San Diego Padres vs Milwaukee Brewers Prediction 8/12/26 MLB Picks Today

The Milwaukee Brewers and the San Diego Padres meet Wednesday in MLB action from Petco Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Milwaukee Brewers vs. San Diego Padres prediction.

Starting Pitching Matchup

The Milwaukee Brewers will send out Dustin May for the start here and May is 6-7 with a 4.30 ERA and 111 strikeouts this season. Robbie Ray will start for the Padres and is 10-7 with a 3.24 ERA and 109 strikeouts this season.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to bounce back from an 11-2 loss at the hands of teh Padres last time out to sit at 74-46 this season. After this series, After this series, the Brewers will head on the road for a set against the Los Angeles Dodgers.

Brewers Drop Back-To-Back Games

Entering Tuesday, William Contreras has 111 hits with 17 doubles, 11 home runs and 59 RBIs while Brice Turang’s added 119 hits with 27 doubles, 3 triples, 16 homers and 74 RBIs. Jake Bauers has 97 hits with 17 doubles, 21 home runs and 67 RBIs and Sal Frelick’s added 65 hits with 4 home runs and 34 RBIs this season. Garrett Mitchell has 87 hits with 24 doubles and 50 RBIs this season.

San Diego Padres Recap

The San Diego Padres come into this game looking to add on to their win over the Brewers from Tuesday to sit at 64-57 this season. After this series, the Padres will head on the road for a series against the Cleveland Guardians.

Padres Win 4 In A Row

Going into Tuesday, Jackson Merrill has 111 hits with 18 doubles, 19 home runs and 61 RBIs while Gavin Sheets has 70 hits with 15 doubles, 15 home runs and 44 RBIs as well on the year. Fernando Tatis Jr. has 130 hits with 25 doubles, 11 home runs and 54 RBIs and Xander Bogaerts has 86 hits with 11 doubles, 9 home runs and 41 RBIs. Manny Machado also has 91 hits with 20 doubles, 23 home runs and 70 RBIs as well on the year.

Milwaukee Brewers @ San Diego Padres Betting Trends: August 12, 2026

• Probable Starting Pitcher: Robbie Ray      Record this season: 10-7      ERA: 3.24
• Home Record: 6-2
• Last 5 against Brewers: 3-0

Why the San Diego Padres will win

• The underdogs have won each of the Brewers’ last seven games at Petco Park.
• The Brewers have lost seven of their last eight games as road favorites against the Padres following a loss.
• The underdogs have covered the run line in each of the Brewers’ last seven games at Petco Park.
• The Brewers have failed to cover the run line in 12 of their last 13 games as favorites against the Padres following a road loss.
• The Brewers have trailed after 5 innings in six of their last seven day games against NL West opponents.
• The Brewers have trailed after 3 innings in six of their last seven road day games.

• Probable Starting Pitcher: Dustin May      Record this season: 6-7      ERA: 4.30
• Road Record: 2-4
• Last 5 against Padres: 2-1

Why the Milwaukee Brewers will win

• The Brewers have won five of their last six games against NL West opponents following a loss.
• The Padres have lost five of their last six day games against the Brewers following a win.
• The Padres have failed to cover the run line in each of their last five day games against NL Central opponents following a win.
• The Brewers have covered the run line in each of their last three day games against the Padres following a loss.
• The Brewers have led after 3 innings in five of their last six games against NL West opponents that held a winning record.
• The Brewers have led after 5 innings in five of their last six games against the Padres.

Total Runs Facts

• Five of the Brewers’ last six games against National League opponents have gone UNDER the total runs line.
• Four of the Padres’ last five home games against NL Central opponents have gone OVER the total runs line.
• There has been no run scored during the first inning in each of the Brewers’ last seven road games against National League opponents.
• There has been no run scored during the first inning in each of the Padres’ last seven games as home underdogs against National League opponents.

San Diego Padres Player Prop Facts

• Jackson Merrill has hit a home run in three of the Padres’ last four games.
• Robbie Ray has recorded a win in each of his last four appearances with his team as an underdog against NL opponents.
• Robbie Ray has recorded six or more strikeouts in six of his last seven home appearances against NL Central opponents.
• Jackson Merrill has recorded at least one hit in each of his eight previous home appearances against the Brewers.
• Fernando Tatis Jr. ranks 7th in the league in Hits (131) this season.

Milwaukee Brewers Player Prop Facts

• Jackson Chourio has hit a home run in each of the Brewers’ last two day games.
• Dustin May has recorded a win in four of his last five appearances with his team as a favorite against NL West opponents .
• Dustin May has recorded six or more strikeouts in four of his last five road appearances against NL opponents.
• Brice Turang has recorded at least one hit in each of the Brewers’ last seven day games.

Matchup/League Facts

• The Padres rank T3rd in the league for steals this season (119).
• The Padres rank 24th in the league for slugging percentage this season (.389).
• The Brewers rank 30th in the league for home runs this season (110).
• The Brewers rank 2nd in the league for walks this season (495).

Milwaukee Brewers vs. San Diego Padres Prediction

I’m backing the Padres here. I just don’t love the pickup of Dustin May for the Brewers and I think with the way the Padres are swinging the bat, they’ll be able to get to him here. On the other side, the Brewers have been hit or miss at times against lefties, and I look for Robbie Ray to have a better start in his second outing for his new club. Give me the Padres.