Pirates vs Brewers Prediction 9/16/26 MLB Picks Today

In this article we will formulate a Pirates vs Brewers prediction for this MLB game on Wednesday, September 16th at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 75-76 this season after they lost game one by a score of 1-5 on Tuesday. Pittsburgh never really had a chance in the loss, but they scored in the eighth to avoid the shutout. The Pirates recorded 10 hits in the game and they were led by Lowe, who went 1-5 with one home run and one RBI. Bachar allowed one earned run over 2.0 innings for the loss, while Soto allowed four earned runs in relief. Prior to this series, Pittsburgh lost two out of three against the Cubs, but did sweep the White Sox in three games before that. 

This season, Pittsburgh has a 4.18 ERA with a 1.30 WHIP and a .237 opponent batting average, while they have scored 719 runs with a .253 batting average and a .330 on base percentage. Brandon Lowe has led the Pirates with 30 home runs and 86 RBIs, while Ryan O’Hearn has added 18 home runs and 72 RBIs. The projected starting pitcher for Pittsburgh is Jared Jones, who is 4-6 with a 4.10 ERA and a 1.17 WHIP over 85.2 innings pitched this season. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 94-57 this year after they won game one by a score of 5-1 on Tuesday. Milwaukee took the lead in the second inning and never looked back for the win. The Brewers recorded eight hits in the game and they were led by Ortiz, who went 3-4 with two RBIs. Misiorowski allowed five hits and zero earned runs over 5.0 innings for the win, while Hall allowed one earned run in relief. Prior to this series, Milwaukee won two out of three against the Reds and all three against the Cubs. 

This season, Milwaukee has a 3.56 ERA with a 1.19 WHIP and a .223 opponent batting average, while they have scored 783 runs with a .259 batting average and a .342 on base percentage. Jake Bauers has led the Brewers with 26 home runs and 83 RBIs, while Brice Turang has added 19 home runs and 92 RBIs. The projected starting pitcher for Milwaukee is Logan Henderson, who is 10-3 with a 2.34 ERA and a 0.78 WHIP over 88.1 innings pitched this year. 

Why the Pittsburgh Pirates will win

• The Brewers have lost seven of their last eight night games against the Pirates following a road win.
• The Pirates have won each of their last five home games following a loss.
• The Pirates have covered the run line in each of their last nine Wednesday night games as home underdogs against NL opponents.
• The Brewers have failed to cover the run line in seven of their last eight games as road favorites against NL Central opponents following a win.
• The Pirates have led after 5 innings in three of their last four night games.

Why the Milwaukee Brewers will win

• The Brewers have won seven of their last eight night games against teams that held a losing record.
• The Pirates have lost seven of their last eight night games against NL Central opponents that held a winning record.
• The Brewers have covered the run line in each of their last nine games against the Pirates following a win.
• The Pirates have failed to cover the run line each of their last six home games against NL opponents that held a winning record.
• The Brewers have won the first inning in three of their last four games at PNC Park against opponents that held a losing record.
• The Brewers have led after 3 innings in seven of their last eight night games against opponents that held a losing record.
• The Pirates have trailed after 5 innings in each of their last seven games against NL Central opponents that held a winning record.

Total Runs Facts

• Each of the Brewers’ last seven games as favorites against the Pirates have gone UNDER the total runs line.
• Each of the Pirates’ last six night games against NL Central opponents have gone UNDER the total runs line.
• There has been no run scored during the first inning in each of Logan Henderson’s last eight road appearances as a starter.
• There has been no run scored during the first inning in each of the last seven night games between the Brewers and Pirates.

Pittsburgh Pirates Player Prop Facts

• Brandon Lowe has hit a home run in each of the Pirates’ last two games against the Brewers.
• Jared Jones has recorded six or more strikeouts in each of his last four appearances in night games.
• Ryan O’Hearn has recorded at least one hit in each of his last 13 appearances in night games against NL Central teams that held a winning record.
• Nick Gonzales ranks 4th amongst qualified players for Batting Average (.307) this season.

Milwaukee Brewers Player Prop Facts

• William Contreras has hit a home run in four of his last five appearances against opponents that held a losing record.
• Logan Henderson has recorded seven or more strikeouts in each of his last five appearances against opponents that held a losing record.
• Logan Henderson has recorded a win in each of his last four appearances against opponents that held a losing record.
• Andrew Vaughn has recorded at least one hit in each of his last nine appearances in night games against NL teams that held a losing record.
• Jake Bauers ranks 3rd amongst qualified players for On Base Percentage (.393) this season.

Matchup/League Facts

• The Pirates rank T2nd in the league for hits this season (1312).
• The Pirates rank 2nd in the league for home runs allowed this season (145).
• The Brewers rank 1st in the league for hits this season (1331).
• The Brewers rank 1st in the league for on-base percentage this season (.342).

Pirates vs Brewers Prediction 

Milwaukee comes into this matchup after winning four of their last five games and they have scored 46 runs in those four wins. The Brewers are 42-31 on the road this year, while the Pirates are 38-35 at home. Pittsburgh has lost three of their last four games and they have scored three or fewer in four of their last five. The Pirates are starting Jones, who has allowed two earned runs or fewer in four of his last five outings, while Henderson has allowed two earned runs or fewer in five straight. Take the under here.