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Twins vs White Sox Prediction 4/23/25 MLB Picks Today

Chicago White Sox (5-18) vs. Minnesota Twins (8-15)
April 23, 2025 7:40 pm EDT
The Line: Minnesota Twins -285 / Chicago White Sox 230; Over/Under: 8.5
(Get latest betting odds)

In this article, we will formulate a Twins vs White Sox Prediction for this MLB game on Wednesday, April 23rd, at Target Field. Let’s take a look at a Minnesota Twins vs Chicago White Sox pick. 

White Sox Are Awful 

The White Sox are awful, and they continued the trend on Tuesday. The White Sox failed to pick up clutch hits with runners in scoring position, and that led to the defeat. The White Sox had ten hits, but only two runs, and if they want to win, that can’t happen again. Davis Martin got the start, and he was good, going five innings, giving up three hits and zero runs. 

The White Sox are averaging 3.18 runs while their pitching is giving up 4.45 runs per game. The offense is ranked 28th in the league while the defense is ranked 18th. Andrew Benintendi has hit four home runs and driven in eight RBIs. 

Byron Buxton to the Rescue

The Twins’ bullpen tried to blow another game on Tuesday, but it was Byron Buxton who laid out in center field to prevent the White Sox from tying the game and clinching the win for Minnesota. Bailey Ober went six innings, giving up eight hits and one run. Even though they won, the offense still wasn’t all that great in terms of scoring. 

The Twins are averaging 3.41 runs while their pitching is giving up 4.32 runs per game. The offense is ranked 25th while the defense is ranked 15th. This is too talented of an offense to continue to be so bad. Getting the start for the Twins will be David Festa, who sits with a 0-0 record and an ERA of 0.00. In his last game against the New York Mets, he went 4.1 innings, giving up five hits and zero runs. 

Why the Twins Will Beat the White Sox

  • The White Sox have lost each of their last 13 games at Target Field.
  • The Twins have won each of their last nine home games against the White Sox following a win.
  • The White Sox have failed to cover the run line in 12 of their last 13 games at Target Field against American League opponents that held a losing record.
  • The favorites have covered the run line in each of the last six games between the White Sox and Twins at Target Field.
  • The White Sox have trailed after 3 innings in each of their last four games at Target Field.
  • The Twins have led after 5 innings in each of their last five home games against AL Central opponents that held a losing record.

Twins vs White Sox Prediction

The Twins are going to have no issue putting on a show here. Have they struggled all season? Yes, they have, but David Festa has also been dominant this season. In nine innings his year, he has given up zero earned runs, and he’s going to step up again here. The Twins might only score three or four runs, but that is still going to be enough for them to cruise to the victory. Back the Twins on the run line. In terms of the total, I do believe this is going to also end up being a lower-scoring game. I really like both of these plays a lot. 

Shane Mickle's Free Pick: Twins -1.5

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Shane Mickle

Sports is about all Shane knows in this life! He has a passion for sports and writing, which makes working for Sportschatplace a perfect job for him! If you find him cheering for a team it's usually a Minnesota team, or the Kansas Jayhawks!

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