Twins vs Mariners Prediction 4/28/26 MLB Picks Today
Seattle Mariners (14-16) vs. Minnesota Twins (13-16)
April 28, 2026 7:40 pm EDT
The Line: Minnesota Twins 109 / Seattle Mariners -131; Over/Under: 7.5
(Get latest betting odds)
In this article we will formulate a Twins vs Mariners prediction for this MLB game on Tuesday, April 28th at Target Field in Minneapolis, Minnesota. Let’s take a look at the prediction for this MLB matchup.
Minnesota Twins Betting Preview
The Minnesota Twins are 13-16 this year after they won game one by a score of 11-4 on Monday night. Minnesota jumped out to a 7-0 lead and they were able to coast to the easy victory. The Twins recorded 12 hits in the game and they were led by Clemens, who went 2-5 with one home run and five RBIs. Prielipp allowed one hit and two earned runs over 5.0 innings for the win, while Morris allowed two earned runs in relief. Prior to this series, Minnesota lost all three against the Rays and two out of three against the Mets.
This season, Minnesota has a 4.30 ERA with a 1.36 WHIP and a .251 opponent batting average, while they have scored 143 runs with a .231 batting average and a .329 on base percentage. Ryan Jeffers has led the Twins with three home runs and 18 RBIs, while Josh Bell has added three home runs and 16 RBIs. The projected starting pitcher for Minnesota is Joe Ryan, who is 2-2 with a 3.90 ERA and a 1.02 WHIP over 32.1 innings pitched this year.
Seattle Mariners Betting Preview
The Seattle Mariners are 14-16 this season after they lost game one by a score of 11-4 last night. Seattle cut the deficit to 8-4 in the eighth inning, but they allowed three more runs in the ugly loss. The Mariners recorded five hits in the game and they were led by Raleigh, who went 1-4 with one home run and two RBIs. Castillo allowed seven hits and seven earned runs over 5.0 innings for the loss, while Hoppe allowed three earned runs in relief. Prior to this series, Seattle swept the Cardinals in three games, but lost two out of three against the Athletics before that.
This season, Seattle has a 3.78 ERA with a 1.26 WHIP and a .261 opponent batting average, while they have scored 122 runs with a .232 batting average and a .322 on base percentage. Cal Raleigh has led the Mariners with seven home runs and 17 RBIs, while Cole Young has added three home runs and 15 RBIs. The projected starting pitcher for Seattle is Logan Gilbert, who is 1-3 with a 4.36 ERA and a 1.27 WHIP over 33.0 innings pitched this season.
Why the Minnesota Twins will win
- The underdogs have won nine of the Twins’ last 10 games at Target Field.
- The Mariners have lost each of their last five games as road favorites against American League opponents.
- The Mariners have failed to cover the run line in nine of their last 10 games as road favorites.
- The underdogs have covered the run line in nine of the Twins’ last 10 games at Target Field.
- The Twins have led after 3 innings in each of their last five night games against American League opponents that held a losing record.
- The Twins have led after 5 innings in each of their last six night games at Target Field against American League opponents.
- The Twins have won the first inning in four of their last five night games against American League opponents that held a losing record.
Why the Seattle Mariners will win
- The Twins have lost eight of their last nine games after playing the previous day.
- The Mariners have won eight of their last nine night games against the Twins following a road loss.
- The Twins have failed to cover the run line in each of their last seven games as home underdogs against AL West opponents following a win.
- The Mariners have covered the run line in eight of their last nine night games at Target Field following a loss.
- The Mariners have won the first inning in four of their last five games against opponents that held a losing record.
- The Twins have trailed after 3 innings in four of their last five games against opponents that held a losing record.
- The Twins have trailed after 5 innings in seven of their last eight games as underdogs.
Total Runs Facts
- Seven of the last eight games between the Mariners and Twins at Target Field have gone OVER the total runs line.
- Six of the Mariners’ last seven games as favorites against AL Central opponents have gone OVER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Twins’ last eight home games against AL West opponents.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of Logan Gilbert’s last six appearances as a starter.
Minnesota Twins Player Prop Facts
- Byron Buxton has hit at least one home run in five of the Twins’ last six night games against opponents that held a losing record.
- Trevor Larnach has recorded at least one hit in each of his last 12 appearances with the Twins as underdogs against AL West opponents.
- Joe Ryan has recorded six or more strikeouts in seven of his last eight appearances against AL West opponents.
- Joe Ryan has recorded a win in five of his last six appearances against AL opponents that held a losing record.
Seattle Mariners Player Prop Facts
- Cal Raleigh has hit a home run in each of the Mariners’ last four games against AL opponents.
- Logan Gilbert has recorded six or more strikeouts in 17 of his last 18 appearances against AL opponents that held a losing record.
- Logan Gilbert has recorded a win in each of his last three appearances with the Mariners as road favorites.
- Brendan Donovan has recorded at least one hit in each of his last 12 Tuesday appearances against teams that held a losing record.
Twins vs Mariners Prediction
Minnesota jumped all over the Mariners on Monday night to snap their losing streak, but they have allowed 30 runs in their last five games. The Twins are 8-6 at home this year, while the Mariners are 4-9 on the road. Seattle had their winning streak snapped in game one and they have allowed 22 runs in their last three games. The Mariners are starting Gilbert, who has allowed two earned runs or fewer in three of his last four starts, while Ryan has also allowed two earned runs or fewer in three of his last four. The pitching matchup seems pretty even, but I am going to fade Seattle and their bad road record. Take the Twins here.