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Tigers vs Yankees Prediction 6/22/26 MLB Picks Today

NY Yankees (46-30) vs. Detroit Tigers (33-44)
June 22, 2026 6:10 pm EDT
The Line: Detroit Tigers 113 / NY Yankees -136; Over/Under: 8.5
(Get latest betting odds)

The New York Yankees and Detroit Tigers meet Monday in MLB action at Comerica Park. Here’s a Tigers vs Yankees Prediction. This article will include a Tigers vs Yankees Pick.

New York Yankees Betting Preview

The New York Yankees are 46-30 on the year and play the Red Sox and Tigers next. The New York Yankees are batting .245 on the season and have a .332 OBP and a .439 slugging percentage. The New York Yankees’ pitching staff has a 3.35 ERA and a 1.18 WHIP. Ben Rice leads the New York Yankees with 77 hits and 53 RBI, while Cody Bellinger and Jazz Chisholm Jr. have combined for 135 hits and 80 RBI.

Gerrit Cole gets the ball for the New York Yankees, and he is 2-1 with a 2.57 ERA and 24 strikeouts this season. Cole is 10-1 with a 1.84 ERA and 106 strikeouts in his career against the Detroit Tigers.

Detroit Tigers Betting Preview

The Detroit Tigers are 33-44 on the year and play the Astros and Yankees next. The Detroit Tigers are batting .235 on the season and have a .315 OBP and a .393 slugging percentage. The Detroit Tigers’ pitching staff has a 3.83 ERA and a 1.27 WHIP. Riley Greene leads the Detroit Tigers with 81 hits and 33 RBI, while Dillon Dingler and Kevin McGonigle have combined for 148 hits and 81 RBI.

Framber Valdez gets the ball for the Detroit Tigers, and he is 3-5 with a 4.09 ERA and 67 strikeouts this season. Valdez is 0-2 with a 7.22 ERA and 29 strikeouts in his career against the New York Yankees.

Why the Detroit Tigers will win

  • The Tigers have won each of their last four games as underdogs against AL East opponents.
  • The Yankees have lost three of their last four games as favorites.
  • The Tigers have covered the run line each of their last six games against AL East opponents that held a winning record.
  • The Yankees have failed to cover the run line in each of their last four games at Comerica Park.
  • The Tigers have won the first inning in each of their last four night games against AL East opponents.
  • The Tigers have led after 3 innings in each of their last four games against AL East opponents.
  • The Tigers have led after 5 innings in each of their last five games against AL East opponents.

Why the New York Yankees will win

  • The Yankees have won each of their last 11 games against AL Central opponents that held a losing record.
  • The Tigers have lost each of their last four games after going to extra innings.
  • The Tigers have failed to cover the run line in each of their last six night games against the Yankees at Comerica Park following a home win.
  • The Yankees have covered the run line in eight of their last nine night games at Comerica Park following a loss.
  • The Yankees have led after 3 innings in each of their last six Monday games as favorites.
  • The Yankees have led after 5 innings in each of their last 11 games against AL Central opponents that held a losing record.
  • The Yankees have won the first inning in each of their last three night games at Comerica Park.

Total Runs Facts

  • Each of the Tigers’ last four home games against AL East opponents has gone UNDER the total runs line.
  • Each of the Yankees’ last three games as favorites against the Tigers has gone OVER the total runs line.
  • There has been at least one run scored in the first inning in each of the Tigers’ last four games against AL East opponents.
  • There has been no run scored during the first inning in four of Gerrit Cole’s last five appearances as a starter.

Detroit Tigers Player Prop Facts

  • Riley Greene has hit a home run in each of the Tigers’ last two night games against AL East opponents that held a winning record.
  • Framber Valdez has recorded a win in three of his last four home appearances against AL East opponents that held a winning record.
  • Framber Valdez has recorded seven or more strikeouts in each of his last four home appearances against AL East opponents that held a winning record.
  • Parker Meadows has recorded at least one hit in each of his 16 previous appearances in night games against AL East teams that held a winning record.
  • Dillon Dingler ranks 10th amongst qualified players for Slugging Percentage (.546) this season.

New York Yankees Player Prop Facts

  • Cody Bellinger has hit a home run in three of the Yankees’ last four road games against AL Central opponents that held a losing record.
  • Gerrit Cole has recorded a win in each of his last six road appearances against AL opponents that held a losing record.
  • Gerrit Cole has recorded seven or more strikeouts in each of his last six appearances against opponents that held a losing record.
  • Trent Grisham has recorded at least one hit in each of his last seven appearances.
  • Ben Rice ranks 2nd amongst qualified players for Slugging Percentage (.616) this season.

Matchup/League Facts

  • The Tigers rank T3rd in the league for triples this season (15).
  • The Tigers rank 28th in the league for steals this season (27).
  • The Yankees rank 1st in the league for home runs this season (114).
  • The Yankees rank 1st in the league for slugging percentage this season (.439).

Tigers vs Yankees Prediction

The Tigers still have issues stringing wins together, and Valdez has been hittable this season with a 4.09 ERA and 1.35 WHIP. Cole has pitched just 28 innings, but he’s looked sharp with a 2.57 ERA and 1.00 WHIP. Cole has also owned the Tigers throughout his career, and he’s holding current Detroit hitters to a .200 batting average with 21 strikeouts in 45 at-bats. We’re laying a cheap price. I’m rolling with the Yankees behind their ace.

Randy Chambers's Free Pick: NY Yankees -136

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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