Padres vs Rays Prediction 4/26/25 MLB Picks Today

In this article, we will formulate a Padres vs Rays prediction for this MLB game on Saturday, April 26th at Petco Park in San Diego, California. Let’s take a look at the prediction for this MLB matchup. 

San Diego Padres Betting Preview

The San Diego Padres are 17-9 this year after they lost game one in this series by a score of 1-0 on Friday night. San Diego allowed a run in the third inning, and their pitching was great all night, but the offense really let them down. The Padres recorded five hits and they committed one error in the game, while they were led by Tatis Jr., who had two hits in the loss. San Diego started King, who allowed four hits and one unearned run over 5.0 innings for the loss, while four pitchers held TB scoreless in the final four innings. 

Prior to this series, the Padres lost two out of three against the Tigers and two out of three against the Astros. San Diego has lost five of their last seven games, and they are currently tied for first in the NL West standings. The San Diego pitching staff has a 2.80 ERA with a 1.11 WHIP and a .207 opponent batting average, while their offense has scored 103 runs with a .260 batting average and a .329 on-base percentage this season. Fernando Tatis has led San Diego with eight home runs and 17 RBIs, while Gavin Sheets has added three home runs and 12 RBIs this year. The projected starting pitcher for San Diego is Dylan Cease, who is 1-1 with a 6.04 ERA and a 1.50 WHIP over 25.1 innings pitched this year. 

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 12-14 this season after they escaped with the 1-0 win on Friday night. Tampa Bay was able to take advantage of a San Diego error for their lone run in the game, which was enough to get the win. The Rays recorded six hits in the game, and they were led by Diaz, who had their lone RBI in the win. TB started Baz, who allowed four hits over 7.0 innings for the win, while Cleavinger picked up the save. 

Prior to this series, the Rays won two out of three against the Diamondbacks, but did lose three out of four against the Yankees before that. Tampa Bay has won three games in a row, and they are currently fourth in the AL East standings. The Tampa Bay pitching staff has a 3.61 ERA with a 1.15 WHIP and a .229 opponent batting average, while the offense has scored 110 runs with a .252 batting average and a .317 on-base percentage this season. Junior Caminero has led Tampa Bay with five home runs and 12 RBIs, while Jonathan Aranda has added four home runs and 13 RBIs for the Rays this year. The projected starting pitcher for Tampa Bay is Ryan Pepiot, who is 1-3 with a 4.82 ERA and a 1.50 WHIP over 28.0 innings pitched this season. 

Why the Padres will beat the Rays

• The Padres have won each of their last eight games as home favorites after playing the previous day.
• The Padres have covered the run line in each of their last 10 home games after playing the previous day.
• The Rays have trailed after 5 innings in six of their last seven games.
• The Padres have led after 3 innings in four of their last five night games against AL East opponents that held a losing record.

Total Runs Facts

• Six of the Padres’ last seven games after playing the previous day have gone UNDER the total runs line.
• Twenty-four of the Rays’ last 32 night games against NL West opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Padres’ last nine home games against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Rays’ last four games at Petco Park.

San Diego Padres Player Prop Facts

• Gavin Sheets has hit a home run in three of his last four appearances with his team as a home favorite against AL East opponents.
• Fernando Tatis Jr. has recorded a Double in three of the Padres’ last four home games against the Rays.
• Dylan Cease has recorded a win in four of his last five appearances with his team as a home favorite against AL opponents .
• Dylan Cease has recorded seven or more strikeouts in eight of his last nine home appearances against opponents that held a losing record.
• Manny Machado has recorded at least one Single in each of his last 12 appearances against AL East opponents that held a losing record.
• Manny Machado has recorded at least one hit in each of his last 12 appearances against AL East opponents that held a losing record.
• Jake Cronenworth has scored at least one run in five of his last six home appearances.
• Jackson Merrill has recorded at least one RBI in each of his last four appearances in night games against AL teams that held a losing record.

Tampa Bay Rays Player Prop Facts

• Danny Jansen has scored a run in six of his last seven appearances with his team as an underdog against NL West opponents.
• Yandy Diaz has recorded at least one RBI in five of the Rays’ last six night games against NL West opponents that held a winning record.
• Yandy Diaz has recorded at least one Single in 10 of his last 11 appearances against NL opponents that held a winning record.
• Ha-Seong Kim has hit a home run in three of his last seven road appearances against NL West opponents.
• Ha-Seong Kim has recorded at least one hit in each of his last six road appearances.

Padres vs Rays Prediction 

Tampa Bay comes into this contest looking to get their fourth straight win, but they are just 3-4 on the road this year. San Diego has one of the best records in the MLB, but they have been shut out in back-to-back games and have scored just two runs in their last three. The Padres are 12-2 at home this year, and they are starting Cease, who has some ugly numbers, but has pitched well in back-to-back starts. Tampa Bay is going with Pepiot, who has been below average to start the season. The San Diego offense is not in a good spot, but I have to roll with them in this game. Take the Padres here.