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Milwaukee Brewers vs Chicago Cubs Prediction 7-29-25 Picks

Chicago Cubs (62-44) vs. Milwaukee Brewers (63-43)
July 29, 2025 11:40 pm EDT
The Line: Milwaukee Brewers -119 / Chicago Cubs -102; Over/Under: 8.5
(Get latest betting odds)

The Chicago Cubs and the Milwaukee Brewers meet Tuesday in MLB action from American Family Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago Cubs vs. Milwaukee Brewers prediction.

Starting Pitching Matchup

The Chicago Cubs will send out Colin Rea for the start here, and Rea is 8-4 with a 4.06 ERA and 73 strikeouts this season. This will be Rea’s second career start against the Brewers. Quinn Priester will get the nod for the Brewers here and is 9-2 with a 3.28 ERA and 86 strikeouts this season. This will be Priester’s first career start against the Cubs.

Chicago Cubs Recap

The Chicago Cubs come into this game looking to bounce back from an 8-4 loss at the hands of the Brewers on Monday to sit at 62-44 on the year. After this series, the Cubs will head home for a series against the Orioles.

Cubs Looking For A Bounce Back

Ian Happ has 85 hits with 16 doubles, 14 home runs, and 49 RBIs. Kyle Tucker has 105 hits, including 20 doubles, 4 triples, 18 home runs, and 58 RBIs, while Seiya Suzuki also has 101 hits with 24 doubles and 26 home runs and 81 RBIs of his own. Pete Crow-Armstrong also has contributed 109 hits, 28 doubles, 4 triples, 27 home runs, and 76 RBIs this season. Dansby Swanson has added 16 home runs and 49 RBIs, while also having 120 strikeouts, and Suzuki has 119 strikeouts so far this season. Crow-Armstrong also has a team-high 29 stolen bases, while Nico Hoerner has 19 stolen bases this season. Tucker’s also added 23 stolen bases while Michael Busch has also chipped in 15 doubles, 3 triples, 20 home runs, and 60 RBIs this season.

Why the Chicago Cubs will win

  • The Cubs have won nine of their last 10 games as underdogs against National League opponents following a road loss.
  • The Brewers have lost three of their last four games as favorites against NL Central opponents following a win.
  • The Cubs have covered the run line in each of their last 13 games as underdogs against National League opponents following a road loss.
  • The Brewers have failed to cover the run line in each of their last nine games as home favorites against NL Central opponents following a win.

Chicago Cubs Player Prop Facts

  • Ian Happ has recorded a Double in each of the Cubs’ last five games as road underdogs against NL Central opponents.
  • Kyle Tucker has hit a home run in five of the Cubs’ last nine games as underdogs against NL opponents.
  • Nico Hoerner has recorded at least one hit in each of the Cubs’ last 13 road games against NL Central opponents that held a winning record.
  • Kyle Tucker ranks 4th amongst qualified players for On Base Percentage (.386) this season.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to build on their win over the Cubs on Monday to sit at 63-43 on the year. After this series, the Brewers will take to the road for a set against the Washington Nationals.

Brewers Post Back-To-Back Wins

Brice Turang has 105 hits with 6 home runs, 43 RBIs and 19 stolen bases while Jackson Chourio has 121 hits with a team-high 29 doubles, 18 stolen bases, 17 home runs and 67 RBIs and Sal Frelick has 102 hits as well as 3 triples, 7 home runs, 39 RBIs and 17 stolen bases so far this season. Christian Yelich also has 15 stolen bases with 19 homers and 66 RBIs while also adding 11 doubles. Yelich also has a team-high 115 strikeouts up to this point in the year. William Contreras has 6 homers and 42 RBIs as well this season. Rhys Hoskins has added 65 hits with 12 home runs, 42 RBIs, and 12 doubles.

Why the Milwaukee Brewers will win

  • The Brewers have won each of their last 10 night games at American Family Field following a home win.
  • The Cubs have lost five of their last six games at American Family Field against NL Central opponents that held a winning record.
  • The Brewers have covered the run line each of their last 11 games against teams that held a winning record.
  • The Cubs have failed to cover the run line in five of their last six games at American Family Field against teams that held a winning record.

Milwaukee Brewers Player Prop Facts

  • Sal Frelick has hit a home run in each of his last two appearances in night games against NL teams that held a winning record.
  • Andrew Vaughn has recorded a Double in three of his four previous appearances against NL Central opponents at American Family Field.
  • Andrew Vaughn has recorded at least one hit in each of his last 15 home appearances against NL opponents.
  • Jackson Chourio ranks T5th in the league in Hits (121) this season.

Total Runs Facts

  • Each of the Cubs’ last four games against NL Central opponents have gone OVER the total runs line.
  • Four of the Brewers’ last five games against NL Central opponents have gone OVER the total runs line.

Chicago Cubs vs. Milwaukee Brewers Prediction

I’m on the Brewers here. I get the case to be made for the Cubs here, but the thing is that the Brewers have been winning a ton of Quinn Priester’s starts this year and while the Cubs are still a solid lineup, I’m not much of a Colin Rea fan and at the end of the day, the Brewers for me have the better bullpen. I’ll roll with Milwaukee in this one.

Chris Ruffolo's Free Pick: Milwaukee Brewers -119

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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