San Diego Padres vs Colorado Rockies Prediction 4/10/26 MLB Picks Today

Starting Pitching Matchup

The Colorado Rockies will send out Tomoyuki Sugano for the start here and Sugano is 1-0 with a 1.69 ERA and 9 strikeouts this season. This will be Sugano’s first career start against Colorado. Walker Buehler will start here for San Diego and is 0-1 with a 9.45 ERA and 7 strikeouts this season. In his last five starts against the Rockies, Buehler is 1-2 with a 7.88 ERA and 25 strikeouts.

Colorado Rockies Recap

The Colorado Rockies come into this game looking to bounce back from a 7-3 loss at the hands of the Padres in Thursday’s series opener to fall to 6-7 this season. After this series, the Rockies will head on the road for a game against the Houston Astros.

Rockies Have Four-Game Win Streak Snapped

TJ Rumfield has 14 hits with a double, a triple, 2 home runs and 8 RBIs while Ezequiel Tovar has 14 hits with 6 doubles, a home run and 6 RBIs. Hunter Goodman’s added 11 hits with a double, 2 home runs and 4 RBIs and Jordan Beck has 4 RBIs as well on the year. Troy Johnston has 13 hits with 3 doubles, 2 home runs and 6 RBIs. Willi Castro also has 10 hits with 3 doubles, a home run and 7 RBIs.

San Diego Padres Recap

The San Diego Padres come into this game looking to build on their win over the Rockies from Thursday’s matchup to sit at 7-6 this season. After this series, the Padres will take on the Seattle Mariners in a series at home.

Padres Win 6 Of Last 8

Jackson Merrill has 9 hits with 2 doubles, 2 home runs and 7 RBIs while Ramon Laureano has 11 hits with 2 doubles, 2 home runs and 8 RBIs as well on the year. Fernando Tatis Jr. has 10 hits with 3 doubles and 5 RBIs and Xander Bogaerts has 13 hits with 2 doubles, 2 home runs and 8 RBIs. Manny Machado also has 8 hits with 2 doubles, a home run and 5 RBIs as well on the year.

Colorado Rockies @ San Diego Padres Betting Trends: April 10, 2026

• Probable Starting Pitcher: Walker Buehler      Record this season: 0-1      ERA: 9.45
• Home Record: 0-1
• Last 5 against Rockies: 1-2

Why the San Diego Padres will win

• The Rockies have lost each of their last nine road games against National League opponents.
• The Padres have won nine of their last 10 home games against the Rockies.
• The home team has covered the run line in each of the Rockies’ last six games.
• The Rockies have failed to cover the run line in eight of their last nine games at Petco Park.
• The Rockies have trailed after 3 innings in 12 of their last 13 road games against NL West opponents that held a winning record.
• The Rockies have trailed after 5 innings in seven of their last eight games at Petco Park against opponents that held a winning record.

• Probable Starting Pitcher: Tomoyuki Sugano      Record this season: 1-0      ERA: 1.69
• Road Record: 0-0
• Last 5 against Padres: –

Why the Colorado Rockies will win

• The Rockies have won four of their last five games as underdogs.
• The Padres have lost six of their last seven Friday games as favorites.
• The Rockies have covered the run line in each of their last seven games following a loss.
• The Padres have failed to cover the run line in four of their last five games as favorites after going to extra innings.
• The Padres have lost the first inning in three of their last four night games against opponents that held a losing record.
• The Padres have trailed after 3 innings in each of their last four night games against opponents that held a losing record.
• The Padres have trailed after 5 innings in each of their last four night games against opponents that held a losing record.

Total Runs Facts

• Six of the Rockies’ last seven road games following an extra innings loss have gone UNDER the total runs line.
• Four of the Padres’ last five games have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Padres’ last seven games.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Rockies’ last four road games.

San Diego Padres Player Prop Facts

• Manny Machado has hit a home run in three of his last four appearances against the Rockies after playing the previous day.
• Manny Machado has recorded at least one hit in each of the Padres’ last 10 Friday games at Petco Park.

Colorado Rockies Player Prop Facts

• Brenton Doyle has hit a home run in two of the Rockies’ last three games against NL West opponents.
• Ezequiel Tovar has recorded at least one hit in each of the Rockies’ last seven road games.

Matchup/League Facts

• The Padres rank T2nd in the league for doubles this season (28).
• The Padres rank T2nd in the league for home runs allowed this season (7).
• The Rockies rank T28th in the league for strikeouts against this season (133).
• The Rockies rank T27th in the league for walks this season (35).

Colorado Rockies vs. San Diego Padres Prediction

I’m on the Rockies here. I think that Walker Buehler is the weak link of the Padres’ rotation, as he’s been getting shelled early on this season and I don’t really expect that to change here. The Rockies normally have a one game slump after coming out of Colorado as it takes time for the bats to adjust to the altitude change, but all in all, I think that the Rockies bounce back and get a win here. Give me Colorado.