Twins vs Giants Prediction 5/11/25 MLB Picks Today

The San Francisco Giants and the Minnesota Twins meet Sunday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Twins vs Giants Prediction.

Starting Pitching Matchup

The San Francisco Giants will send out Landen Roupp for the start here, and Roupp is 2-3 with a 4.89 ERA and 39 strikeouts this season. This will be Roupp’s first career start against the Twins. Pablo Lopez will get the start for Minnesota here, and Lopez is 3-2 with a 2.18 ERA and 37 strikeouts this season. In his last five starts against the Giants, Lopez is 0-1 with a 2.10 ERA and 33 strikeouts.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to bounce back from their 2-1 loss to the Twins from Saturday’s matchup to slip to 24-16 on the year. After this series, the Giants will head home for a division series against the Arizona Diamondbacks.

Giants Looking To Avoid Sweep

Jung Hoo Lee leads the Giants with 43 hits, including a team-high 11 doubles along with a pair of triples, 4 home runs, and 23 RBIs with 3 stolen bases, while Heliot Ramos has 40 hits with 10 doubles, 6 home runs, and 15 RBIs. Wilmer Flores also has a team-high 7 home runs and 33 RBIs, while Mike Yastrzemski has 5 home runs with 17 RBIs and 7 doubles, and Matt Chapman and Tyler Fitzgerald each have a team-high 5 stolen bases as well on the year.

Why the San Francisco Giants will win

• The underdogs have won each of the Giants’ last four games.
• The Twins have lost six of their last seven games as home favorites against National League opponents following a win.
• The Giants have covered the run line in each of their last seven games as underdogs against AL Central opponents.
• The Twins have failed to cover the run line in each of their last seven games as home favorites against National League opponents following a home win.

San Francisco Giants Player Prop Facts

• Matt Chapman has scored at least one run in seven of the Giants’ last eight games.
• Heliot Ramos has recorded at least one Single in each of the Giants’ last four games against AL opponents.
• Willy Adames has recorded at least one hit in seven of his last eight appearances with his team as an underdog against AL Central opponents.
• Tom Murphy has recorded a Double in four of his last five road appearances against AL Central opponents.
• Tom Murphy has hit a home run in three of his last four appearances against the Twins.
• Tom Murphy has recorded an RBI in four of his last five appearances against the Twins.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to finish the job after picking up another win in Saturday’s matchup to improve their record to 20-20 on the year. After this series, the Twins will head on the road for a rematch series against the Baltimore Orioles.

Twins Win Seven In A Row, Get Back To .500

Byron Buxton has 37 hits along with 5 doubles, a team-high 9 home runs, and 25 RBIs with 8 stolen bases and a pair of triples, while Carlos Correa has 30 hits with 8 doubles, and Willi Castro has 17 hits with 6 doubles as well. Harrison Bader added 4 home runs and 16 RBIs while Buxton contributed a team-high 47 strikeouts as well this season. Ty France has also added 38 hits, 8 doubles, 3 home runs, and 21 RBIs, and Trevor Larnach chipped in 5 home runs and 17 RBIs as well this season.

Why the Minnesota Twins will win

• The Twins have won each of their last eight games at Target Field.
• The Giants have lost four of their last five road games against American League opponents.
• The Twins have covered the run line in each of their last 10 games following a win.
• The Giants have failed to cover the run line in seven of their last eight games against American League opponents.

Minnesota Twins Player Prop Facts

• Ryan Jeffers has hit at least one home run in five of his last nine appearances with the Twins as favorites against NL West opponents.
• Willi Castro has recorded a Double in each of the Twins’ last four day games against NL opponents that held a winning record.
• Trevor Larnach has recorded at least one RBI in each of the Twins’ last four games against opponents that held a winning record.
• Harrison Bader has scored at least one run in each of the Twins’ last five day games.
• Pablo Lopez has recorded seven or more strikeouts in each of his last four appearances in day games against teams that held a winning record.
• Carlos Correa has recorded at least one Single in each of his 10 previous home appearances against the Giants after playing the previous day.
• Harrison Bader has recorded at least one hit in each of his last 10 appearances against opponents that held a winning record.
• Pablo Lopez has recorded a win in six of his last seven home appearances.

Total Runs Facts

• Each of the Twins’ last eight day games as favorites have gone UNDER the total runs line.
• Twelve of the Giants’ last 13 games as underdogs have gone OVER the total runs line.

Twins vs Giants Prediction

I’m on the Twins in this one. I get the allure of backing the Giants because San Francisco is a solid team, and it’s hard to envision offensive struggles continuing and the possibility that this team could get swept here. However, the Twins’ pitching has been strong in this series, and Lopez is arguably Minnesota’s staff ace. I think that the Giants have issues here again, and as long as we’re getting reasonable prices with the Twins, I’ve got to keep backing them. Give me the Twins here.