Reds vs White Sox Prediction 5/14/25 MLB Picks Today

The Chicago White Sox and Cincinnati Reds meet Wednesday in MLB action at Great American Ball Park. Here’s a Reds vs White Sox Prediction. This article will include a Reds vs White Sox Pick.

Chicago White Sox Betting Preview

The Chicago White Sox are 13-29 on the year and play the Cubs, Mariners, and Rangers next. The Chicago White Sox are batting .215 on the season, have a .291 OBP, and a .322 slugging percentage. The Chicago White Sox pitching staff has a 4.01 ERA and a 1.37 WHIP. Lenyn Sosa leads the Chicago White Sox with 38 hits and 10 RBI, while Miguel Vargas and Andrew Vaughn have combined for 61 hits and 32 RBI.

Davis Martin gets the ball for the Chicago White Sox, and he is 1-4 with a 4.01 ERA and 28 strikeouts this season. This will be Martin’s first career game against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 20-23 on the year and play the Guardians, Pirates, and Cubs next. The Cincinnati Reds are batting .236 on the season, have a .318 OBP, and a .376 slugging percentage. The Cincinnati Reds pitching staff has a 3.75 ERA and a 1.18 WHIP. TJ Friedl leads the Cincinnati Reds with 43 hits and 17 RBI while Elly De La Cruz and Gavin Lux have combined for 79 hits and 48 RBI.

Nick Lodolo gets the ball for the Cincinnati Reds, and he is 3-3 with a 3.23 ERA and 38 strikeouts this season. Lodolo is 1-0 with a 2.89 ERA and 13 strikeouts in his career against the Chicago White Sox.

Why the Cincinnati Reds will win

• The White Sox have lost each of their last eight night games following a road win.
• The Reds have won seven of their last nine night games at Great American Ball Park following an extra innings loss.
• The White Sox have failed to cover the run line in seven of their last eight night games following a road win.
• The Reds have covered the run line in five of their last six games as favorites after playing the previous day.
• The Reds have led after 5 innings in three of their last four games against the White Sox.
• The Reds have led after 3 innings in three of their last four games against the White Sox.

Why the Chicago White Sox will win

• The Reds have lost each of their last six games as favorites against AL Central opponents.
• The White Sox have won each of their last four games as underdogs against National League opponents.
• The Reds have failed to cover the run line in each of their last 12 games as home favorites against American League opponents.
• The road team has covered the run line in each of the last five games between the White Sox and Reds.
• The Reds have lost the first inning in seven of their last eight Wednesday games against opponents that held a losing record.
• The Reds have trailed after 3 innings in each of their last six Wednesday night games as favorites.
• The Reds have trailed after 5 innings in each of their last seven night games at Great American Ball Park against AL Central opponents.

Cincinnati Reds Player Prop Facts

• Elly De La Cruz has hit a home run in three of the Reds’ last four games against AL opponents that held a losing record.
• Spencer Steer has recorded a Double in four of the Reds’ last five games against the White Sox.
• Elly De La Cruz has recorded a Single in each of the Reds’ last five night games against AL Central opponents that held a losing record.
• Elly De La Cruz has scored at least one run in nine of the Reds’ last 10 games against AL opponents that held a losing record.
• Nick Lodolo has recorded six or more strikeouts in four of his five previous appearances against AL opponents that held a losing record.
• Elly De La Cruz has recorded at least one hit in each of the Reds’ last 10 Wednesday games at Great American Ball Park.
• TJ Friedl has recorded at least one RBI in five of his last six appearances against AL Central opponents that held a losing record.
• Elly De La Cruz ranks T3rd in the league in Steals (14) this season.

Chicago White Sox Player Prop Facts

• Miguel Vargas has recorded a Double in three of his last four road appearances against NL Central opponents.
• Miguel Vargas has recorded at least one RBI in each of the White Sox’s last three games against NL Central opponents.
• Luis Robert has scored at least one run in each of his last six appearances against the Reds after playing the previous day.
• Luis Robert has recorded at least one Single in each of his last four appearances against the Reds after playing the previous day.
• Andrew Vaughn has recorded at least one hit in each of the White Sox’s last 11 night games against NL Central opponents that held a losing record.
• Andrew Benintendi has hit at least one home run in three of his last four appearances against NL Central opponents that held a losing record.
• Luis Robert ranks T1st in the league in Steals (16) this season.

Reds vs White Sox Prediction

The White Sox have won two straight games and have cashed some nice underdog tickets, but it still doesn’t move me. The White Sox have yet to win three straight games this season and a $100 bettor is still more than $2,000 in the hole if betting them all year. Even the worst teams in baseball win 60 games a year. Stay the course. Betting the White Sox does not make you money. Lodolo has some ugly performances and his 6.75 ERA and .299 allowed batting average in 16 home innings isn’t great. Still, backing the White Sox isn’t a profitable strategy. Give me the Reds and the RL for max betting value.