Nationals vs Diamondbacks Prediction 4/4/25 MLB Picks Today

In this article we will formulate a Nationals vs Diamondbacks prediction for this MLB game on Friday, April 4th at Nationals Park in Washington, DC. Let’s take a look at the prediction for this MLB matchup. 

Washington Nationals Betting Preview

The Washington Nationals are 1-5 this season after they were swept by the Blue Jays by scores of 2-5, 3-5, and 2-4. In their last game, Washington cut the deficit to 3-1 in the sixth and 4-2 in the ninth, but fell short in their comeback attempt. The Nationals recorded five hits and one error in the game, and they were led by Abrams, who went 1-4 with one home run and one RBI in the loss. Washington started Gore, who allowed nine hits and three earned runs over 5.0 innings, while Lord and Ribalta combined to allow zero earned runs over the final three innings. 

Prior to that series, the Nationals lost two out of three against the Phillies by scores of 3-7, 6-11, and 5-1. The Washington pitching staff has a 5.02 ERA with a 1.67 WHIP and a .300 on base percentage, while their offense has scored 21 runs with a .213 batting average and a .279 on base percentage this year. Nathaniel Lowe has led Washington with two home runs and six RBIs, while Keibert Ruiz has added two home runs and five RBIs this season. The projected starting pitcher for Washington is Jake Irvin, who is 0-0 with a 3.60 ERA and a 1.80 WHIP over 5.0 innings pitched this year. 

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 4-3 this year after they won two out of three against the Yankees in their last series. Arizona won games one and two by scores of 7-5 and 4-3, but they did lose game three by a score of 9-7. In that game three loss, the Diamondbacks trailed 9-3 in the fourth inning, but they didn’t allow any more runs and added four in the seventh, before falling short in the loss. Arizona recorded eight hits in the game and they were led by Perdomo, who went 1-5 with one home run and four RBIs in the loss. The Diamondbacks started Kelly, who allowed nine hits and nine earned runs over 3.2 innings, while Nelson, Beeks, and Miller combined for 4.1 scoreless innings out of the bullpen. 

Prior to that series, the Diamondbacks split four games with the Cubs by scores of 6-10, 8-1, 3-4, and 10-6. The Arizona pitching staff has a 5.23 ERA with a 1.26 WHIP and a .224 opponent batting average, while the offense has scored 45 runs with a .267 batting average and a .363 on base percentage this season. Eugenio Suarez has led Arizona with five home runs and 11 RBIs, while Geraldo Perdomo has added one home run and 11 RBIs this year. The projected starting pitcher for Arizona is Brandon Pfaadt, who is 0-1 with a 4.50 ERA and a 1.17 WHIP over 6.0 innings pitched this season. 

Why the Diamondbacks will beat the Nationals

• The Nationals have lost each of their last 11 games against NL West opponents that held a winning record.
• The Diamondbacks have won each of their last seven games against NL East opponents that held a losing record.
• The Diamondbacks have covered the run line in each of their last nine night games against the Nationals at Nationals Park following a loss.
• The Nationals have failed to cover the run line in seven of their last eight night games against NL West opponents that held a winning record.
• The Diamondbacks have led after 3 innings in eight of their last nine games against NL East opponents.
• The Diamondbacks have won the first inning in five of their last six road games against National League opponents that held a losing record.
• The Diamondbacks have led after 5 innings in each of their last eight games against the Nationals at Nationals Park.

Total Runs Facts

• Each of the last five games between the Diamondbacks and Nationals at Nationals Park have gone UNDER the total runs line.
• Five of the Diamondbacks’ last six night games against NL East opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last eight night games between the Diamondbacks and Nationals.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Diamondbacks’ last 12 road games against National League opponents.

Washington Nationals Player Prop Facts

• Nathaniel Lowe has hit at least one home run in three of his last four appearances with his team as a home underdog against NL opponents.
• Luis Garcia has scored at least one run in each of his last 12 Friday appearances against teams that held a winning record.
• Keibert Ruiz has recorded at least one hit in each of his last 11 home appearances.
• Amed Rosario has recorded at least one RBI in each of his last five appearances against NL West opponents.
• Amed Rosario has recorded at least one Single in each of his last seven appearances against NL West opponents.

Arizona Diamondbacks Player Prop Facts

• Eugenio Suarez has hit at least one home run in each of the Diamondbacks’ last five games as favorites.
• Josh Naylor has recorded at least one Single in each of his last eight appearances against opponents that held a losing record.
• Corbin Carroll has scored at least one run in each of the Diamondbacks’ last nine night games against NL East opponents that held a losing record.
• Lourdes Gurriel Jr. has recorded at least one hit in each of his last 16 road appearances against NL East opponents.
• Geraldo Perdomo has recorded at least one RBI in seven of the Diamondbacks’ last eight games.
• Brandon Pfaadt has recorded a win in each of his last three appearances with the Diamondbacks as road favorites.
• Randal Grichuk has recorded a Double in four of his last five appearances against opponents that held a losing record.
• Eugenio Suarez ranks T1st in the league in Home Runs (5) this season.

Nationals vs Diamondbacks Prediction 

Arizona comes into this contest after picking up an impressive series win over the Yankees earlier this week and their offense has scored 7+ runs in three of their last four games. Washington is coming off of the wrong end of a sweep in Toronto and they only have one win on the season. Arizona is definitely the better offensive team in this matchup, but they will be facing Jake Irvin, who has the ability to pitch very well when he is on. Arizona is going with Brandon Pfaadt, who also has plenty of talent, but wasn’t great against the Cubs in his first start. I think both pitchers are relatively similar, so I will take the much better offensive team here. Take Arizona to win.