Marlins vs Nationals Prediction 9/10/25 MLB Picks Today

The Miami Marlins and Washington Nationals meet on Thursday in MLB action from LoanDepot Park. Here’s a Marlins vs Nationals prediction. We will look at this from a betting perspective and determine the best Marlins vs Nationals pick.

Nationals Weren’t Clutch

The Nationals weren’t clutch on Wednesday, and that was the difference as they were defeated 8-3. The Nationals scored two runs in the 6th inning, but that was the only strong offensive game, and that was the difference. Jake Irvin was on the mound, and he went five innings, giving up five hits and three runs. Jackson Ruetledge went 1.1 innings, giving up three hits and two runs. 

The Nationals are averaging 4.33 runs while their pitching is giving up 5.45 runs per game. The offense is ranked 18th while the pitching is ranked 29th. They have a negative run differential of -1.13. James Wood has hit 27 home runs and driven in 88 RBIs so far this season. MacKenzie Gore is getting the start and he sits with a 5-13 record and an ERA of 4.15. Against the New York Yankees in his last start he went five innings giving up three hits and three runs. 

Why the Nationals Will Beat the Marlins

• The Marlins have lost eight of their last nine night games following a win.
• The Nationals have won six of their last seven games against National League opponents that held a losing record.
• The Marlins have failed to cover the run line in eight of their last nine night games following a win.
• The Nationals have covered the run line in seven of their last eight games after playing the previous day.
• The Nationals have led after 5 innings in each of their last six games against opponents that held a losing record.
• The Nationals have led after 3 innings in five of their last six games against opponents that held a losing record.

Marlins Offense Impressed

The Marlins offense sure impressed on Wednesday, putting up eight runs on the way to the victory. Xavier Edwards had a huge game hitting a home run and driving in three RBIs. He also had three hits and three runs. Otto Lopez also finished with two hits and two RBIs. Eury Perez was on the mound and he threw 5.2 innings, giving up seven hits and three runs. The Marlins are going to need the offense to put on a show early in this game. Getting a lot start could be a major issue here. 

The Marlins are averaging 4.31 runs while their pitching is giving up 5.09 runs per game. The offense is ranked 17th while the pitching is ranked 26th. Ryan Weathers is going to get the start for the Marlins, and he sits with a 1-1 record and an ERA of 3.28. Against the Tampa Bay Rays in his last appearance, he went three inning,s giving up three hits and four runs. He gave up one home run. On Friday, the Marlins continue their home stretch with a game against the Detroit Tigers.

Why the Marlins Will Beat the Nationals

• The Nationals have lost each of their last five night games following a road loss.
• The Marlins have won five of their last six night games against the Nationals at LoanDepot Park following a home win.
• The Nationals have failed to cover the run line in each of their last five night games following a road loss.

Miami Marlins vs Washington Nationals Prediction

The Marlins dominated on Wednesday, and it’s going to be much of the same here. Ryan Weathers has been impressive this season and he sits with an ERA of 3.28.  Gore gave up three runs in his last start, and the Marlins offense has all kinds of confidence right now. The long ball is going to be flying out for Miami, and that is going to be enough for the home team to come out ahead. Back the Marlins on the money line to cash here.