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Mariners vs Brewers Prediction 7-21-25 MLB Picks Today

Milwaukee Brewers (59-40) vs. Seattle Mariners (53-46)
July 21, 2025 9:40 pm EDT
The Line: Seattle Mariners -127 / Milwaukee Brewers 104; Over/Under: 7
(Get latest betting odds)

In this article, we will formulate a Mariners vs Brewers prediction for this MLB game on Monday, July 21, at T-Mobile Park in Seattle, Washington. Let’s take a look at the prediction for this MLB matchup.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers (59-40, 26-23 Away) are undoubtedly the hottest team in the MLB right now. They are on a 10-game winning streak, sweeping the Dodgers twice and the Nationals during this period. Milwaukee swept the Dodgers on the road to open the second half and clinched the series with a 6-5 victory on Sunday. Isaac Collins led the offense with two RBI, while Jose Quintana got the win after allowing four runs on four hits with five strikeouts and no walks in 6.0 innings.

This season, the Brewers average 4.78 runs per game (7th in the MLB) on a .250/.325/.385 triple-slash. When it comes to pitching, the Brewers’ staff has a 3.66 ERA (7th) and 1.24 WHIP (11th). Christian Yelich leads the Brewers with a .259 batting average, 19 home runs, and 65 RBI this season.

Brandon Woodruff will take the mound for the Brewers on Monday. The 32-year-old right-hander has a 1-0 record in two starts this year with a 2.61 ERA and 0.68 WHIP in 10.1 innings.

Seattle Mariners Betting Preview

The Seattle Mariners (53-46, 27-22 Home) ended the first half with a sweep of the Detroit Tigers and opened the second half with a win over the Houston Astros. The Mariners were hoping to sweep the Astros as well after winning the opening two games, but fell to an 11-3 defeat on Sunday. Jorge Polanco led the offense with two RBI, while Bryan Woo took the loss after allowing five runs (four earned) on six hits with six strikeouts and one walk.

This year, the Mariners average 4.72 runs per game (8th in the MLB) on a .249/.326/.415 triple-slash. When it comes to pitching, the Mariners’ staff has a 3.92 ERA (16th) and 1.26 WHIP (17th). Cal Raleigh leads the Mariners with a .256 batting average, 38 home runs, and 83 RBI this season.

The projected starting pitcher for the Mariners is George Kirby, who is 4-4 in ten starts this season, with a 4.50 ERA and 1.15 WHIP in 54.0 innings.

Total Runs Facts

  • Eight of the Mariners’ last nine home games against NL Central opponents have gone UNDER the total runs line.
  • Five of the Brewers’ last six games have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Brewers’ last eight road games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Mariners’ last five home games.

Matchup/League Facts

  • The Mariners rank 27th in the league for strikeouts against this season (878).
  • The Mariners rank 26th in the league for doubles this season (142).
  • The Brewers are one of only five teams in the league to rank top 10 in both strikeouts and on-base percentage this season.
  • The Brewers rank 5th in the league for opponent batting average this season (.232).

Mariners vs Brewers Prediction

The Brewers won seven of the previous ten H2H encounters, including six of the last seven. Four of the last six meetings went Over, and considering the low total (6.5) for this game, I am going with another Over. Brandon Woodruff returned recently from the IL and pitched well, but Seattle is playing very well lately and will cause him problems. George Kirby, on the other hand, has been pretty solid in June and in two starts in July, but he has to deal with the hottest team in baseball. Go with Over.

Oliver Zivic's Free Pick: Over 6.5

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Oliver Zivic

Professional journalist and expert bettor with 20+ years of experience. I cover Football (soccer), NFL, NBA, NHL, MLB, CFB, and CBB.

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