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Royals vs Orioles Prediction 4/6/25 MLB Picks Today

Baltimore Orioles (4-5) vs. Kansas City Royals (3-5)
April 6, 2025 2:10 pm EDT
The Line: Kansas City Royals -108 / Baltimore Orioles -112; Over/Under: 8.5
(Get latest betting odds)

In this article we will formulate a Royals vs Orioles prediction for this MLB game on Sunday, April 6th at Kauffman Stadium in Kansas City, Missouri. Let’s take a look at the prediction for this MLB matchup. 

Kansas City Royals Betting Preview

The Kansas City Royals are 3-5 this year after they lost game two by a score of 8-1 on Saturday, but they did win game one by a score of 8-2 on Friday. In that game two loss, the Royals fell behind in the second inning and they never made it a game, but did score in the sixth inning to avoid the shutout. The Royals recorded five hits in the game and they were led by Witt Jr., who went 1-4 with one home run and one RBI in the loss. Kansas City started Wacha, who allowed six hits and four earned runs over 5.2 innings, while Long and Stratton also allowed two earned runs a piece in relief. 


Prior to this series, the Royals lost two out of three against the Brewers and two out of three against the Guardians. The Kansas City pitching staff has a 3.68 ERA with a 1.34 WHIP and a .243 opponent batting average, while the offense has scored 32 runs with a .219 batting average and a .293 on base percentage this season. Vinnie Pasquantino has led Kansas City with one home run and seven RBIs, while Maikel Garcia has added two home runs and six RBIs this year. The projected starting pitcher for Kansas City is Kris Bubic, who is 1-0 with a 0.00 ERA and a 0.83 WHIP over 6.0 innings pitched this season. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 4-5 this season after they won game two in this series by a score of 8-1. Baltimore led 2-0 early in the game and they added four in the sixth inning to put the game away. The Orioles recorded 12 hits in the game and they were led by O’Neill, Sanchez, and Holliday, who all had two RBIs in the win. Baltimore started Sugano, who allowed five hits and one earned run over 5.1 innings, while Baker, Akin, and Bowman combined for 3.2 shutout innings out of the bullpen. 

Prior to this series, the Orioles lost two out of three against the Red Sox and split four games with the Blue Jays. The Baltimore pitching staff has a 4.73 ERA with a 1.37 WHIP and a .259 opponent batting average, while their offense has scored 46 runs with a .274 batting average and a .337 on base percentage this season. Cedric Mullins has led Baltimore with three home runs and 11 RBIs, while Tyler O’Neill has added one home run and seven RBIs this year. The projected starting pitcher for Baltimore is Cade Povich, who is 0-0 with a 6.23 ERA and a 1.62 WHIP over 4.1 innings pitched this season. 

Why the Royals will beat the Orioles

  • The underdogs have won each of the last five games between the Orioles and Royals.
  • The Orioles have lost each of their last five games as favorites against AL Central opponents.
  • The underdogs have covered the run line in nine of the Royals’ last 10 games at Kauffman Stadium.
  • The Orioles have failed to cover the run line in each of their last five games as favorites against AL Central opponents.
  • The Orioles have lost the first inning in three of their last four games as favorites against American League opponents.
  • The Orioles have trailed after 5 innings in five of their last six road games against American League opponents that held a losing record.

Total Runs Facts

  • Each of the Orioles’ last four games after playing the previous day have gone OVER the total runs line.
  • Twelve of the Royals’ last 14 day games against AL East opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Royals’ last nine day games at Kauffman Stadium.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Orioles’ last four games as favorites.

Kansas City Royals Player Prop Facts

  • Hunter Renfroe has recorded at least one Single in each of his last eight appearances against AL opponents that held a losing record.
  • Bobby Witt Jr. has hit a home run in each of the Royals’ last two day games against AL East opponents that held a losing record.
  • Mark Canha has recorded a Double in four of his last five home appearances against AL East opponents.
  • Vinnie Pasquantino has recorded at least one RBI in eight of his last nine appearances with the Royals as home underdogs against AL opponents.
  • Bobby Witt Jr. has recorded at least one hit in each of the Royals’ last 23 home games against opponents that held a losing record.
  • Bobby Witt Jr. has scored at least one run in 15 of the Royals’ last 16 home games against AL opponents that held a losing record.

Baltimore Orioles Player Prop Facts

  • Tyler O’Neill has hit a home run in four of his last seven appearances with his team as a road favorite against the Royals.
  • Ramon Laureano has recorded at least one RBI in each of his last four appearances with his team as a road favorite against AL opponents.
  • Ramon Urias has scored a run in each of his last four appearances with the Orioles as road favorites.
  • Ramon Urias has recorded at least one Single in each of his last six appearances.
  • Cedric Mullins has recorded at least one hit in each of the Orioles’ last 12 day games.

Royals vs Orioles Prediction 

These two teams have both won one game in blowout fashion so far in this series and each side will look for the series win here. Kansas City has lost three of their last four games and they have scored a total of three runs in those three losses. Baltimore has also lost three of their last four games and they have allowed eight runs in two of those games. The Royals got a very good first outing from Bubic, while Povich allowed five hits and three earned runs in 4.1 innings against Boston last time out. Povich has been way too inconsistent for my liking, so I will take the Royals at home here. 

David Racey's Free Pick: Royals ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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