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Pirates vs Brewers Prediction 4/26/26 MLB Picks Today

Pittsburgh Pirates (16-11) vs. Milwaukee Brewers (13-13)
April 26, 2026 2:10 pm EDT
The Line: Milwaukee Brewers -131 / Pittsburgh Pirates 109; Over/Under: 7.5
(Get latest betting odds)

In this article, we will formulate a Pirates vs Brewers Prediction for this MLB matchup on Sunday, April 26th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Milwaukee Brewers Preview

The Milwaukee Brewers have a 13-13 record this season and are sitting in the fifth place of the NL Central. They have a 7-7 home record and are coming off a 3-6 home loss against the Pirates. Their previous three games were a 0-6 home loss against the Pirates, and a 4-5 and a 2-5 road loss against the Tigers.

The Brewers have a .231 batting average this season, .330 OBP and .349 Slugging percentage. Milwaukee’s pitching staff has a 3.97 ERA and 1.32 WHIP. Brice Turang is the team’s best hitter with a .270 batting average. Garrett Mitchell leads the team in RBI with 19, and Gary Sanchez adds a team‑high 5 home runs.

Kyle Harrison (L) is the projected starting pitcher for the Brewers, and he has a 1-1 record, 3.06 ERA and 1.30 WHIP.

Pittsburgh Pirates Preview

The Pittsburgh Pirates have a 16-11 record this season and are sitting in the third place of the NL Central. They have a 8-6 away record and are coming off a 6-3 road win against the Brewers. Their previous three games were a 6-0 road win against the Brewers, and a 1-6 road loss and an 8-4 road win against the Rangers.

The Pirates have a .246 batting average this season, .330 OBP and .380 Slugging percentage. Pittsburgh’s pitching staff has a 3.30 ERA and 1.24 WHIP. Ryan O’Hearn is the team’s best hitter with a .330 batting average. Oneil Cruz leads the team in RBI with 24, also adding a team‑high 8 home runs.

Carmen Mlodzinski (R) is the projected starting pitcher for the Pirates, and he has a 1-1 record, 3.28 ERA and 1.42 WHIP.

Pittsburgh Pirates @ Milwaukee Brewers Betting Trends: April 26, 2026

 

  • Probable Starting Pitcher: Kyle Harrison      Record this season: 1-1      ERA: 3.06
  • Home Record: 0-1
  • Last 5 against Pirates: 0-0

Why the Milwaukee Brewers will win

  • The Brewers have won each of their last 11 day games against NL Central opponents following a home loss.
  • The Pirates have lost each of their last six games following an extra innings win.
  • The Brewers have covered the run line in seven of their last eight games as favorites against the Pirates.
  • The Pirates have failed to cover the run line in five of their last six games following a win.
  • The Brewers have led after 5 innings in each of their last four day games against the Pirates.
  • The Brewers have led after 3 innings in each of their last four day games against the Pirates.

 

  • Probable Starting Pitcher: Carmen Mlodzinski      Record this season: 1-1      ERA: 3.28
  • Road Record: 0-1
  • Last 5 against Brewers: 1-1

Why the Pittsburgh Pirates will win

  • The Brewers have lost each of their last eight games against National League opponents following a loss.
  • The road team has won each of the last five games between the Pirates and Brewers.
  • The Pirates have covered the run line in each of their last 13 day games after going to extra innings.
  • The Brewers have failed to cover the run line in each of their last eight games against National League opponents following a loss.
  • The Brewers have trailed after 5 innings in three of their last four games.
  • The Brewers have lost the first inning in each of their last three day games against opponents that held a winning record.
  • The Brewers have trailed after 3 innings in each of their last four day games.

Total Runs Facts

  • Each of the Brewers’ last seven games after going to extra innings have gone UNDER the total runs line.
  • Each of the Pirates’ last six day games after playing the previous day have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Pirates’ last 12 day games at American Family Field.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Brewers’ last five games as favorites.

Milwaukee Brewers Player Prop Facts

  • Andrew Vaughn has hit a home run in each of his last two home appearances against NL Central opponents.
  • Christian Yelich has recorded at least one hit in each of his last 13 appearances with the Brewers as favorites against the Pirates.
  • Brice Turang ranks T8th in the league in Steals (7) this season.

Pittsburgh Pirates Player Prop Facts

  • Marcell Ozuna has hit a home run in three of his last five appearances with his team as a road underdog against the Brewers.
  • Bryan Reynolds has recorded at least one hit in each of the Pirates’ last nine games as road underdogs against the Brewers.
  • Oneil Cruz ranks T3rd in the league in Steals (10) this season.

Matchup/League Facts

  • The Brewers rank 1st in the league for steals this season (35).
  • The Brewers rank 28th in the league for hits this season (193).
  • The Pirates rank 3rd in the league for ERA this season (3.32).
  • The Pirates rank 3rd in the league for home runs allowed this season (19).

Pirates vs Brewers Prediction

The Brewers are 8-2 in their last 10 meetings against the Pirates and are 5-2 in their last 7 meetings in Milwaukee.

In this Pirates vs Brewers Prediction, the Brewers are coming as -130 home favorites. The Brewers have lost both games in this series by a combined 12-3 score and have lost four straight. They are putting Kyle Harrison on the mound, who has been good this season, having two earned runs or less in each of his last four starts and has been better at home. On the flip side, Mlodzinski was torched in his last start and has been struggling on the road. Milwaukee also has a slightly better offense and has been better against righties, so I expect them to take care of business at home.

Nikos Lagouretos's Free Pick: Milwaukee Brewers ML

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