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Royals vs Astros Prediction 4/26/25 MLB Picks Today

Houston Astros (13-12) vs. Kansas City Royals (13-14)
April 26, 2025 7:10 pm EDT
The Line: Kansas City Royals +114 / Houston Astros -135; Over/Under: 8
(Get latest betting odds)

The Houston Astros and the Kansas City Royals meet Tuesday in MLB action from Kauffman Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Royals vs Astros Prediction.

Starting Pitching Matchup

The Houston Astros will trot out Framber Valdez for the start here, and Valdez is 1-2 with a 4.50 ERA and 26 strikeouts this season. In his last five starts against the Royals, Valdez is 2-2 with a 3.09 ERA and 32 strikeouts. Michael Wacha will start for Kansas City here, and Wacha is 0-3 with a 4.15 ERA and 20 strikeouts this season. This will be Wacha’s second career start against the Astros.

Houston Astros Recap

The Houston Astros will be out to bounce back from a 2-0 loss at the hands of the Royals in Friday’s series opener to fall to 13-12 on the year. After this series, the Astros will head home for a series against the Detroit Tigers.

Astros Have Three-Game Win Streak Snapped

Jose Altuve leads the Astros with 29 hits, including 3 home runs and 9 RBIs. Jeremy Pena also has 3 homers and 5 stolen bases, while Yordan Alvarez has 3 doubles and a team-high 13 RBIs with 18 strikeouts as well. Brendan Rodgers has 3 doubles while Jake Meyers has 4 doubles as well, and Christian Walker has also accrued a team-high 29 strikeouts so far this season. Altuve also has 3 stolen bases, while Jake Meyers has a team-high 7 stolen bases this season. Isaac Paredes also has a team-high 4 home runs with 13 RBIs of his own, and Cam Smith has contributed 3 homers and 10 RBIs.

Why the Houston Astros will win

  • The Astros have won each of their last eight games following a road loss.
  • The Royals have lost eight of their last nine night games against American League opponents that held a winning record.
  • The Astros have covered the run line in each of their last 10 road games against American League opponents following a loss.
  • The Royals have failed to cover the run line in five of their last six night games following a win.

Houston Astros Player Prop Facts

  • Isaac Paredes has hit a home run in four of the Astros’ last seven games against AL opponents.
  • Yainer Diaz has recorded an RBI in each of his last four road appearances against the Royals.
  • Framber Valdez has recorded a win in four of his last five appearances with the Astros as road favorites against AL opponents.
  • Yainer Diaz has scored a run in each of his last six appearances against the Royals.
  • Framber Valdez has recorded five or more strikeouts in each of his last 10 appearances against AL Central opponents that held a losing record.
  • Isaac Paredes has recorded at least one hit in each of the Astros’ last nine games against AL opponents.
  • Victor Caratini has recorded at least one Single in each of his last seven appearances in night games against AL Central teams that held a losing record.

Kansas City Royals Recap

The Kansas City Royals come into this one looking to build on their series-opening win over the Astros on Friday to improve to 13-14 on the year. After this series, the Royals will head on the road for a series against the Tampa Bay Rays.

Royals Win Five In A Row

Bobby Witt Jr. has a team-high 33 hits with 10 doubles and 8 stolen bases, while Vinnie Pasquantino has 18 hits with 4 doubles, a triple, 2 home runs, and 15 RBIs. Maikel Garcia added 25 hits with 6 doubles, 2 home runs, and 10 RBIs, and Salvador Perez also has 2 home runs and 14 RBIs, but also has the unfortunate distinction of leading the Royals with 23 strikeouts so far this season.

Why the Kansas City Royals will win

  • The Royals have won each of their last seven games as underdogs against the Astros following a win.
  • The Astros have lost four of their last five games as road favorites.
  • The Royals have covered the run line in each of their last seven games against the Astros following a win.
  • The Astros have failed to cover the run line in seven of their last eight night games against the Royals following a loss.

Kansas City Royals Player Prop Facts

  • Jonathan India has hit a home run in four of his last seven appearances against AL West opponents that held a winning record.
  • Bobby Witt Jr. has recorded a Double in three of the Royals’ last four home games against AL opponents.
  • Hunter Renfroe has recorded at least one RBI in four of his last five appearances in night games against AL West teams that held a winning record.
  • Michael Wacha has recorded five or more strikeouts in four of his last five appearances against AL West opponents.
  • Bobby Witt Jr. has scored at least one run in eight of the Royals’ last 10 home games against the Astros.
  • Vinnie Pasquantino has recorded at least one hit in each of his last nine home appearances against AL West opponents that held a winning record.
  • Bobby Witt Jr. has recorded at least one Single in each of the Royals’ last four home games against AL West opponents that held a winning record.
  • Bobby Witt Jr. ranks T5th in the league in Steals (8) this season.

Total Runs Facts

  • Each of the Astros’ last seven games after playing the previous day have gone UNDER the total runs line.
  • Each of the Royals’ last six home games against American League opponents have gone UNDER the total runs line.

Royals vs Astros Prediction

I’m on the under in this game. I think game one on Friday was kind of a microcosm of what we’ve seen from these two teams so far this season, just solid pitching, but two offenses that have been inconsistent from a production standpoint. They have been hard to trust in terms of knowing what they’re going to put up on a game-to-game basis. I mean, the Royals have scored 4 runs or fewer in 18 of their last 20 games, and the Astros have been struggling as well since day one, for the most part. I think this is going to be another low-scoring battle. Give me the under.

Chris Ruffolo's Free Pick: Under 8

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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