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Rockies vs White Sox Prediction 9/26/26 MLB Picks Today

Colorado Rockies (57-103) vs. Chicago White Sox (83-77)
September 26, 2026 7:10 pm EDT
The Line: Chicago White Sox -238 / Colorado Rockies 193; Over/Under: 8
(Get latest betting odds)

In this article, we will formulate a Rockies vs White Sox Prediction for this MLB matchup on Saturday, September 26th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Preview

The Chicago White Sox have an 83-77 record this season and are sitting in the 2nd place of the AL Central. They have a 47-32 home record and are coming off a 6-1 home win against the Rockies.

The Chicago White Sox have a .236 batting average this season, .321 OBP and .404 Slugging percentage. Chicago’s pitching staff has a 4.11 ERA and 1.31 WHIP. Sam Antonacci is the team’s best hitter with a .275 batting average. Miguel Vargas leads the team in RBI with 93, while Munetaka Murakami adds a team-high 35 home runs.

Davis Martin (R) is the projected starting pitcher for the White Sox, and he has a 9-7 record, 3.84 ERA and 1.29 WHIP.

Colorado Rockies Preview

The Colorado Rockies have a 57-103 record this season and are sitting in the 5th place of the NL West. They have a 25-54 away record and are coming off a 1-6 road loss against the White Sox.

The Colorado Rockies have a .254 batting average this season, .322 OBP and .416 Slugging percentage. Colorado’s pitching staff has a 5.60 ERA and 1.53 WHIP. TJ Rumfield is the team’s best hitter with a .299 batting average. Hunter Goodman leads the team in RBI with 84, adding a team-high 39 home runs.

Jose Quintana (L) is the projected starting pitcher for the Rockies, and he has a 2-3 record, 5.40 ERA and 1.51 WHIP.

Colorado Rockies @ the Chicago White Sox Betting Trends: September 26, 2026

 

  • Probable Starting Pitcher: Davis Martin      Record this season: 9-7      ERA: 3.84
  • Home Record: 5-2
  • Last 5 against Rockies: –

Why the Chicago White Sox will win

  • The Rockies have lost each of their last 11 road games.
  • The White Sox have won each of their last six night games against NL West opponents that held a losing record.
  • The Rockies have failed to cover the run line in each of their last seven road games.
  • The White Sox have covered the run line in each of their last five night games against NL West opponents.
  • The Rockies have trailed after 3 innings in each of their last six games against opponents that held a winning record.
  • The Rockies have trailed after 5 innings in each of their last 15 night games against opponents that held a winning record.
  • The Rockies have lost the first inning in each of their last seven night games.

 

  • Probable Starting Pitcher: Jose Quintana      Record this season: 2-3      ERA: 5.40
  • Road Record: 1-2
  • Last 5 against White Sox: 1-2

Why the Colorado Rockies will win

  • The White Sox have lost each of their last six games as favorites against NL opponents following a home win.
  • The road team has won four of the Rockies’ last five games.
  • The White Sox have failed to cover the run line in each of their last six games as favorites against NL opponents following a home win.
  • The underdogs have covered the run line in four of the last five games between the Rockies and White Sox.
  • The White Sox have trailed after 5 innings in five of their last six night games at Rate Field against NL opponents.
  • The White Sox have trailed after 3 innings in four of their last five games against NL West opponents.

Total Runs Facts

  • Each of the Rockies’ last five night games as underdogs have gone UNDER the total runs line.
  • Four of the White Sox’s last five games have gone OVER the total runs line.
  • There has been at least one run scored in the first inning in each of the Rockies’ last eight night games.
  • There has been at least one run scored in the first inning in each of the White Sox’s last six night games.

Chicago White Sox Player Prop Facts

  • Munetaka Murakami has hit at least one home run in each of the White Sox’s last two home games against NL opponents that held a losing record.
  • Davis Martin has recorded five or more strikeouts in four of his last five appearances against NL West opponents.
  • Sam Antonacci has recorded at least one hit in each of the White Sox’s last eight games against NL opponents that held a losing record.
  • Munetaka Murakami ranks 10th in the league in Home Runs (35) this season.

Colorado Rockies Player Prop Facts

  • Jose Quintana has recorded a win in each of his last four appearances against AL Central opponents.
  • Jose Quintana has recorded four or more strikeouts in 17 of his last 18 appearances at Rate Field against opponents that held a winning record.
  • Connor Norby has recorded at least one hit in each of his last eight appearances with his team as an underdog against AL Central opponents.
  • Troy Johnston has hit at least one home run in three of his four previous Saturday appearances against AL teams that held a winning record.
  • TJ Rumfield ranks 3rd amongst qualified players for On Base Percentage (.389) this season.

Matchup/League Facts

  • The White Sox rank 5th in the league for runs scored this season (766).
  • The White Sox rank 5th in the league for RBIs this season (730).
  • The Rockies rank 30th in the league for ERA this season (5.60).
  • The Rockies rank 30th in the league for strikeouts this season (1098).

Rockies vs White Sox Prediction

The White Sox are 6-2 in their last 8 meetings against the Rockies and are 3-1 in their last 4 meetings in Chicago.

In this Rockies vs White Sox Prediction, the White Sox are coming as -225 home favorites. The White Sox are fighting with the Guardians for the AL Central crown and are 5-1 in their last 6 games, facing a Rockies team that is 1-8 in its last 9. They have a huge pitching edge with Davis Martin on the mound, who has just two earned runs across his last four starts and a 3.09 home ERA. On the flip side, Quintana has been terrible this season and did not look good in his first game back from injury. He sits on a 6.75 road ERA and the White Sox have been extremely good against lefties lately. Take the White Sox to win this one comfortably and cover the runline.

Nikos Lagouretos's Free Pick: Chicago White Sox -1.5

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