
Padres vs Pirates Prediction 5/31/25 MLB Picks Today
Pittsburgh Pirates (21-37) vs. San Diego Padres (32-23)
May 31, 2025 9:40 pm EDT
The Line: San Diego Padres -218 / Pittsburgh Pirates 180; Over/Under: 7.5
(Get latest betting odds)
The Pittsburgh Pirates and San Diego Padres meet Saturday in MLB action at Petco Park. Here’s a Padres vs Pirates Prediction. This article will include a Padres vs Pirates Pick.
Pittsburgh Pirates Betting Preview
The Pittsburgh Pirates are 21-37 on the year and play the Astros, Phillies, and Marlins next. The Pittsburgh Pirates are batting .226 on the season, have a .305 OBP, and a .335 slugging percentage. The Pittsburgh Pirates pitching staff has a 3.98 ERA and a 1.25 WHIP. Byran Reynolds leads the Pittsburgh Pirates with 50 hits and 32 RBI, while Isiah Kiner-Falefa and Ke’Bryan Hayes have combined for 92 hits and 29 RBI.
Bailey Falter gets the ball for the Pittsburgh Pirates, and he is 3-3 with a 3.47 ERA and 40 strikeouts this season. Falter is 0-0 with a 3.38 ERA and 10 strikeouts in his career against the San Diego Padres.
San Diego Padres Betting Preview
The San Diego Padres are 32-23 on the year and play the Giants, Brewers, and Dodgers next. The San Diego Padres are batting .251 on the season, have a .317 OBP, and a .388 slugging percentage. The San Diego Padres pitching staff has a 3.58 ERA and a 1.20 WHIP. Manny Machado leads the San Diego Padres with 64 hits and 25 RBI while Fernando Tatis Jr. and Luis Arraez have combined for 114 hits and 48 RBI.
Dylan Cease gets the ball for the San Diego Padres, and he is 1-3 with a 4.58 ERA and 72 strikeouts this season. Cease is 1-0 with a 2.87 ERA and 14 strikeouts in his career against the Pittsburgh Pirates.
Why the San Diego Padres will win
- The Padres have won each of their last 12 night games against National League opponents that held a losing record.
- The Pirates have lost each of their last nine games against the Padres following a loss.
- The Padres have covered the run line in each of their last seven night games against NL Central opponents following a home win.
- The Pirates have failed to cover the run line in each of their last seven Saturday road games against National League opponents.
- The Padres have led after 3 innings in six of their last eight games as favorites against NL Central opponents.
- The Pirates have trailed after 5 innings in each of their last five road night games.
Why the Pittsburgh Pirates will win
- The Padres have lost six of their last nine games as favorites.
- The Pirates have won six of their last nine games as underdogs against the Padres following a road loss.
- The Padres have failed to cover the run line in eight of their last nine games as favorites.
- The Pirates have covered the run line in seven of their last eight night games against the Padres following a road loss.
- The Padres have lost the first inning in three of their last four night games against National League opponents that held a losing record.
San Diego Padres Player Prop Facts
- Luis Arraez has recorded at least one Double in four of the Padres’ last five games as favorites against NL Central opponents.
- Fernando Tatis Jr. has hit a home run in three of the Padres’ last four Saturday night games against opponents that held a losing record.
- Dylan Cease has recorded eight or more strikeouts in three of his last four appearances.
- Luis Arraez has scored at least one run in each of the Padres’ last eight games as favorites against NL Central opponents.
- Luis Arraez has recorded at least one Single in 16 of his last 17 home appearances after playing the previous day.
- Manny Machado has recorded at least one hit in each of the Padres’ last 19 games against NL opponents.
- Jason Heyward has recorded at least one RBI in each of his last four appearances in night games against NL teams that held a losing record.
Pittsburgh Pirates Player Prop Facts
- Adam Frazier has scored at least one run in each of his last six Saturday appearances at Petco Park.
- Bryan Reynolds has recorded at least one RBI in six of his last seven appearances after playing the previous day.
- Andrew McCutchen has recorded a Single in nine of his last 10 appearances in night games against NL West teams that held a winning record.
- Tommy Pham has recorded at least one hit in each of his last 11 Saturday night appearances against teams that held a winning record.
- Tommy Pham has hit a home run in seven of his last 16 road appearances against the Padres.
- Oneil Cruz ranks T4th in the league in Steals (18) this season.
Padres vs Pirates Prediction
The Pirates are one of those teams I’ve bet against a lot this season, and there are not many spots where they have value. The Padres should be comfortable favorites at home. With that said, we’re getting a big plus money price with Falter on the mound. In his last 29.1 innings, Falter has allowed 15 hits and three earned runs while striking out 18. Falter has allowed two earned runs in his last 22.1 innings. There are not many spots where you can find value with the Pirates. Given Falter’s month of May, there’s reason to consider the big plus money. Give me the Pirates.