, and he is 4-6 with a 5.28 ERA and 74 strikeouts this season. Ober is 3-2 with a 2.10 ERA and 51 strikeouts in his career against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 55-54 on the year and play the Mets, White Sox, and Marlins next. The Cleveland Guardians are batting .228 on the season, have a .301 OBP, and a .375 slugging percentage. The Cleveland Guardians’ pitching staff has a 3.86 ERA and a 1.31 WHIP. Jose Ramirez leads the Cleveland Guardians with 119 hits and 57 RBI, while Steven Kwan and Carlos Santana have combined for 199 hits and 84 RBI.

Tanner Bibee gets the ball for the Cleveland Guardians, and he is 7-9 with a 4.39 ERA and 107 strikeouts this season. Bibee is 2-0 with a 2.51 ERA and 50 strikeouts in his career against the Minnesota Twins.

Why the Cleveland Guardians will win

  • The Guardians have won each of their last nine day games against the Twins following a win.
  • The Twins have lost eight of their last nine road games after going to extra innings.
  • The Guardians have covered the run line in each of their last nine day games against the Twins following a win.
  • The Twins have failed to cover the run line in each of their last seven day games against AL Central opponents.
  • The Twins have trailed after 5 innings in each of their last six games.
  • The Twins have lost the first inning in five of their last six day games at Progressive Field.
  • The Guardians have led after 3 innings in each of their last six day games against the Twins at Progressive Field.

Why the Minnesota Twins will win

  • The Guardians have lost five of their last six day games at Progressive Field following an extra-innings win.
  • The Twins have won five of their last six games following a road loss.
  • The road team has covered the run line in eight of the Twins’ last nine games.
  • The Guardians have failed to cover the run line in each of their last four games against American League opponents following a win.
  • The Guardians have trailed after 5 innings in each of their last three day games against AL Central opponents that held a losing record.

Cleveland Guardians Player Prop Facts

  • Will Brennan has recorded at least one hit in each of his last nine appearances against the Twins.
  • Carlos Santana has hit a home run in two of the Guardians’ last three games against the Twins.

Minnesota Twins Player Prop Facts

  • Trevor Larnach has recorded at least one hit in each of the Twins’ last six day games against AL opponents that held a winning record.
  • James Outman has hit a home run in three of his last four appearances in day games against AL teams that held a winning record.

Guardians vs Twins Prediction

The Twins continue to pile up the losses, and Ober isn’t the pitcher to turn things around. Ober has a 5.28 ERA and 1.41 WHIP, and he hasn’t pitched in a month due to a hip injury. The Twins have lost seven straight games Ober has pitched. The Twins haven’t won a game with Ober on the mound since May 19. Bibee has issues as well, and he’s coming off a July where he allowed 29 hits and 18 earned runs in 26.1 innings. Still, the Guardians are playing the better ball. Give me the Guardians.

Randy Chambers's Free Pick: Cleveland Guardians

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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