Pirates vs Diamondbacks Prediction 7-27-25 MLB Picks

The Arizona Diamondbacks and the Pittsburgh Pirates meet Sunday in MLB action from PNC Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Pirates vs Diamondbacks Prediction.

Starting Pitching Matchup

The Arizona Diamondbacks will send out Zac Gallen for the start here, and Gallen is 7-11 with a 5.58 ERA and 116 strikeouts this season. In his last five starts against the Pirates, Gallen is 3-2 with a 4.40 ERA and 24 strikeouts. Paul Skenes will get the start for the Pirates here, and Skenes is 5-8 with a 1.91 ERA and 137 strikeouts this season. In his career, Skenes is 1-0 with a 1.50 ERA and 11 strikeouts against Arizona.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to rebound from their 2-0 loss at the hands of the Pirates on Saturday to sit at 51-54 on the year. After this series, the Diamondbacks will head to Detroit to take on the Tigers.

Diamondbacks Drop 4 Of Their Last 5

Corbin Carroll has 88 hits with 21 home runs, 50 RBIs, 13 triples, and 18 doubles this season. Eugenio Suarez has also added 36 home runs and 87 RBIs, while Geraldo Perdomo has 72 RBIs. Suarez has the unfortunate distinction of leading the Diamondbacks with 111 strikeouts so far this season. Carroll also has 13 stolen bases, and Perdomo has a team-high 15 stolen bases as well this season. Ketel Marte’s added 20 home runs and 41 RBIs as well on the year, and Lourdes Gurriel has 93 hits with 20 doubles, 12 home runs, and 48 RBIs.

Why the Arizona Diamondbacks will win

• The Diamondbacks have won each of their last five games as underdogs against the Pirates following a road loss.
• The Pirates have lost each of their last three games as favorites against the Diamondbacks following a home win.
• The Diamondbacks have covered the run line in each of their last eight games as road underdogs against National League opponents.
• The Pirates have failed to cover the run line in 11 of their last 13 games as favorites following a win.

Arizona Diamondbacks Player Prop Facts

• Eugenio Suarez has hit a home run in each of the Diamondbacks’ last two day games against NL Central opponents that held a losing record.
• Zac Gallen has recorded six or more strikeouts in three of his last four appearances against NL opponents.
• Zac Gallen has recorded a win in four of his last five road appearances against NL opponents that held a losing record.
• Randal Grichuk has recorded a Double in three of his last four appearances against the Pirates after playing the previous day.
• Ildemaro Vargas has recorded at least one hit in each of his last nine appearances with his team as an underdog against NL Central opponents.
• Eugenio Suarez ranks T4th in the league in Home Runs (36) this season.

Pittsburgh Pirates Recap

The Pittsburgh Pirates come into this game looking to add on to their win over Arizona on Saturday to sit at 43-62 this season. After this series, the Pirates will head on the road for a series against the Giants.

Pirates Win 4 Of Their Last 5

Bryan Reynolds has 90 hits with 21 doubles, 10 home runs, and 50 RBIs while also posting 114 strikeouts so far this season. Oneil Cruz has posted a team-high 16 home runs and 40 RBIs with 34 stolen bases, while Isiah Kiner-Falefa has 80 hits with 12 doubles and 12 stolen bases. Cruz also has a team-high 124 strikeouts this season. Tommy Pham has 10 doubles and Andrew McCutchen has 82 hits with 15 doubles, and KeBryan Hayes has 85 hits with 34 RBIs and 10 stolen bases.

Why the Pittsburgh Pirates will win

• The Pirates have won eight of their last nine home games against National League opponents.
• The Diamondbacks have lost seven of their last eight road games against NL Central opponents.
• The Diamondbacks have failed to cover the run line each of their last seven games against NL Central opponents that held a losing record.
• The Pirates have covered the run line each of their last six day games against National League opponents that held a losing record.

Pittsburgh Pirates Player Prop Facts

• Oneil Cruz has hit a home run in two of the Pirates’ last three games against the Diamondbacks.
• Tommy Pham has recorded at least one hit in each of his last 10 appearances after playing the previous day.
• Jack Suwinski has recorded at least one Double in three of his last four home appearances against the Diamondbacks.
• Oneil Cruz ranks 1st in the league in Steals (34) this season.

Total Runs Facts

• Seven of the Pirates’ last eight day games as favorites have gone UNDER the total runs line.
• Each of the Diamondbacks’ last four games have gone UNDER the total runs line.

Pirates vs Diamondbacks Prediction

I’m on the Pirates in this one. I get the case to be made for the Diamondbacks because it’s no accident that Paul Skenes has a sub-2.00 ERA and a losing record on the year. Far more often than not, his offense has had issues getting him run support. However, there are times when 2–3 runs is enough for the Pirates’ ace, as he’s been that strong, and I think this is another one of those instances as the Diamondbacks look like a team that’s playing out the string. I’ll roll with Pittsburgh here.