MLB Picks

San Diego Padres vs Houston Astros MLB Picks, Odds, Predictions 9/3/2021

Houston Astros (78-55) vs. San Diego Padres (71-63)
September 3, 2021 10:10 pm EDT
The Line: San Diego Padres +134 / Houston Astros -145; Over/Under: 8.5
(Get latest betting odds)

The Houston Astros and the San Diego Padres meet in MLB action from Petco Park on Friday night.

The Houston Astros will look to Michael Brantley and Alex Bregman each had two hits while Jose Altuve chipped in a double. Carlos Correa, Yuli Gurriel, Jake Meyers and Martin Maldonado each had base hits to finish off Houston’s offense in the shutout defeat. Jake Odorizzi took the loss, falling to 6-7 on the year after allowing just one run on two hits while striking out seven over five innings of work. Jose Urquidy will start here and is 6-3 with a 3.38 ERA and 66 strikeouts this season.


The San Diego Padres will try to rebound from an 8-3 loss at the hands of Arizona last time out. All of San Diego’s scoring came via home runs, as Wil Myers had a two-run home run while Trent Grisham had a solo home run. Manny Machado, Fernando Tatis Jr. and Eric Hosmer each had a double to round out the offense for the Padres in defeat. Yu Darvish took the loss, falling to 7-9 after allowing five earned runs on eight hits while striking out three over 2.2 innings of work. Jake Arrieta will start here and is 5-12 with a 7.13 ERA and 77 strikeouts this season.

Houston is 5-1 in their last 6 games overall and 4-1 in their last 5 road games while the under is 3-0-1 in their last 4 games following an off day. San Diego is 11-4 in their last 15 interleague games and 4-9 in their last 13 games following a loss while the over is 5-0 in their last 5 interleague games as an underdog.

This line feels a bit weird, but I’m not doing near the Padres in this spot. San Diego’s been struggling to begin with and now send Jake Arrieta to the mound and needless to say, he has not been a pitcher I’d want on my staff this season. We haven’t seen a ton of Jose Urquidy, but he’s been serviceable and the Astros are just the hotter hitting team right now. Give me the Astros here.

Chris Ruffolo's Free Pick: Houston -145

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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