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Reds vs Blue Jays Prediction 9/3/25 MLB Picks Today

Toronto Blue Jays (80-59) vs. Cincinnati Reds (70-69)
September 3, 2025 6:40 pm EDT
The Line: Cincinnati Reds 137 / Toronto Blue Jays -167; Over/Under: 8.5
(Get latest betting odds)

In this article we will formulate a Reds vs Blue Jays prediction for this MLB game on Wednesday, September 3rd at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 70-69 this year after they split the first two games in this series by scores of 5-4 and 9-12. In their game two loss, Cincinnati trailed 8-1 in the second inning, but made a pretty good attempt at a comeback, before taking the loss. The Reds recorded 15 hits in the game and they were led by Hays, who went 2-5 with one home run and four RBIs in the loss. Cincinnati started Barlow, who allowed two hits and four earned runs over 1.0 inning for the loss, while Suter allowed six earned runs in relief. 

Prior to this series, the Reds lost two out of three against the Cardinals and all three against the Dodgers. Cincinnati has lost six of their last eight games and they are currently third in the NL Central standings. The Cincinnati pitching staff has a 3.90 ERA with a 1.24 WHIP and a .235 opponent batting average, while their offense has scored 625 runs with a .248 batting average and a .318 on base percentage this season. Elly De La Cruz has led Cincinnati with 19 home runs and 78 RBIs, while Spencer Steer has added 17 home runs and 63 RBIs this year. The projected starting pitcher for Cincinnati is Zack Littell, who is 9-8 with a 3.63 ERA and a 1.12 WHIP over 161.0 innings pitched this year. 

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 80-59 this season after they won game two by a score of 12-9 on Tuesday night. Toronto nearly blew an 8-1 lead early in the game, but they were able to overcome some poor pitching for the victory. The Blue Jays recorded 12 hits and they committed one error in the game, while they were led by Springer, Bichette, and Kirk, who all had three RBIs in the win. Toronto started Berrios, who allowed five hits and two earned runs over 2.0 innings, while Varland picked up the win and Hoffman got the save. 

Prior to this series, the Blue Jays lost two out of three against the Brewers, but did win two out of three against the Twins before that. Toronto has lost three of their last five games and they are currently first in the AL East standings. The Toronto pitching staff has a 4.26 ERA with a 1.27 WHIP and a .242 opponent batting average, while their offense has scored 691 runs with a .268 batting average and a .337 on base percentage this season. Vladimir Guerrero Jr. has led Toronto with 21 home runs and 75 RBIs, while George Springer has added 26 home runs and 71 RBIs this year. The projected starting pitcher for Toronto is Shane Bieber, who is 1-1 with a 2.38 ERA and a 0.62 WHIP over 11.1 innings pitched this season. 

Why the Blue Jays will beat the Reds

  • The Reds have lost each of their last seven night games after playing the previous day.
  • The Blue Jays have won four of their last five night games after playing the previous day.
  • The Blue Jays have covered the run line each of their last seven road games against NL Central opponents that held a winning record.
  • The Reds have failed to cover the run line in each of their last seven home games against AL East opponents following a home loss.
  • The Blue Jays have won the first inning in each of their last four games as favorites against the Reds.
  • The Reds have trailed after 5 innings in each of their last eight night games.
  • The Reds have trailed after 3 innings in each of their last five games as underdogs against AL East opponents.

Total Runs Facts

  • Each of the last six games between the Blue Jays and Reds have gone OVER the total runs line.
  • Nine of the Blue Jays’ last 10 games have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last four night games between the Blue Jays and Reds.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Blue Jays’ last seven night games.

Cincinnati Reds Player Prop Facts

  • Elly De La Cruz has recorded at least one hit in each of the Reds’ last 10 home games.
  • Austin Hays has hit a home run in two of the Reds’ last three games.
  • Elly De La Cruz ranks 8th in the league in Steals (32) this season.

Toronto Blue Jays Player Prop Facts

  • Alejandro Kirk has recorded a Double in three of his last four appearances with the Blue Jays as favorites against NL opponents.
  • Bo Bichette has recorded at least one hit in each of his last 14 appearances with the Blue Jays as road favorites against NL Central opponents.
  • Shane Bieber has recorded six or more strikeouts in seven of his last eight appearances with his team as a favorite.
  • Daulton Varsho has hit a home run in four of the Blue Jays’ last five road games.
  • Shane Bieber has recorded a win in each of his last five appearances with his team as a road favorite against NL Central opponents.

Matchup/League Facts

  • The Reds rank 6th in the league for opponent batting average this season (.235).
  • The Reds rank 24th in the league for home runs this season (138).
  • The Blue Jays rank 1st in the league for hits this season (1273).
  • The Blue Jays rank 1st in the league for batting average this season (.268).

Reds vs Blue Jays Prediction 

Both of these teams have struggled over the last week or so, which makes this game very important for each side. The Reds are 38-32 at home this season, while the Blue Jays are 35-35 on the road. Toronto continues to hold off the Yankees and Red Sox in the East, as they are currently up 2.5 games. The Jays are starting Bieber, who has allowed three earned runs and seven hits over 11.1 innings in two starts. The Reds are turning to Littell, who has allowed 3+ earned runs in three of his last four outings. Take the Blue Jays to get the win here. 

David Racey's Free Pick: Blue Jays ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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