Mariners vs Nationals Prediction 5/28/25 MLB Picks Today

The Washington Nationals and Seattle Mariners meet Wednesday in MLB action at T-Mobile Park. Here’s a Mariners vs Nationals Prediction. This article will include a Mariners vs Nationals Pick.

Washington Nationals Betting Preview

The Washington Nationals are 24-30 on the year and play the Diamondbacks, Cubs, and Rangers next. The Washington Nationals are batting .239 on the season, have a .306 OBP, and a .385 slugging percentage. The Washington Nationals’ pitching staff has a 5.14 ERA and a 1.42 WHIP. James Wood leads the Washington Nationals with 58 hits and 37 RBI, while Keibert Ruiz and CJ Abrams have combined for 96 hits and 39 RBI.

Trevor Williams gets the ball for the Washington Nationals, and he is 2-5 with a 6.39 ERA and 41 strikeouts this season. Williams is 0-0 with a 4.00 ERA and 12 strikeouts in his career against the Seattle Mariners.

Seattle Mariners Betting Preview

The Seattle Mariners are 30-23 on the year and play the Twins, Orioles, and Angels next. The Seattle Mariners are batting .239 on the season, have a .327 OBP, and a .402 slugging percentage. The Seattle Mariners’ pitching staff has a 3.64 ERA and a 1.31 WHIP. Julio Rodriguez leads the Seattle Mariners with 52 hits and 32 RBI, while Cal Raleigh and JP Crawford have combined for 96 hits and 57 RBI.

George Kirby gets the ball for the Seattle Mariners, and he is 0-1 with a 12.27 ERA and 4 strikeouts this season. Kirby is 0-1 with a 4.15 ERA and 12 strikeouts in his career against the Washington Nationals.

Why the Seattle Mariners will win

• The Mariners have won each of their last six games against National League opponents.
• The Nationals have lost eight of their last nine games against American League opponents that held a winning record.
• The Nationals have failed to cover the run line in seven of their last eight games against American League opponents that held a winning record.
• The Mariners have covered the run line in each of their last seven Wednesday home games.
• The Nationals have trailed after 5 innings in 11 of their last 12 road night games.
• The Mariners have led after 3 innings in each of their last seven games against NL East opponents.
• The Mariners have won the first inning in four of their last five night games against NL East opponents that held a losing record.

Why the Washington Nationals will win

• The Mariners have lost four of their last five games as favorites following a win.
• The Nationals have won four of their last five games as underdogs against AL West opponents following a loss.
• The Nationals have covered the run line in each of their last 10 games against AL West opponents following a road loss.
• The Mariners have failed to cover the run line in 10 of their last 11 games as favorites after playing the previous day.
• The Mariners have trailed after 5 innings in three of their last four night games.

Seattle Mariners Player Prop Facts

• Cal Raleigh has hit at least one home run in four of the Mariners’ last five games against NL opponents.
• Cal Raleigh has recorded at least one RBI in each of the Mariners’ last five games against NL opponents.
• J.P. Crawford has scored at least one run in each of the Mariners’ last seven night games against NL East opponents that held a losing record.
• George Kirby has recorded six or more strikeouts in five of his last six home appearances against opponents that held a losing record.
• J.P. Crawford has recorded at least one Single in each of the Mariners’ last eight games as favorites against NL opponents.
• Jorge Polanco has recorded at least one hit in each of his last nine home appearances against NL East opponents that held a losing record.
• George Kirby has recorded a win in each of his last five appearances against opponents that held a losing record.
• Cal Raleigh ranks 2nd in the league in Home Runs (19) this season.

Washington Nationals Player Prop Facts

• Nathaniel Lowe has hit a home run in two of his last three appearances against AL West opponents.
• Trevor Williams has recorded a win in six of his last seven appearances in night games against teams that held a winning record.
• Luis Garcia has recorded at least one RBI in four of his last five road appearances after playing the previous day.
• Trevor Williams has recorded five or more strikeouts in three of his last four appearances with the Nationals as underdogs against AL opponents.
• Nathaniel Lowe has recorded at least one Single in each of his last six appearances in night games against AL West teams that held a winning record.
• Amed Rosario has recorded a Double in four of his last five appearances against opponents that held a winning record.
• Amed Rosario has recorded at least one hit in each of his last nine appearances with the Nationals as underdogs.
• Paul DeJong has scored a run in four of his last five appearances against AL West opponents that held a winning record.
• James Wood ranks T8th in the league in Home Runs (14) this season.

Mariners vs Nationals Prediction

The Nationals haven’t scored more than three runs in each of their last four games, and now they’re throwing out Williams, who has allowed 25 hits and 16 earned runs in his last 19.1 innings. Williams is allowing a .305 batting average on the season, and he’s giving up a 6.29 ERA and .333 allowed batting average in 24.1 road innings. Kirby was rocked in his season opener, but he’s pitched just 3.2 innings this season. The jury is still out on Kirby. The Nationals are a tough sell in this spot. I’ll side with the Mariners and the RL for max betting value.