Brewers vs Angels Prediction 9/16/25 MLB Picks Today

The Los Angeles Angels and the Milwaukee Brewers meet Tuesday in MLB action from American Family Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Brewers vs Angels Prediction.

Starting Pitching Matchup

The Los Angeles Angels will start Caden Dana here and Dana is 0-1 with a 6.32 ERA and 19 strikeouts this season. This will be Dana’s first career start against the Brewers. Freddy Peralta will get the start for the Brewers here and Peralta is 16-6 with a 2.69 ERA and 185 strikeouts this season. In his career, Peralta is 1-0 with a 6.75 ERA and 13 strikeouts against the Angels.

Los Angeles Angels Recap

The Los Angeles Angels come into this game looking to rebound from their 11-2 loss at the hands of the Seattle Mariners last time out to sit at 69-81 this season. After this series, the Angels will head on the road for a series against the Colorado Rockies.

Angels Drop Four In A Row

Logan O’Hoppe has 85 hits including 19 home runs and 43 RBIs while Nolan Schanuel has 123 hits with 22 doubles, a triple, 10 home runs and 49 RBIs. Luis Rengifo has 15 doubles with his 115 hits and Taylor Ward also has 120 hits as well while Mike Trout’s added 21 home runs and 58 RBIs so far this season. Jo Adell has 35 home runs and 94 RBIs. Ward has also chipped in 31 doubles, 30 home runs and 97 RBIs but has a team-high 158 strikeouts while Zach Neto has 29 doubles, 26 home runs, 62 RBIs and 26 stolen bases.

Why the Los Angeles Angels will win

• The Brewers have lost each of their last four games as favorites against American League opponents.
• The Angels have won 12 of their last 16 games as road underdogs against National League opponents following a loss.
• The underdogs have covered the run line in eight of the Brewers’ last nine games at American Family Field.
• The Brewers have failed to cover the run line in each of their last five games as favorites against American League opponents.

Los Angeles Angels Player Prop Facts

• Mike Trout has recorded at least one hit in each of his last 10 Tuesday appearances with the Angels as underdogs.
• Travis d’Arnaud has hit at least one home run in each of his last two road appearances against the Brewers.
• Jo Adell ranks 8th in the league in Home Runs (36) this season.

Milwaukee Brewers Recap

The Milwaukee Brewers will be out to rebound from their 3-2 loss at the hands of the St. Louis Cardinals last time out to sit at 91-59 this season. After this series, the Brewers will head on the road for a series rematch with the Cardinals.

Brewers Looking To Build On Series Win

Brice Turang has 156 hits with 18 home runs, 75 RBIs and 24 stolen bases while Jackson Chourio has 139 hits with a team-high 33 doubles, 18 stolen bases, 20 home runs and 75 RBIs and Sal Frelick has 145 hits as well as 3 triples, 10 home runs, 57 RBIs and 19 stolen bases so far this season. Christian Yelich also has 16 stolen bases with 28 homers and 96 RBIs while also adding 18 doubles. Yelich also has a team-high 157 strikeouts up to this point in the year. William Contreras has 17 homers and 74 RBIs as well this season. Joey Ortiz has chipped in 100 hits with 17 doubles, 7 home runs and 44 RBIs and Caleb Durbin also has 24 doubles with 11 homers and 49 RBIs. 

Why the Milwaukee Brewers will win

• The Brewers have won each of their last 11 Tuesday home games.
• The Angels have lost each of their last five road games.
• The Brewers have covered the run line in eight of their last nine night games following a home loss.
• The Angels have failed to cover the run line in seven of their last eight night games against NL Central opponents.

Milwaukee Brewers Player Prop Facts

• Christian Yelich has hit at least one home run in three of his last four appearances after not playing the previous day.
• Freddy Peralta has recorded a win in seven of his last eight appearances in night games.
• Sal Frelick has recorded at least one hit in each of his last 10 appearances with the Brewers as home favorites against AL opponents.
• Rhys Hoskins has recorded a Double in each of the Brewers’ last three home games against AL West opponents.
• Freddy Peralta ranks T2nd in the league for Wins (16) this season.

Total Runs Facts

• Six of the Brewers’ last seven night games against AL West opponents have gone UNDER the total runs line.
• Four of the Angels’ last five games as underdogs have gone OVER the total runs line.

Brewers vs Angels Prediction

I’m on the Brewers in this one. I just don’t see Caden Dana as the type of pitcher to be able to match zeroes with the Brewers and Freddy Peralta in this matchup. Furthermore, I think it’s going to be a lot easier for the Brewers to break through and get the job done in this series, especially in the opener against Dana. He has had a history of struggling in the starters’ role. I’ll roll with Milwaukee here.