Orioles vs Blue Jays Prediction 9/22/26 MLB Picks Today

In this article we will formulate an Orioles vs Blue Jays prediction for this MLB game on Tuesday, September 22nd at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 76-81 this year after they won game one by a score of 4-3 last night. Baltimore trailed for most of the game, but they got two runs in the eighth to escape with the win. The Orioles recorded six hits in the game and they were led by Alonso, who went 2-4 with two home runs and three RBIs. Baz allowed five hits and three earned runs over 6.2 innings, while Cano got the win and Garcia picked up the save. Prior to this series, Baltimore lost all three against the Brewers, but did win all three against the Mets before that. 

This season, Baltimore has a 4.11 ERA with a 1.34 WHIP and a .252 opponent batting average, while they have scored 697 runs with a .234 batting average and a .314 on base percentage. Pete Alonso has led the Orioles with 40 home runs and 108 RBIs, while Gunnar Henderson has added 24 home runs and 59 RBIs. The projected starting pitcher for Baltimore is Chris Bassitt, who is 8-5 with a 4.64 ERA and a 1.55 WHIP over 97.0 innings pitched this year. 

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 77-80 this season after they lost game one by a score of 3-4 on Monday. Toronto scored three runs in the first inning, but they went scoreless over the last eight innings for the loss. The Blue Jays recorded six hits in the game and they were led by Lukes, who went 1-3 with one RBI. Yesavage allowed one hit and one earned run over 2.0 innings, while Roger blew the save and took the loss. Prior to this series, Toronto lost two out of three against the Rangers and two out of three against the Tigers. 

This season, Toronto has a 3.92 ERA with a 1.30 WHIP and a .236 opponent batting average, while they have scored 632 runs with a .248 batting average and a .310 on base percentage. Kazuma Okamoto has led the Blue Jays with 33 home runs and 89 RBIs, while Andres Gimenez has added nine home runs and 58 RBIs. The projected starting pitcher for Toronto is Max Scherzer, who is 3-8 with a 6.07 ERA and a 1.36 WHIP over 72.2 innings pitched this season. 

Why the Baltimore Orioles will win

• The Blue Jays have lost each of their last six night games against AL opponents.
• The Orioles have won 10 of their last 11 night games against teams that held a losing record.
• The Blue Jays have failed to cover the run line in each of their last six night games against AL opponents.
• The Orioles have covered the run line in seven of their last eight home games against AL opponents that held a losing record.
• The Orioles have led after 3 innings in four of their last five night games against AL opponents that held a losing record.
• The Orioles have led after 5 innings in four of their last five games as favorites against AL opponents.

Why the Toronto Blue Jays will win

• The Blue Jays have won 10 of their last 11 games as underdogs following a loss.
• The Orioles have lost five of their last six games as favorites against AL East opponents following a home win.
• The Blue Jays have covered the run line in 10 of their last 11 games as underdogs following a loss.
• The Orioles have failed to cover the run line in five of their last six games as favorites.
• The Blue Jays have led after 3 innings in each of their last four road games against AL East opponents that held a losing record.
• The Blue Jays have led after 5 innings in each of their last four road games against AL East opponents that held a losing record.
• The Orioles have lost the first inning in each of their last three home games against AL opponents.

Total Runs Facts

• Nine of the last 10 games between the Blue Jays and Orioles have gone OVER the total runs line.
• Seven of the Blue Jays’ last eight games as underdogs against the Orioles have gone OVER the total runs line.
• There has been at least one run scored in the first inning in each of Max Scherzer’s last eight appearances as a starter.
• There has been at least one run scored in the first inning in each of the Orioles’ last four night games against AL opponents.

Baltimore Orioles Player Prop Facts

• Pete Alonso has hit at least one home run in four of the Orioles’ last five night games.
• Chris Bassitt has recorded four or more strikeouts in 28 of his last 29 home appearances against AL opponents that held a losing record.
• Pete Alonso has recorded at least one hit in each of his last six home appearances against the Blue Jays.
• Chris Bassitt has recorded a win in four of his last five appearances.
• Pete Alonso ranks T4th in the league in Home Runs (40) this season.

Toronto Blue Jays Player Prop Facts

• Kazuma Okamoto has hit a home run in four of the Blue Jays’ last seven night games against opponents that held a losing record.
• Max Scherzer has recorded six or more strikeouts in six of his last seven road appearances against the Orioles.
• Alejandro Kirk has recorded at least one hit in each of his last 14 appearances with the Blue Jays as underdogs.
• Kazuma Okamoto ranks T10th in the league in Home Runs (33) this season.

Matchup/League Facts

• The Orioles rank 28th in the league for strikeouts against this season (1474).
• The Orioles rank 27th in the league for batting average this season (.234).
• The Blue Jays rank 30th in the league for triples this season (8).
• The Blue Jays rank 29th in the league for runs scored this season (632).

Orioles vs Blue Jays Prediction 

Baltimore was able to get the comeback win to start this series on Monday, but they were shutout in the two previous games. The Orioles are 37-42 at home this year, while the Blue Jays are 37-42 on the road. Toronto has also lost three of their last four games and they have scored three runs or fewer in all three of those losses. The Jays are starting Scherzer, who has allowed 1, 6, 3, 0, and 2 earned runs in his last five outings, while Bassitt has allowed 1, 2, 3, 5, and 1 earned run in his last five starts. Take the over here, as I don’t trust either starter.