Twins vs Brewers Prediction 6/21/25 MLB Picks Today

The Milwaukee Brewers and the Minnesota Twins meet Saturday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Twins vs Brewers Prediction.

Starting Pitching Matchup

The Milwaukee Brewers will send out Jose Quintana for the start here and Quintana is 4-2 with a 3.35 ERA and 35 strikeouts this season. In his last five starts against the Twins, Quintana is 2-3 with a 4.55 ERA and 34 strikeouts. Simeon Woods-Richardson will get the start here for Minnesota and is 2-3 with a 5.13 ERA and 43 strikeouts this season. This will be Woods-Richardson’s first career start against the Brewers.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to build on their 17-6 win over the Minnesota Twins from Friday’s matchup to sit at 41-35 on the year. After this series, the Brewers will head home for a series against the Pittsburgh Pirates.

Brewers Win Back-To-Back Games

Brice Turang has 73 hits with 4 home runs, 26 RBIs and 16 stolen bases while Jackson Chourio has 85 hits with a team-high 22 doubles, 15 stolen bases, 12 home runs and 45 RBIs and Sal Frelick has 77 hits as well as 3 triples and 14 stolen bases so far this season. Christian Yelich also has 11 stolen bases with 14 homers and 52 RBIs while also adding 9 doubles. Yelich also has a team-high 82 strikeouts up to this point in the year. William Contreras has 6 homers and 33 RBIs as well this season. Rhys Hoskins has added 58 hits with 11 home runs, 38 RBIs and 9 doubles.

Why the Milwaukee Brewers will win

• The Twins have lost each of their last four games as favorites.
• The Brewers have won each of their last three games as road underdogs against the Twins.
• The road team has covered the run line in eight of the last nine games between the Brewers and Twins.
• The Twins have failed to cover the run line in seven of their last eight day games against National League opponents.

Milwaukee Brewers Player Prop Facts

• Rhys Hoskins has hit a home run in four of his seven previous appearances against the Twins after playing the previous day.
• Jackson Chourio has recorded at least one RBI in four of the Brewers’ last five games against AL opponents.
• Jose Quintana has recorded five or more strikeouts in each of his last 19 appearances against the Twins.
• Jackson Chourio has scored at least one run in each of his last six Saturday day appearances with the Brewers as underdogs.
• Rhys Hoskins has recorded at least one hit in each of his last 11 Saturday day appearances with his team as an underdog.
• Jose Quintana has recorded a win in four of his last five appearances against opponents that held a losing record.
• Christian Yelich has recorded at least one Double in four of his last five appearances at Target Field.
• Jackson Chourio ranks T10th in the league in Hits (85) this season.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to rebound from their loss at the hands of the Brewers on Friday to sit at 37-38 on the year. After this series, the Twins will square off against the Seattle Mariners at home.

Twins Drop 8 Of Their Last 10

Byron Buxton has 61 hits along with 9 doubles, a team-high 15 home runs and 45 RBIs with 12 stolen bases and 3 triples while Carlos Correa has 57 hits with 13 doubles and Willi Castro has 54 hits with 11 doubles as well. Harrison Bader’s added 7 home runs and 27 RBIs while Buxton’s contributed a team-high 68 strikeouts as well this season. Ty France has also added 71 hits, 13 doubles, 5 home runs and 40 RBIs and Trevor Larnach’s chipped in 66 hits with 11 doubles, 10 home runs and 35 RBIs as well this season.

Why the Minnesota Twins will win

• The Twins have won six of their last seven home games following a home loss.
• The Brewers have lost each of their last three day games following a win.
• The Brewers have failed to cover the run line in seven of their last eight games following a win.
• The Twins have covered the run line in six of their last seven home games following a home loss.

Minnesota Twins Player Prop Facts

• Byron Buxton has hit at least one home run in three of the Twins’ last four games against NL Central opponents.
• Ty France has recorded at least one RBI in seven of his last eight home appearances against opponents that held a winning record.
• Willi Castro has scored at least one run in eight of his last nine appearances in day games against NL teams that held a winning record.
• Willi Castro has recorded at least one hit in each of his last nine appearances in day games against NL teams that held a winning record.
• Trevor Larnach has recorded a Double in four of his last five appearances against NL opponents that held a winning record.
• Byron Buxton ranks 9th amongst qualified players for Slugging Percentage (.550) this season.

Total Runs Facts

• Each of the Twins’ last four home games against NL Central opponents have gone OVER the total runs line.
• Eleven of the Brewers’ last 14 road games against AL Central opponents have gone OVER the total runs line.

Twins vs Brewers Prediction

I’m on the Brewers here. I just see little value in backing the Twins in their current form, and the Twins continue to find new ways to lose baseball games. I also don’t think that Simeon Woods-Richardson is a viable option at the major league level for this rotation. The Twins just have serious issues right now and run hot and cold, and I think they take another L here. Give me the Brew Crew.