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Mariners vs Orioles Prediction 6/4/25 MLB Picks Today

Baltimore Orioles (23-36) vs. Seattle Mariners (32-27)
June 4, 2025 9:40 pm EDT
The Line: Seattle Mariners -130 / Baltimore Orioles 110; Over/Under: 8.5
(Get latest betting odds)

In this article, we will formulate a Mariners vs Orioles prediction for this MLB game on Wednesday, June 4, at T-Mobile Park in Seattle, Washington. Let’s take a look at the prediction for this MLB matchup.

Baltimore Orioles Betting Preview

The Baltimore Orioles (23-36, 11-19 Away) bounced back from a series loss to the Cardinals with a sweep of the Chicago White Sox. Following a 5-1 win in Game 1 of the series against the Seattle Mariners, the Orioles have four straight wins for the first time this season. Tomoyuki Sugano got the win after allowing one run on five hits with five strikeouts and one walk across 7.0 innings of work.

This year, the Orioles average 3.83 runs per game (25th in the MLB) on a .237/.302/.385 triple-slash. When it comes to pitching, the Orioles’ staff has a 5.27 ERA (28th) and 1.46 WHIP (27th). Cedric Mullins leads the Orioles with a .232 batting average, ten home runs, and 31 RBI this season.

The projected starting pitcher for the Orioles is Cade Povich, who is 1-4 in ten starts this season, with a 5.29 ERA and 1.53 WHIP in 51.0 innings.

Seattle Mariners Betting Preview

The Seattle Mariners (32-27, 16-15 Home) lost a series to the Astros and Nationals, but bounced back with a win over the Twins despite losing Game 1. The Mariners also lost Game 1 of the current series against the Orioles. George Kirby took the loss after allowing two runs on eight hits with three strikeouts and one walk in 5.0 innings.

This season, the Mariners average 4.53 runs per game (10th in the MLB) on a .237/.321/.396 triple-slash. When it comes to pitching, the Mariners’ staff has a 3.86 ERA (14th) and 1.32 WHIP (20th). Cal Raleigh leads the Mariners with a .259 batting average, 23 home runs, and 45 RBI this season.

Emerson Hancock will take the mound for the Mariners on Wednesday. The 26-year-old right-hander has a 2-2 record in nine starts this year with a 5.64 ERA and 1.57 WHIP in 44.2 innings.

Total Runs Facts

  • Eight of the Orioles’ last nine night games against American League opponents have gone UNDER the total runs line.
  • Five of the Mariners’ last six games as favorites against AL East opponents have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Orioles’ last four road games against AL West opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the last six games between the Orioles and Mariners at T-Mobile Park.

Matchup/League Facts

  • The Mariners rank T27th in the league for triples this season (3).
  • The Mariners rank T5th in the league for walks this season (219).
  • The Orioles rank 28th in the league for opponent batting average this season (.271).
  • The Orioles rank 28th in the league for hits allowed this season (548).

Mariners vs Orioles Prediction

The Orioles won seven of the previous ten H2H encounters, including four of the last five. I am not impressed with Cade Povich and Emerson Hancock this season, which is the main reason I am going with Over in this game. Povich allowed multiple runs in four of his last five starts, while Hancock surrendered multiple runs in all but one start this season. I am backing both offenses to score 3+ runs in the opening five innings.

Oliver Zivic's Free Pick: Over 8.5

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Oliver Zivic

Professional journalist and expert bettor with 20+ years of experience. I cover Football (soccer), NFL, NBA, NHL, MLB, CFB, and CBB.

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