Los Angeles Angels vs Boston Red Sox Prediction 05-22-2023 MLB Picks

Chris RuffoloMay 22, 2023
Los Angeles Angels vs Boston Red Sox Prediction 05-22-2023 MLB Picks player photo
Credit: USA Today Sports

The Boston Red Sox and the Los Angeles Angels meet in MLB action from Angel Stadium on Monday. Let’s dive into the odds, starting pitching matchup, history and make a prediction for this game.


Los Angeles is a -115 home favorite while Boston is a -105 road underdog. The total for this game is set at 9.5 runs.

Starting Pitching Matchup

Tanner Houck will start for the Red Sox and is 3-3 with a 5.48 ERA and 38 strikeouts this season. Jaime Barria will start for the Angels and is 1-1 with a 1.96 ERA and 21 strikeouts this season.

Matchup History

Los Angeles’ 5-4 win back on April 17th, 2023, snapped Boston’s three-game win streak in this head-to-head matchup.


Boston is 5-2 in their last 7 road games and 36-16 in their last 52 games against the AL West while the over is 4-1-1 in their last 6 series-opening games. Los Angeles is 2-5 in their last 7 home games and 1-5 in their last 6 games following a win while the under is 4-1 in their last 5 home games.


I’m backing the Red Sox here. I wasn’t the biggest fan of this pitching matchup, but Houck has actually pitched fairly well on the road, while Barria is a bullpen arm making a spot start and from what I remember with Barria, he didn’t fare overly well in those starts. The Red Sox still have a potent offense that’s fully capable of doing damage, and I think they take it to the Angels and their pitching staff here. Wouldn’t surprise me if we had a high-scoring game, but I’ll take the Red Sox for the win.

Chris Ruffolo's Free Pick:Boston -105
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Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg