Twins vs Athletics Prediction 6/4/25 MLB Picks Today

The Minnesota Twins are visiting the Athletics on Wednesday, June 4^th at the Sutter Health Park in the second game of this series, with the Twins having a 2-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Twins vs Athletics Prediction. We will examine:

The Athletics’ recent form and player performance

The Minnesota Twins’ recent form and player performance

Recent betting trends and streaks involving the Athletics

Recent betting trends and streaks involving the Minnesota Twins

Recent betting trends in games played between the Minnesota Twins vs Athletics

A summary that ties it all together and produces a favorable betting outcome for the Minnesota Twins vs Athletics game

Athletics Preview

The Athletics have a 23-39 record this season and are sitting in last place in the AL West. The Athletics have a 9-21 home record and are 35-22 in over/under. They are coming off a 3-10 home defeat by the Twins, and have 8 consecutive losses. Over is 7-0-1 in their last 8 games and are playing the Orioles and the Angels next.

The Athletics have a .255 batting average this season, a .321 OBP, and a .417 Slugging percentage. Athletics’ pitching staff has a 5.85 ERA and 1.55 WHIP. Jacob Wilson leads the Athletics with 81 hits and a team-high .355 batting average, while Tyler Soderstrom leads the team with 36 RBI, and Brent Booker adds a team-high 13 home runs.

Jeffrey Springs (L) will take the mound for the Athletics, and he has a 5-4 record, 4.72 ERA, and 1.38 WHIP. He has been weaker at home, with a 5.88 ERA across five home starts, and he has been torched in his last start, as he gave up 6 runs across just two innings of work against the Blue Jays. In his previous start against the Twins last season, he gave up one run in 6 innings of work.

Minnesota Twins Preview

The Minnesota Twins have a 33-27 record this season and are sitting in third place in the AL Central. The Twins have a 15-19 road record and are 22-33 in over/under. They are coming off a 10-3 road victory over the Athletics, and are playing the Rangers and the Blue Jays next.

The Twins have a .242 batting average this season, a .312 OBP, and a .385 Slugging percentage. Minnesota’s pitching staff has a 3.32 ERA and 1.16 WHIP. Trevor Larnach leads the Twins with 59 hits, while Byron Buxton adds a team-high 37 RBI, 10 home runs, and he is the team’s best hitter with a .274 batting average.

Zebby Matthews (R) will take the mound for the Twins, and he has a 0-1 record, 6.43 ERA, and 1.50 WHIP. He has been torched in his two road starts this season, having given up 8 runs in 10 innings of work, for a 7.20 ERA. This will be his first career start against the Athletics.

Why the Athletics will win

• The Twins have lost four of their last six games as road favorites against American League opponents following a road win.
• The Athletics have won four of their last five night games against AL Central opponents following a home loss.
• The Twins have failed to cover the run line in six of their last seven games following a win.
• The Athletics have covered the run line in eight of their last 10 night games against AL Central opponents following a loss.

Why the Minnesota Twins will win

• The Athletics have lost each of their last 14 night games after playing the previous day.
• The Twins have won each of their last 10 games against American League opponents that held a losing record.
• The Twins have covered the run line each of their last 10 games against American League opponents that held a losing record.
• The Athletics have failed to cover the run line in each of their last 10 night games against American League opponents.
• The Twins have led after 3 innings in seven of their last eight night games against opponents that held a losing record.
• The Athletics have trailed after 5 innings in eight of their last nine night games against American League opponents.

Total Runs Facts

• Each of the Athletics’ last seven night games against American League opponents have gone OVER the total runs line.
• Each of the Twins’ last six night games against AL West opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Athletics’ last seven night games against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Twins’ last 10 games as favorites against AL West opponents.

Matchup/League Facts

• The Athletics rank 30th in the league for ERA this season (5.85).
• The Athletics rank 30th in the league for home runs allowed this season (94).
• The Twins rank 1st in the league for walks allowed this season (148).
• The Twins rank T4th in the league for runs allowed this season (210).

Twins vs Athletics Prediction

The Twins are 10-2 in their last 12 overall meetings against the Athletics, and have won their last four visits in Oakland. Over is 5-1 in their last 6 meetings.

In this Twins vs Athletics Prediction, the Twins are coming as -140 road favorites. The Twins are rightfully favored, as they have a better overall record this season, and the A’s have been the second-worst home team in the league behind the Rockies. The Athletics are on a huge slump lately, having lost 18 of their last 19 games, but I don’t trust either pitcher in this matchup, as both have a combined 11.05 ERA. Both games of this series had 14 and 13 total runs, and I expect more of the same today with those two pitchers on the mound. Take the over 9.5 runs.