Orioles vs Guardians Prediction 4/15/25 MLB Picks Today

The Cleveland Guardians and Baltimore Orioles meet on Tuesday in MLB action at Oriole Park at Camden Yards. Here’s an Orioles vs Guardians Prediction. This article will include an Orioles vs Guardians Pick.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 8-7 on the year and play the Pirates, Yankees, and Red Sox next. The Cleveland Guardians are batting .222 on the season and have a .306 OBP and a .373 slugging percentage. The Cleveland Guardians’ pitching staff has a 3.60 ERA and a 1.35 WHIP. Steven Kwan leads the Cleveland Guardians with 19 hits and 8 RBI, while Carlos Santana and Gabriel Arias have combined for 26 hits and 12 RBI.

Logan Allen gets the ball for the Cleveland Guardians, and he is 0-1 with a 3.60 ERA and 5 strikeouts this season. Allen is 1-0 with a 5.40 ERA and 15 strikeouts in his career against the Baltimore Orioles.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 6-9 on the year and play the Reds, Nationals, and Tigers next. The Baltimore Orioles are batting .235 on the season, have a .302 OBP, and a .383 slugging percentage. The Baltimore Orioles pitching staff has a 4.57 ERA and a 1.44 WHIP. Adley Rutschman leads the Baltimore Orioles with 14 hits and 6 RBI, while Tyler O’Neill and Cedric Mullins have combined for 26 hits and 24 RBI.

Charlie Morton gets the ball for the Baltimore Orioles, and he is 0-3 with an 8.78 ERA and 17 strikeouts this season. Morton is 4-2 with a 2.53 ERA and 45 strikeouts in his career against the Cleveland Guardians.

Why the Baltimore Orioles will win

• The home team has won seven of the Guardians’ last eight games.
• The Guardians have lost each of their last four road games against AL East opponents.
• The Guardians have failed to cover the run line in each of their last six games as underdogs against AL East opponents.
• The favorites have covered the run line in each of the Guardians’ last four games.
• The Orioles have led after 3 innings in each of their last five night games against AL Central opponents.
• The Guardians have trailed after 5 innings in each of their last four games as underdogs.

Why the Cleveland Guardians will win

• The Guardians have won each of their last 11 Tuesday games against teams that held a losing record.
• The Orioles have lost each of their last five games as favorites against AL Central opponents.
• The Guardians have covered the run line each of their last six road games against teams that held a losing record.
• The Orioles have failed to cover the run line each of their last six home games against teams that held a winning record.
• The Guardians have won the first inning in each of their last three night games against opponents that held a losing record.
• The Guardians have led after 5 innings in each of their last six road games against American League opponents that held a losing record.
• The Guardians have led after 3 innings in seven of their last eight games against opponents that held a losing record.

Orioles vs Guardians Prediction

The Orioles have been a disappointment up to this point, and Morton isn’t a pitcher I’m excited to get behind. Through 13.1 innings, Morton has allowed 17 hits and 13 runs while walking eight. The Guardians are coming off a strong week, and Allen has allowed just four earned runs in his first 10 innings. We’re getting the pitcher in better form and the team that’s playing better ball overall with the more favorable price. The Orioles are too talented to stay in this funk forever, but the value in this game, in particular, is with the Guardians and the plus money.