Brewers vs Angels Prediction 9/18/25 MLB Picks Today
LA Angels (69-83) vs. Milwaukee Brewers (93-59)
September 18, 2025 7:40 pm EDT
The Line: Milwaukee Brewers -194 / LA Angels +157; Over/Under: 8
(Get latest betting odds)
The Los Angeles Angels and the Milwaukee Brewers meet Thursday in MLB action from American Family Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Brewers vs Angels Prediction.
Starting Pitching Matchup
The Los Angeles Angels will start Yusei Kikuchi here and Kikuchi is 6-11 with a 4.08 ERA and 166 strikeouts this season. In his career, Kikuchi is 2-1 with a 3.00 ERA and 14 strikeouts against the Brewers. The Milwaukee Brewers will start Quinn Priester here and Priester is 13-2 with a 3.25 ERA and 118 strikeouts this season. This will be Priester’s second career start against the Angels.
Los Angeles Angels Recap
The Los Angeles Angels come into this game looking to rebound from their 9-2 loss at the hands of the Brewers in Wednesday’s matchup to sit at 69-83 this season. After this series, the Angels will head on the road for a series against the Colorado Rockies at Coors Field.
Angels Drop 6 In A Row
Logan O’Hoppe has 85 hits including 19 home runs and 43 RBIs while Nolan Schanuel has 123 hits with 22 doubles, a triple, 10 home runs and 49 RBIs. Luis Rengifo has 15 doubles with his 115 hits and Taylor Ward also has 120 hits as well while Mike Trout’s added 21 home runs and 58 RBIs so far this season. Jo Adell has 35 home runs and 94 RBIs. Ward has also chipped in 31 doubles, 30 home runs and 97 RBIs but has a team-high 158 strikeouts while Zach Neto has 29 doubles, 26 home runs, 62 RBIs and 26 stolen bases.
Why the Los Angeles Angels will win
- The Brewers have lost five of their last seven games as home favorites after playing the previous day.
- The Angels have won 12 of their last 18 games as road underdogs against National League opponents following a loss.
- The Brewers have failed to cover the run line in seven of their last eight home games following a win.
Los Angeles Angels Player Prop Facts
- Yusei Kikuchi has recorded five or more strikeouts in 12 of his last 13 road appearances against NL opponents.
- Travis d’Arnaud has hit at least one home run in each of his last two road appearances against the Brewers.
- Zach Neto has recorded at least one hit in each of his last 10 Thursday night appearances.
- Jo Adell ranks 8th in the league in Home Runs (36) this season.
Milwaukee Brewers Recap
The Milwaukee Brewers will be out to add on to their victory over the Angels from Wednesday’s matchup to sit at 93-59 this season. After this series, the Brewers will head on the road for a division series rematch against the St. Louis Cardinals.
Brewers Win 7th In Last 11 Tries
Brice Turang has 156 hits with 18 home runs, 75 RBIs and 24 stolen bases while Jackson Chourio has 139 hits with a team-high 33 doubles, 18 stolen bases, 20 home runs and 75 RBIs and Sal Frelick has 145 hits as well as 3 triples, 10 home runs, 57 RBIs and 19 stolen bases so far this season. Christian Yelich also has 16 stolen bases with 28 homers and 96 RBIs while also adding 18 doubles. Yelich also has a team-high 157 strikeouts up to this point in the year. William Contreras has 17 homers and 74 RBIs as well this season. Joey Ortiz has chipped in 100 hits with 17 doubles, 7 home runs and 44 RBIs and Caleb Durbin also has 24 doubles with 11 homers and 49 RBIs.
Why the Milwaukee Brewers will win
- The home team has won each of the Angels’ last eight games.
- The Angels have lost each of their last seven road games.
- The Angels have failed to cover the run line in each of their last eight night games against NL Central opponents following a loss.
- The Brewers have covered the run line in eight of their last nine night games against AL West opponents that held a losing record.
Milwaukee Brewers Player Prop Facts
- Andrew Vaughn has hit a home run in two of his last three appearances with his team as a home favorite against AL opponents.
- Sal Frelick has recorded at least one hit in each of his last 12 appearances with the Brewers as home favorites against AL opponents.
- Andrew Vaughn has recorded at least one Double in each of his last three appearances with his team as a favorite against the Angels.
- Quinn Priester ranks T9th in the league for Wins (13) this season.
Total Runs Facts
- Seven of the Angels’ last eight night games after playing the previous day have gone OVER the total runs line.
- Each of the Brewers’ last four games against American League opponents have gone OVER the total runs line.
Brewers vs Angels Prediction
I’m backing the Angels here. The Angels just look like a team that’s playing out the string at this point, and I think the Brewers are just finding themselves at the right time of year. I think that the Brew Crew pile on once again here. The Angels have just been overmatched in the first two games, and I look for more of the same here. Give me Milwaukee.

