Tigers vs Giants Prediction 5/28/25 MLB Picks Today

In this article, we will formulate a Tigers vs Giants prediction for this MLB game on Wednesday, May 28th at Comerica Park in Detroit, Michigan. Let’s take a look at the prediction for this MLB matchup.

Detroit Tigers Betting Preview

The Detroit Tigers are 36-20 this season after they won the first two games in this series by a score of 3-1 in each game. In their game two win, Detroit scored three runs in the first three innings, which was enough for the win, but they didn’t score over the final five innings. The Tigers recorded seven hits in the game, and they were led by Greene, who went 3-4 with two RBIs in the win. Detroit started Flaherty, who allowed two hits and zero earned runs over 6.0 innings for the win, while Vest picked up the save. 

Prior to this series, the Tigers lost three out of four against the Guardians, but did win two out of three against the Cardinals before that. Detroit has won three games in a row, and they are currently first in the AL Central standings. The Detroit pitching staff has a 3.23 ERA with a 1.15 WHIP and a .224 opponent batting average, while the offense has scored 284 runs with a .253 batting average and a .325 on-base percentage this season. Spencer Torkelson has led Detroit with 13 home runs and 40 RBIs, while Riley Greene has added 12 home runs and 38 RBIs this year. The projected starting pitcher for Detroit is Jackson Jobe, who is 4-1 with a 4.06 ERA and a 1.42 WHIP over 44.1 innings pitched this season. 

San Francisco Giants Betting Preview

The San Francisco Giants are 31-24 this year after they lost game two by a score of 3-1 on Tuesday night. San Francisco didn’t generate much at the plate, but they did score in the ninth inning to avoid the shutout. The Giants recorded six hits and they committed one error in the game, while they were led by Flores, who went 1-4 with one RBI in the loss. San Francisco started Webb, who allowed seven hits and three earned runs over 6.0 innings in the loss, while Beck pitched the final two innings. 

Prior to this series, the Giants won two out of three against the Nationals, but lost two out of three against the Royals before that. San Francisco has lost three of their last four games, and they are currently third in the NL West standings. The San Francisco pitching staff has a 3.25 ERA with a 1.20 WHIP, and a .234 opponent batting average, while the offense has scored 239 runs with a .230 batting average and a .307 on-base percentage this season. Wilmer Flores has led San Francisco with 10 home runs and 45 RBIs, while Matt Chapman has added nine home runs and 25 RBIs this year. The projected starting pitcher for San Francisco is Landen Roupp, who is 3-3 with a 3.63 ERA and a 1.40 WHIP over 52.0 innings pitched this year. 

Why the Tigers will beat the Giants

• The Giants have lost each of their last six games at Comerica Park.
• The Tigers have won each of their last six games against NL West opponents.
• The Tigers have covered the run line each of their last nine day games against teams that held a winning record.
• The Giants have failed to cover the run line each of their last nine games against American League opponents that held a winning record.
• The Giants have trailed after 3 innings in each of their last six Wednesday games against American League opponents that held a winning record.
• The Giants have lost the first inning in five of their last six day games against American League opponents that held a winning record.
• The Tigers have led after 5 innings in eight of their last nine games as home favorites against NL West opponents.

Why the Giants will beat the Tigers

• The Giants have won nine of their last 12 games as road underdogs following a road loss.
• The Tigers have lost seven of their last 10 games as favorites against National League opponents following a home win.
• The Giants have covered the run line in each of their last eight games as underdogs against American League opponents following a loss.
• The Tigers have failed to cover the run line in six of their last seven games as favorites following a win.
• The Giants have led after 3 innings in six of their last seven games as underdogs against AL Central opponents.
• The Giants have led after 5 innings in six of their last seven games as underdogs against AL Central opponents.

Total Runs Facts

• Each of the Tigers’ last six games as favorites against the Giants have gone UNDER the total runs line.
• Nine of the Giants’ last 10 games have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the Tigers’ last 11 day games at Comerica Park.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Giants’ last 12 day games against American League opponents.

Detroit Tigers Player Prop Facts

• Colt Keith has recorded a Double in four of his last five appearances with the Tigers as favorites.
• Riley Greene has recorded at least one RBI in 10 of the Tigers’ last 12 games as home favorites against NL opponents.
• Riley Greene has recorded at least one Single in each of the Tigers’ last six games against NL opponents that held a winning record.
• Spencer Torkelson has recorded at least one hit in each of the Tigers’ last nine day games.
• Zach McKinstry has scored at least one run in seven of his last eight appearances against NL West opponents.
• Matt Vierling has hit a home run in three of his last four Wednesday day appearances at Comerica Park.

San Francisco Giants Player Prop Facts

• Wilmer Flores has recorded an RBI in each of the Giants’ last four road games against opponents that held a winning record.
• Matt Chapman has scored at least one run in each of the Giants’ last six games as road underdogs.
• Heliot Ramos has recorded at least one Single in each of his last 12 appearances against AL opponents.
• Heliot Ramos has recorded at least one hit in each of his last 12 appearances against AL opponents.
• Tom Murphy has hit a home run in two of his last three appearances against AL Central opponents.
• Tom Murphy has recorded a Double in four of his last five road appearances against AL Central opponents.

Tigers vs Giants Prediction 

Detroit was able to pick up another 3-1 win on Tuesday night, and they will look for the series sweep here. The Tigers are 20-8 at home this year, while the Giants are 14-15 on the road. San Francisco has dropped three of their last four games, and they have scored one run or fewer in all three of those losses. The Giants are starting Roupp, who has allowed two earned runs or fewer in four straight outings. The Tigers are going with Jobe, who has allowed two earned runs or fewer in three straight starts. Both of these teams have been lower scoring in recent games, and each starting pitcher has been very good, so I like the under here.