Brewers vs Giants Prediction 8/22/25 MLB Picks Today

The San Francisco Giants and the Milwaukee Brewers meet Friday in MLB action from American Family Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Brewers vs Giants Prediction.

Starting Pitching Matchup

The San Francisco Giants will send out Carson Whisenhunt for the start here and Whisenhunt is 1-1 with a 5.02 ERA and 12 strikeouts this season. This will be Whisenhunt’s first career start against the Brewers. The Milwaukee Brewers will trot out Jose Quintana for the start and Quintana is 10-4 with a 3.32 ERA and 73 strikeouts this season. In his last five starts against the Giants, Quintana is 2-2 with a 4.39 ERA and 21 strikeouts.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to rebound from an 8-4 loss at the hands of the San Diego Padres last time out to sit at 61-67 this season. After this series, the Giants will head home for a series against the Chicago Cubs.

Giants Lose Three In A Row & 8 Of Last 10

Jung Hoo Lee has 120 hits including a team-high 29 doubles along with 10 triples, 7 home runs and 47 RBIs with 10 stolen bases while Heliot Ramos has 129 hits with 22 doubles, 15 home runs and 53 RBIs. Wilmer Flores also 13 home runs and 63 RBIs while Tyler Fitzgerald has 9 stolen bases as well on the year. Matt Chapman also has 79 hits with 16 home runs and 44 RBIs along with 15 doubles and Willy Adames has 104 hits with 18 doubles, 20 home runs and 63 RBIs of his own this season.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to add on to their 4-1 win over the Chicago Cubs from Thursday’s series finale to sit at 80-48 this season. After this series, the Brewers will take on the Arizona Diamondbacks in a series at home.

Brewers Snap Three-Game Losing Skid

Brice Turang has 132 hits with 14 home runs, 64 RBIs and 21 stolen bases while Jackson Chourio has 123 hits with a team-high 29 doubles, 18 stolen bases, 17 home runs and 67 RBIs and Sal Frelick has 124 hits as well as 3 triples, 9 home runs, 49 RBIs and 18 stolen bases so far this season. Christian Yelich also has 15 stolen bases with 26 homers and 87 RBIs while also adding 14 doubles. Yelich also has a team-high 141 strikeouts up to this point in the year. William Contreras has 13 homers and 61 RBIs as well this season. Joey Ortiz has chipped in 93 hits with 17 doubles, 7 home runs and 43 RBIs and Caleb Durbin also has 18 doubles with 7 homers and 42 RBIs.

Why the Milwaukee Brewers will win

• The Brewers have won each of their last 10 games against teams that held a losing record.
• The Giants have lost eight of their last nine games against National League opponents.
• The Brewers have covered the run line each of their last nine games against teams that held a losing record.
• The Giants have failed to cover the run line in eight of their last nine games against National League opponents.

Milwaukee Brewers Player Prop Facts

• Andrew Vaughn has recorded at least one hit in each of his last 16 home appearances against opponents that held a losing record.
• Jackson Chourio has hit a home run in three of the Brewers’ last four night games against NL West opponents that held a losing record.
• Brice Turang has recorded a Double in three of the Brewers’ last four games as favorites against NL opponents.
• Jose Quintana has recorded a win in seven of his last eight appearances against NL opponents that held a losing record.
• Sal Frelick ranks 8th amongst qualified players for Batting Average (.300) this season.

Total Runs Facts

• Seven of the Brewers’ last eight home games after playing the previous day have gone OVER the total runs line.
• Five of the Giants’ last six night games after playing the previous day have gone UNDER the total runs line.

Brewers vs Giants Prediction

I’m on the Brewers here. Is Jose Quintana my favorite option in the Brewers’ rotation? No, but he’s been good enough to be a solid option for Milwaukee, and the Brewers are still finding ways to win and get the job done. The Giants have not been good against lefties as of late, and I think this is just the prime matchup for Milwaukee to succeed once again here. Give me the Brew Crew.