Pirates vs Brewers Prediction 9/7/25 MLB Picks Today

The Milwaukee Brewers and Pittsburgh Pirates meet Sunday in MLB action at PNC Park. Here’s a Pirates vs Brewers Prediction. This article will include a Pirates vs Brewers Pick.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 88-55 on the year and play the Rangers, Cardinals, and Angels next. The Milwaukee Brewers are batting .259 on the season, have a .332 OBP, and a .408 slugging percentage. The Milwaukee Brewers pitching staff has a 3.60 ERA and a 1.23 WHIP. Brice Turang leads the Milwaukee Brewers with 150 hits and 71 RBI, while Sal Frelick and William Contreras have combined for 277 hits and 123 RBI.

Jacob Misiorowski gets the ball for the Milwaukee Brewers, and he is 4-2 with a 4.50 ERA and 69 strikeouts this season. This will be Misiorowski’s second career game against the Pittsburgh Pirates.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 64-79 on the year and play the Orioles, Nationals, and Cubs next. The Pittsburgh Pirates are batting .234 on the season, have a .307 OBP, and a .352 slugging percentage. The Pittsburgh Pirates pitching staff has a 3.87 ERA and a 1.22 WHIP. Bryan Reynolds leads the Pittsburgh Pirates with 129 hits and 70 RBI while Andrew McCutchen and Tommy Pham have combined for 194 hits and 101 RBI.

Bubba Chandler gets the ball for the Pittsburgh Pirates, and he is 2-0 with a 2.25 ERA and 9 strikeouts this season. This will be Chandler’s first career game against the Milwaukee Brewers.

Milwaukee Brewers @ Pittsburgh Pirates Betting Trends: September 7, 2025

• Probable Starting Pitcher: Bubba Chandler      Record this season: 2-0      ERA: 2.25
• Home Record: 1-0
• Last 5 against Brewers: –

Why the Pittsburgh Pirates will win

• The underdogs have won eight of the Brewers’ last 10 games.
• The Brewers have lost seven of their last nine games as favorites against the Pirates following a road win.
• The Pirates have covered the run line in seven of their last eight games following a loss.
• The Brewers have failed to cover the run line in seven of their last eight games as favorites following a win.
• The Pirates have led after 3 innings in five of their last six games as home underdogs.
• The Pirates have led after 5 innings in seven of their last eight day games at PNC Park against National League opponents.

• Probable Starting Pitcher: Jacob Misiorowski      Record this season: 4-2      ERA: 4.50
• Road Record: 1-2
• Last 5 against Pirates: 1-0

Why the Milwaukee Brewers will win

• The Brewers have won each of their last nine road games against teams that held a losing record.
• The Pirates have lost nine of their last 10 games against NL Central opponents that held a winning record.
• The Brewers have covered the run line each of their last nine road games against teams that held a losing record.
• The Pirates have failed to cover the run line in each of their last six games against the Brewers following a loss.
• The Brewers have led after 5 innings in eight of their last nine road games against opponents that held a losing record.
• The Brewers have led after 3 innings in each of their last four day games against NL Central opponents that held a losing record.

Total Runs Facts

• Each of the Pirates’ last four games against NL Central opponents have gone UNDER the total runs line.
• Eight of the Brewers’ last 10 day games as favorites have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Pirates’ last eight day games against NL Central opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Brewers’ last five day games at PNC Park.

Pittsburgh Pirates Player Prop Facts

• Andrew McCutchen has hit a home run in six of his last 19 appearances with the Pirates as home underdogs against the Brewers.
• Tommy Pham has recorded at least one hit in 17 of his last 18 appearances in day games.
• Jack Suwinski has recorded a Double in three of his last four appearances with the Pirates as home underdogs against the Brewers.
• Oneil Cruz ranks T3rd in the league in Steals (37) this season.

Milwaukee Brewers Player Prop Facts

• Christian Yelich has recorded at least one hit in each of his last 18 appearances against NL Central opponents that held a losing record.
• Christian Yelich has hit a home run in two of his last three appearances against the Pirates.
• Sal Frelick ranks 8th amongst qualified players for Batting Average (.299) this season.

Matchup/League Facts

• The Pirates rank 30th in the league for runs scored this season (520).
• The Pirates rank 30th in the league for home runs this season (102).
• The Brewers rank 2nd in the league for runs scored this season (726).
• The Brewers rank 2nd in the league for hits this season (1258).

Pirates vs Brewers Prediction

Misiorowski has been shaky as of late, allowing 15 hits and 14 runs in his last 14.2 innings. Misiorowski also has a 7.23 ERA in 18.2 innings on the road. With that said, the Brewers are comfortably the better team and continue to fatten the pockets of MLB bettors. Chandler has just 12 MLB innings under his belt, so the jury is still out on the 22-year-old. I’m going to keep backing the teams that keep making us coin. The Brewers are one of those teams. Misiorowski should also right the ship sooner than later. Give me the Brewers.