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Reds vs Cardinals Prediction 8/18/26 MLB Picks Today

St. Louis Cardinals (64-62) vs. Cincinnati Reds (60-65)
August 18, 2026 6:40 pm EDT
The Line: Cincinnati Reds 108 / St. Louis Cardinals -116; Over/Under: 8.5
(Get latest betting odds)

The St. Louis Cardinals and Cincinnati Reds meet Tuesday in MLB action at Great American Ball Park. Here’s a Reds vs Cardinals Prediction. This article will include a Reds vs Cardinals Pick.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 64-62 on the year and play the Phillies and Orioles next. The St. Louis Cardinals are batting .240 on the season, with a .316 OBP and a .382 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.04 ERA and a 1.34 WHIP. Alec Burleson leads the St. Louis Cardinals with 135 hits and 90 RBI, while Jordan Walker and Ivan Herrera have combined for 247 hits and 140 RBI.

Kyle Leahy gets the ball for the St. Louis Cardinals, and he is 9-4 with a 3.38 ERA and 105 strikeouts this season. Leahy is 0-0 with a 6.12 ERA and 25 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 60-65 on the year and play the Diamondbacks and Giants next. The Cincinnati Reds are batting 226 on the season, have a .306 OBP, and have a .393 slugging percentage. The Cincinnati Reds’ pitching staff has a 4.51 ERA and a 1.40 WHIP. Sal Stewart leads the Cincinnati Reds with 121 hits and 91 RBI, while Elly De La Cruz and Spencer Steer have combined for 188 hits and 96 RBI.

Andrew Abbott gets the ball for the Cincinnati Reds, and he is 6-7 with a 4.13 ERA and 102 strikeouts this season. Abbott is 4-4 with a 3.83 ERA and 42 strikeouts in his career against the St. Louis Cardinals.

Why the Cincinnati Reds will win

  • The Cardinals have lost 11 of their last 12 games as road favorites against NL Central opponents.
  • The Reds have won five of their last six games as home underdogs against the Cardinals.
  • The Cardinals have failed to cover the run line in each of their last 15 games as road favorites against NL Central opponents.
  • The Reds have covered the run line in each of their last nine games as home underdogs against the Cardinals.
  • The Cardinals have trailed after 5 innings in nine of their last 12 games as road favorites against NL Central opponents.
  • The Cardinals have lost the first inning in three of their last four night games at Great American Ball Park.
  • The Cardinals have trailed after 3 innings in four of their last five games at Great American Ball Park against opponents that held a losing record.

Why the St. Louis Cardinals will win

  • The Reds have lost seven of their last eight games against National League opponents following a home win.
  • The Cardinals have won each of their last five games following a loss.
  • The Reds have failed to cover the run line in each of their last eight games following a win.
  • The Cardinals have covered the run line in each of their last seven games against National League opponents following a road loss.
  • The Cardinals have led after 5 innings in seven of their last eight night games against National League opponents that held a losing record.
  • The Cardinals have won the first inning in three of their last four games.
  • The Cardinals have led after 3 innings in four of their last five games as road favorites.

Total Runs Facts

  • Seven of the Cardinals’ last eight road games after going to extra innings have gone UNDER the total runs line.
  • Five of the last six games between the Cardinals and Reds have gone UNDER the total runs line.
  • There has been no run scored during the first inning in each of Kyle Leahy’s last six appearances as a starter.
  • There has been at least one run scored in the first inning in five of the last six night games between the Cardinals and Reds at Great American Ball Park.

Cincinnati Reds Player Prop Facts

  • Dane Myers has hit a home run in each of the Reds’ last two games.
  • Andrew Abbott has recorded six or more strikeouts in three of his last four appearances in night games against teams that held a winning record.
  • Sal Stewart has recorded at least one hit in each of the Reds’ last 15 games against NL Central opponents that held a winning record.

St. Louis Cardinals Player Prop Facts

  • Pedro Pages has hit a home run in three of his last five road appearances against the Reds.
  • Kyle Leahy has recorded six or more strikeouts in four of his last five appearances against NL opponents.
  • Blaze Jordan has recorded at least one hit in each of his last 11 road appearances.
  • Alec Burleson ranks T6th in the league in Hits (138) this season.

Matchup/League Facts

  • The Reds rank 30th in the league for batting average this season (.227).
  • The Reds rank 29th in the league for hits this season (941).
  • The Cardinals rank 26th in the league for slugging percentage this season (.382).
  • The Cardinals rank 5th in the league for strikeouts against this season (973).

Reds vs Cardinals Prediction

We’re getting a cheap price with the better team in the Cardinals and the better pitcher in Leahy, who has a 3.38 ERA and 1.34 WHIP. Abbott has a 4.13 ERA and 1.42 WHIP on the season, and in his last 16 innings he’s allowed 17 hits and 11 runs. Abbott has a 4.97 ERA and a .256 allowed batting average at home. I’ll side with the Cards on the road at this price.

Randy Chambers's Free Pick: St. Louis Cardinals -116

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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