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Rockies vs Reds Prediction 4/26/25 MLB Picks Today

Cincinnati Reds (13-13) vs. Colorado Rockies (4-21)
April 26, 2025 3:10 pm EDT
The Line: Colorado Rockies 160 / Cincinnati Reds -192; Over/Under: 10.5
(Get latest betting odds)

In this article, we will formulate a Rockies vs Reds prediction for this MLB game on Saturday, April 26, at Coors Field in Denver, Colorado. Let’s take a look at the prediction for this MLB matchup.

Cincinnati Reds Betting Preview

The Cincinnati Reds (13-13, 7-7 Away) will stay on the road for the third straight series after defeating the Orioles and losing to the Marlins. Prior to those, the Reds swept the Pirates and lost to the Mariners at home. In Game 1 against the Rockies, the Reds won 8-7 thanks to Spencer Steer, Blake Dunn, and Noelvi Marte, who contributed two RBI apiece. Andrew Abbott pitched for 4.0 innings in a no-decision, allowing four runs on five hits with four strikeouts and five walks. Graham Ashcraft was credited with the win.

This season, the Reds average 5.23 runs per game (4th in the MLB) on a .245/.328/.394 slash line. Regarding pitching, the Reds’ staff has a 3.53 ERA (8th) and 1.12 WHIP (5th). Elly De La Cruz leads the Reds with a .252 batting average, five home runs, and 22 RBI this season.

The projected starting pitcher for the Reds is Hunter Greene, who is 2-2 in five starts this season, with a 2.35 ERA and 0.78 WHIP in 30.2 innings.

Colorado Rockies Betting Preview

The Colorado Rockies (4-21, 3-7 Away) lost four straight games after getting swept in a three-game series by the Kansas City Royals on the road and losing Game 1 of the current series against the Reds. Although they improved offensively with seven runs, the Rox were still left empty-handed as Cincy snatched an 8-7 victory. Jordan Beck blasted a couple of homers for the second game in a row, while Michael Toglia led the offense with three RBI. Kyle Freeland pitched for 4.1 innings in a no-decision, allowing six runs on ten hits with four strikeouts and one walk. Angel Chivilli took the loss.

This year, the Rockies average 3.36 runs per game (27th in the MLB) on a .216/.292/.355 triple-slash. When it comes to pitching, the Rockies’ staff has a 5.19 ERA (29th) and 1.57 WHIP (30th). Brenton Doyle leads the Rockies with a .295 batting average, three home runs, and 13 RBI this season.

Antonio Senzatela will take the mound for the Rockies on Saturday. The 30-year-old left-hander has a 1-3 record in five starts this year with a 4.81 ERA and 1.93 WHIP in 24.1 innings.

Total Runs Facts

  • Each of the Reds’ last four games as favorites against the Rockies have gone OVER the total runs line.
  • Six of the Rockies’ last seven day games against National League opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Reds’ last eight games as favorites against NL West opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the last 12 day games between the Reds and Rockies at Coors Field.

Matchup/League Facts

  • The Rockies rank 30th in the league for runs allowed this season (144).
  • The Rockies rank 29th in the league for batting average this season (.216).
  • The Reds rank 4th in the league for RBIs this season (131).
  • The Reds rank 5th in the league for opponent batting average this season (.212).

Rockies vs Reds Prediction

The Reds won nine of the previous ten H2H encounters, and the last time they visited Coors Field, they swept the Rockies. I know it’s tricky to back Under at this stadium, but I have faith that both Greene and Senzatela will post strong starts in this one. Greene is clearly the better pitcher, and he did struggle in his latest start against Baltimore, but didn’t allow a single run in two starts before that. Senzatela struggled against Milwaukee but responded against Washington, allowing only one run. Both should be good for five or six innings. I am going with Under.

Oliver Zivic's Free Pick: Under 10.5

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Oliver Zivic

Professional journalist and expert bettor with 20+ years of experience. I cover Football (soccer), NFL, NBA, NHL, MLB, CFB, and CBB.

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