Nationals vs Giants Prediction 5/23/25 MLB Picks Today

The San Francisco Giants and the Washington Nationals meet Friday in MLB action from Nationals Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Nationals vs Giants Prediction.

Starting Pitching Matchup

Landen Roupp will get the start for the Giants here and is 2-3 with a 4.11 ERA and 47 strikeouts this season. This will be Roupp’s first career start against the Nationals. Washington will start MacKenzie Gore here, and Gore is 2-4 with a 3.67 ERA and 84 strikeouts this season. In his career, Gore is 3-1 with a 6.05 ERA and 22 strikeouts against the Giants.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to bounce back from an 8-4 loss at the hands of the Kansas City Royals last time out to fall to 29-21 on the year. After this series, the Giants will head on the road for an interleague series against the Detroit Tigers.

Giants Alternate Wins & Losses In 4 Straight

Jung Hoo Lee has 53 hits, including a team-high 14 doubles along with a pair of triples, 6 home runs, and 31 RBIs with 3 stolen bases, while Heliot Ramos has 55 hits with 11 doubles, 9 home runs, and 26 RBIs. Wilmer Flores also has a team-high 10 home runs and 42 RBIs, while Mike Yastrzemski has 5 home runs with 17 RBIs and 9 doubles, and Matt Chapman and Tyler Fitzgerald each have a team-high 5 stolen bases as well on the year. Matt Chapman also has 38 hits with 9 home runs and 25 RBIs, along with 7 doubles, and Willy Adames has 42 hits with 10 doubles, 5 home runs, and 23 RBIs.

Why the San Francisco Giants will win

• The Giants have won each of their last seven games following a home loss.
• The Nationals have lost each of their last six games after going to extra innings.
• The Nationals have failed to cover the run line in each of their last six games after going to extra innings.
• The Giants have covered the run line in eight of their last nine games against National League opponents.

San Francisco Giants Player Prop Facts

• Mike Yastrzemski has hit a home run in each of the Giants’ last two games as favorites against NL East opponents.
• Willy Adames has recorded a Double in each of the Giants’ last four games against NL opponents.
• Matt Chapman has recorded at least one RBI in four of the Giants’ last five games as favorites against NL East opponents.
• Heliot Ramos has scored at least one run in each of his last eight road appearances against NL East opponents.
• Heliot Ramos has recorded a Single in each of the Giants’ last eight games as favorites.
• Wilmer Flores has recorded at least one hit in each of his last nine appearances against NL opponents.

Washington Nationals Recap

The Washington Nationals come into this game looking to keep the ball rolling after picking up an 8-7 win over the Atlanta Braves last time out to improve to 23-27 on the year. After this series, the Nationals will head on the road for a series against the Seattle Mariners.

Nationals Win 5^th In A Row

Keibert Ruiz has 47 hits with 9 doubles and a pair of home runs with 20 RBIs, while James Wood has 55 hits with 12 doubles and a team-high 12 home runs, along with 33 RBIs and 7 stolen bases while also putting up 57 strikeouts. Nathaniel Lowe has 42 hits with 8 doubles and 34 RBIs, along with 8 home runs and 57 strikeouts. CJ Abrams has 8 home runs and 19 RBIs along with 9 doubles and 9 stolen bases, while Luis Garcia Jr. has 7 doubles and 7 stolen bases of his own this season. Dylan Crews has also logged a team-high 11 stolen bases this season.

Why the Washington Nationals will win

• The Nationals have won each of their last five games as underdogs.
• The Giants have lost four of their last five games as road favorites.
• The underdogs have covered the run line in 13 of the Giants’ last 14 games.
• The Giants have failed to cover the run line in seven of their last eight games as favorites.

Washington Nationals Player Prop Facts

• Keibert Ruiz has recorded a Double in each of the Nationals’ last three games against NL opponents.
• MacKenzie Gore has recorded a win in each of his last three appearances against NL West opponents.
• Keibert Ruiz has recorded at least one RBI in each of the Nationals’ last four games.
• CJ Abrams has scored a run in four of his last five appearances against NL West opponents that held a winning record.
• MacKenzie Gore has recorded seven or more strikeouts in eight of his last nine appearances against NL opponents.
• CJ Abrams has recorded at least one hit in each of the Nationals’ last 14 games against NL opponents that held a winning record.
• Amed Rosario has recorded at least one Single in each of his last seven appearances with the Nationals as underdogs.
• Paul DeJong has hit a home run in each of his last two appearances with his team as a home underdog against the Giants.
• MacKenzie Gore ranks 1st in the league for total Strikeouts (84) this season.

Total Runs Facts

• Each of the Giants’ last seven road games against NL East opponents have gone OVER the total runs line.
• Each of the Nationals’ last four home games against NL West opponents have gone OVER the total runs line.

Nationals vs Giants Prediction

I’m on the Nationals here. The Nationals are playing arguably their best run of baseball so far this season. I think this is definitely a spot where I can get behind them because the Giants, for me, are just a team that I don’t necessarily love on the road and against left-handed pitching. I’m also not the biggest fan of Landen Roupp, and I think the Nationals could get to him here to keep their win streak going. Give me the Nationals in this one.