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St. Louis Cardinals vs Baltimore Orioles Prediction 5-22-24 Picks

Baltimore Orioles (29-16) vs. St. Louis Cardinals (21-26)
May 22, 2024 1:15 pm EDT
The Line: St. Louis Cardinals +114 / Baltimore Orioles -135; Over/Under: 8.5
(Get latest betting odds)

In this article, we will formulate a St. Louis Cardinals vs Baltimore Orioles Prediction for this MLB Game on Wednesday, May 22nd at Busch Stadium. 

Orioles Need a Strong Start from Means

The Orioles are averaging 4.98 runs while their pitching is giving up 3.76 runs per game. The offense is ranked 4th in the league while the pitching is ranked 9th. They are averaging 1.53 home runs per game which is the best in baseball. Gunnar Henderson has hit four home runs and driven in 16 RBIs. Getting the start for the Orioles will be John Means who sits with a 2-0 record and an ERA of 3.06. In his last start against the Seattle Mariners, he went six innings giving up six hits and two runs. If Means can have another strong start, the Orioles should be in good shape to secure the win. 

Can Cardinals Turn Around the Season? 

The Cardinals are averaging 3.85 runs while their pitching is giving up 4.83 runs per game The offense is ranked 24th in the league while the pitching is ranked 25th. This is a team that hasn’t hit a ton of home runs. Brendan Donovan has been the top player for Cardinals, hitting four home runs and driving in 21 RBIs so far this season. Getting the start for the Cardinals will be Kyle Gibson, who sits with a 3-2 record and an ERA of 4.09. In his last start against the Boston Red Sox, he went six innings giving up eight hits and five runs. If the Cardinals want any chance to find success in this game, they are going to need to have a much better start from Gibson. 

Why the Baltimore Orioles will win

  • The Orioles have won each of their last six day games following a loss.
  • The Cardinals have lost each of their last four day games at Busch Stadium following a win.
  • The Cardinals have failed to cover the run line in each of their last four day games against American League opponents.
  • The Orioles have covered the run line in five of their last six day games against National League opponents following a road loss.
  • The Orioles have led after 5 innings in each of their last five road day games.
  • The Cardinals have trailed after 3 innings in each of their last five day games.
  • The Cardinals have lost the first inning in each of their last five Wednesday home games.

St. Louis Cardinals Player Prop Facts

  • Willson Contreras has hit at least one home run in three of his five previous appearances against the Orioles after not playing the previous day.
  • Lance Lynn has recorded a win in three of his last four appearances in day games against teams that held a winning record.
  • Lars Nootbaar has recorded at least one RBI in each of the Cardinals’ last four games as underdogs.
  • Nolan Arenado has recorded at least one Single in each of his last 10 Wednesday day appearances.
  • Willson Contreras has recorded at least one hit in each of his last 11 appearances with his team as an underdog against AL East opponents.
  • Lance Lynn has recorded five or more strikeouts in each of his last 15 appearances with his team as a home underdog against AL opponents.
  • Nolan Arenado has recorded at least one total base in each of his last 11 appearances with the Cardinals as home underdogs against AL opponents.
  • Willson Contreras has scored at least one run in each of his last seven home appearances.

Baltimore Orioles Player Prop Facts

  • Gunnar Henderson has hit a home run in each of the Orioles’ last four games.
  • Adley Rutschman has recorded at least one Single in each of the Orioles’ last 10 games as road favorites.
  • Kyle Bradish has recorded a win in three of his last four appearances against NL opponents.
  • Gunnar Henderson has recorded at least one RBI in each of the Orioles’ last four games.
  • Adley Rutschman has recorded at least one hit in each of the Orioles’ last 10 games as road favorites.
  • Kyle Bradish has recorded six or more strikeouts in each of his last seven road appearances.
  • Adley Rutschman has recorded at least one total base in each of the Orioles’ last 10 games as road favorites.
  • Gunnar Henderson has scored at least one run in seven of the Orioles’ last eight road games against opponents that held a losing record.

Matchup/League Facts

  • The St. Louis Cardinals rank 28th in the league for runs scored this season (181).
  • The St. Louis Cardinals rank 28th in the league for RBI’s this season (169).
  • The Baltimore Orioles rank T1st in the league for home runs this season (69).
  • The Baltimore Orioles rank 1st in the league for slugging percentage this season (.441).

Baltimore Orioles vs St. Louis Cardinals Prediction 

Means sits with an ERA of 3.06, and he’s going to lockdown again here. In his last start, he gave up only two runs, and he’s going to lock down again here. Gibson in his last start gave up five runs, and he’s going to struggle here. The Orioles are averaging 4.98 runs per game, and they are going to have no issue running up the score here. This game will get out of hand early. Back the Orioles on the run line. 

Shane Mickle's Free Pick: Orioles -1.5

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Shane Mickle

Sports is about all Shane knows in this life! He has a passion for sports and writing, which makes working for Sportschatplace a perfect job for him! If you find him cheering for a team it's usually a Minnesota team, or the Kansas Jayhawks!

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